| 24 Nov 20 | r04  | GenclerbirligiGenclerbirlig | 1 - 0 | Kırşehir BelediyesporKırşehir Bele |
| 24 Nov 20 | r04 | BolusporBoluspor | 2 - 1 | KahramanmaraşsporKahramanmaraş |
| 24 Nov 20 | r04 | GiresunsporGiresunspor | 1 - 1 | Niğde AnadoluNiğde Anadolu |
| 24 Nov 20 | r04 | DenizlisporDenizlispor | 1 - 2 | TurgutlusporTurgutluspor |
| 24 Nov 20 | r04 | AdanasporAdanaspor | 2 - 2 | SakaryasporSakaryaspor |
| 24 Nov 20 | r04 | BursasporBursaspor | 1 - 0 | Anadolu SelçuksporAnadolu Selçu |
| 24 Nov 20 | r04 | FenerbahceFenerbahce | 4 - 0 | Sivas BelediyesporSivas Belediy |
| 25 Nov 20 | r04 | KeçiörengücüKeçiörengücü | 1 - 2 | KocaelisporKocaelispor |
| 25 Nov 20 | r04 | MalatyasporMalatyaspor | 2 - 0 | Etimesgut BelediyesporEtimesgut Bel |
| 25 Nov 20 | r04 | IstanbulsporIstanbulspor | 0 - 1 | Tarsus İdman YurduTarsus İdman |
| 25 Nov 20 | r04 | AltınorduAltınordu | - | Yeni ÇorumsporYeni Çorumspo |
| 25 Nov 20 | r04 | EskisehirsporEskisehirspor | 2 - 0 | Kastamonuspor 1966Kastamonuspor |
| 25 Nov 20 | r04 | HataysporHatayspor | 2 - 2 | Karacabey BelediyesporKaracabey Bel |
| 25 Nov 20 | r04 | Gaziantep FKGaziantep FK | 3 - 0 | Serik BelediyesporSerik Belediy |
| 25 Nov 20 | r04 | Adana DemirsporAdana Demirsp | 4 - 1 | Afjet AfyonsporAfjet Afyonsp |
| 25 Nov 20 | r04 | AntalyasporAntalyaspor | 2 - 0 | PendiksporPendikspor |
| 25 Nov 20 | r04 | RizesporRizespor | 6 - 0 | Utaş UşaksporUtaş Uşakspor |
| 26 Nov 20 | r04 | ErzurumsporErzurumspor | 3 - 2 | Ankara DemirsporAnkara Demirs |
| 26 Nov 20 | r04 | KasimpasaKasimpasa | 3 - 0 | 24 Erzincanspor24 Erzincansp |
| 26 Nov 20 | r04 | KayserisporKayserispor | 3 - 3 | Hekimoğlu TrabzonHekimoğlu Tra |
| 26 Nov 20 | r04 | KonyasporKonyaspor | 7 - 0 | Manisa BBSKManisa BBSK |
| 26 Nov 20 | r04 | GoztepeGoztepe | 2 - 0 | KırklarelisporKırklarelispo |
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