| 17 Apr 21 | r01  | Atlético Vega RealAtlético Vega | 2 - 1 | AtlánticoAtlántico |
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| 25 Apr 21 | r02 | JarabacoaJarabacoa | 2 - 1 | Atlético Vega RealAtlético Vega |
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| 02 May 21 | r03 | Atlético Vega RealAtlético Vega | 3 - 0 | Atlético San CristóbalAtlético San |
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| 08 May 21 | r04 | MocaMoca | 1 - 1 | Atlético Vega RealAtlético Vega |
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| 15 May 21 | r05 | Atlético San FranciscoAtlético San | 0 - 2 | Atlético Vega RealAtlético Vega |
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| 21 May 21 | r06 | Atlético PantojaAtlético Pant | 1 - 1 | Atlético Vega RealAtlético Vega |
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| 29 May 21 | r07 | Delfines del EsteDelfines del | 1 - 3 | Atlético Vega RealAtlético Vega |
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| 05 Jun 21 | r08 | Atlético Vega RealAtlético Vega | 0 - 0 | Universidad O&MUniversidad O |
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| 09 Jun 21 | r09 | Atlético Vega RealAtlético Vega | 1 - 2 | CibaoCibao |
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| 13 Jun 21 | r10 | Atlético Vega RealAtlético Vega | 1 - 3 | JarabacoaJarabacoa |
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| 20 Jun 21 | r11 | CibaoCibao | 1 - 0 | Atlético Vega RealAtlético Vega |
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| 23 Jun 21 | r12 | Atlético San CristóbalAtlético San | 0 - 1 | Atlético Vega RealAtlético Vega |
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| 26 Jun 21 | r13 | Atlético Vega RealAtlético Vega | 0 - 2 | MocaMoca |
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| 03 Jul 21 | r14 | Atlético Vega RealAtlético Vega | 3 - 2 | Delfines del EsteDelfines del |
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| 07 Jul 21 | r15 | Atlético Vega RealAtlético Vega | 1 - 2 | Atlético PantojaAtlético Pant |
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| 10 Jul 21 | r16 | Universidad O&MUniversidad O | 1 - 3 | Atlético Vega RealAtlético Vega |
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| 18 Jul 21 | r17 | Atlético Vega RealAtlético Vega | 2 - 3 | Atlético San FranciscoAtlético San |
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| 22 Jul 21 | r18 | AtlánticoAtlántico | 4 - 1 | Atlético Vega RealAtlético Vega |
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| 01 Aug 21 | r01 | MocaMoca | 0 - 0 | Atlético Vega RealAtlético Vega |
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| 08 Aug 21 | r02 | Atlético Vega RealAtlético Vega | 2 - 1 | Universidad O&MUniversidad O |
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| 15 Aug 21 | r03 | Atlético Vega RealAtlético Vega | 0 - 1 | Atlético PantojaAtlético Pant |
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| 22 Aug 21 | r04 | CibaoCibao | 4 - 0 | Atlético Vega RealAtlético Vega |
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| 29 Aug 21 | r05 | Atlético Vega RealAtlético Vega | 3 - 3 | JarabacoaJarabacoa |
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| 05 Sep 21 | r06 | Atlético Vega RealAtlético Vega | 1 - 0 | MocaMoca |
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| 11 Sep 21 | r07 | Universidad O&MUniversidad O | 2 - 3 | Atlético Vega RealAtlético Vega |
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| 18 Sep 21 | r08 | Atlético PantojaAtlético Pant | 0 - 1 | Atlético Vega RealAtlético Vega |
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| 26 Sep 21 | r09 | JarabacoaJarabacoa | 1 - 1 | Atlético Vega RealAtlético Vega |
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| 02 Oct 21 | r10 | Atlético Vega RealAtlético Vega | 1 - 0 | CibaoCibao |
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| 09 Oct 21 | r00 | JarabacoaJarabacoa | 0 - 1 | Atlético Vega RealAtlético Vega |
| 17 Oct 21 | r00 | Atlético Vega RealAtlético Vega | 2 - 1 | JarabacoaJarabacoa |
| 24 Oct 21 | r00 | CibaoCibao | 1 - 1 | Atlético Vega RealAtlético Vega |
| 31 Oct 21 | r00 | Atlético Vega RealAtlético Vega | 1 - 3 | CibaoCibao |
Team 2021 Schedules
Atlántico
Atlético Pantoja
Atlético San Cristóbal
Atlético Vega Real
Barcelona Atlético
Cibao
Delfines del Este
Jarabacoa
Moca
Salcedo
Santa Fe
Universidad O and M
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