| 13 Aug 21 | r01  | SesveteSesvete | 1 - 4 | Osijek IIOsijek II |
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| 21 Aug 21 | r02 | SesveteSesvete | 1 - 0 | DugopoljeDugopolje |
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| 28 Aug 21 | r03 | DubravaDubrava | 0 - 0 | SesveteSesvete |
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| 10 Sep 21 | r04 | SesveteSesvete | 0 - 1 | Orijent 1919Orijent 1919 |
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| 15 Sep 21 | r05 | CibaliaCibalia | 0 - 1 | SesveteSesvete |
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| 18 Sep 21 | r06 | SesveteSesvete | 1 - 2 | NK Inter ZaprešićNK Inter Zapr |
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| 25 Sep 21 | r07 | KustošijaKustošija | 1 - 2 | SesveteSesvete |
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| 01 Oct 21 | r08 | SesveteSesvete | 0 - 1 | BSK Bijelo BrdoBSK Bijelo Br |
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| 17 Oct 21 | r09 | Dinamo Zagreb IIDinamo Zagreb | 2 - 1 | SesveteSesvete |
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| 22 Oct 21 | r10 | SesveteSesvete | 4 - 0 | SolinSolin |
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| 31 Oct 21 | r11 | Croatia ZmijavciCroatia Zmija | 1 - 0 | SesveteSesvete |
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| 05 Nov 21 | r12 | SesveteSesvete | 2 - 1 | OpatijaOpatija |
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| 20 Nov 21 | r13 | NK VaraždinNK Varaždin | 2 - 1 | SesveteSesvete |
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| 26 Nov 21 | r14 | SesveteSesvete | 0 - 0 | RudešRudeš |
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| 04 Dec 21 | r15 | JarunJarun | 4 - 3 | SesveteSesvete |
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| 12 Feb 22 | r16 | Osijek IIOsijek II | 0 - 3 | SesveteSesvete |
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| 19 Feb 22 | r17 | DugopoljeDugopolje | 2 - 1 | SesveteSesvete |
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| 26 Feb 22 | r18 | SesveteSesvete | 0 - 0 | DubravaDubrava |
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| 05 Mar 22 | r19 | Orijent 1919Orijent 1919 | 0 - 3 | SesveteSesvete |
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| 11 Mar 22 | r20 | SesveteSesvete | 1 - 1 | CibaliaCibalia |
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| 18 Mar 22 | r21 | NK Inter ZaprešićNK Inter Zapr | 2 - 0 | SesveteSesvete |
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| 01 Apr 22 | r22 | SesveteSesvete | 0 - 2 | KustošijaKustošija |
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| 10 Apr 22 | r23 | BSK Bijelo BrdoBSK Bijelo Br | 0 - 0 | SesveteSesvete |
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| 15 Apr 22 | r24 | SesveteSesvete | 4 - 0 | Dinamo Zagreb IIDinamo Zagreb |
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| 23 Apr 22 | r25 | SolinSolin | 4 - 0 | SesveteSesvete |
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| 01 May 22 | r26 | SesveteSesvete | 2 - 2 | Croatia ZmijavciCroatia Zmija |
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| 06 May 22 | r27 | OpatijaOpatija | 1 - 1 | SesveteSesvete |
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| 13 May 22 | r28 | SesveteSesvete | 2 - 3 | NK VaraždinNK Varaždin |
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| 21 May 22 | r29 | RudešRudeš | 3 - 0 | SesveteSesvete |
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| 27 May 22 | r30 | SesveteSesvete | 3 - 2 | JarunJarun |
Team 2021-2022 Schedules
BSK Bijelo Brdo
Cibalia
Croatia Zmijavci
Dubrava
Dugopolje
Hrvace
Jarun
Karlovac
Opatija
Orijent
Rudeš
Sesvete
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