| 23 Feb 25 | r01     | Deportes Santa CruzDeportes Sant | 0 - 3 | Rangers de TalcaRangers de Ta |
| |
| 28 Feb 25 | r02 | Deportes RecoletaDeportes Reco | 3 - 2 | Deportes Santa CruzDeportes Sant |
| |
| 09 Mar 25 | r03 | San Luis de QuillotaSan Luis de Q | 1 - 1 | Deportes Santa CruzDeportes Sant |
| |
| 16 Mar 25 | r04 | Deportes Santa CruzDeportes Sant | 2 - 0 | Deportes ConcepciónDeportes Conc |
| |
| 28 Mar 25 | r05 | Universidad de ConcepciónUniversidad d | 1 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 13 Apr 25 | r06 | Deportes Santa CruzDeportes Sant | 0 - 2 | Santiago MorningSantiago Morn |
| |
| 18 Apr 25 | r07 | Curicó UnidoCuricó Unido | 2 - 3 | Deportes Santa CruzDeportes Sant |
| |
| 26 Apr 25 | r08 | Deportes Santa CruzDeportes Sant | 0 - 1 | Deportes CopiapóDeportes Copi |
| |
| 05 May 25 | r09 | MagallanesMagallanes | 3 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 18 May 25 | r10 | Deportes Santa CruzDeportes Sant | 2 - 2 | Santiago WanderersSantiago Wand |
| |
| 23 May 25 | r11 | CobreloaCobreloa | 1 - 1 | Deportes Santa CruzDeportes Sant |
| |
| 01 Jun 25 | r12 | Deportes Santa CruzDeportes Sant | 1 - 1 | Unión San FelipeUnión San Fel |
| |
| 15 Jun 25 | r14 | San Marcos de AricaSan Marcos de | 2 - 1 | Deportes Santa CruzDeportes Sant |
| |
| 22 Jun 25 | r15 | Deportes Santa CruzDeportes Sant | 3 - 0 | Deportes AntofagastaDeportes Anto |
| |
| 05 Jul 25 | r13 | Deportes Santa CruzDeportes Sant | 2 - 0 | Deportes TemucoDeportes Temu |
| |
| 12 Jul 25 | r16 | Rangers de TalcaRangers de Ta | 2 - 2 | Deportes Santa CruzDeportes Sant |
| |
| 19 Jul 25 | r17 | Deportes Santa CruzDeportes Sant | 0 - 0 | Deportes RecoletaDeportes Reco |
| |
| 26 Jul 25 | r18 | Deportes Santa CruzDeportes Sant | 2 - 2 | San Luis de QuillotaSan Luis de Q |
| |
| 04 Aug 25 | r19 | Deportes ConcepciónDeportes Conc | 1 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 09 Aug 25 | r20 | Deportes Santa CruzDeportes Sant | 1 - 2 | Universidad de ConcepciónUniversidad d |
| |
| 15 Aug 25 | r21 | Santiago MorningSantiago Morn | 0 - 1 | Deportes Santa CruzDeportes Sant |
| |
| 24 Aug 25 | r22 | Deportes Santa CruzDeportes Sant | 2 - 0 | Curicó UnidoCuricó Unido |
| |
| 30 Aug 25 | r23 | Deportes CopiapóDeportes Copi | 2 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 07 Sep 25 | r24 | Deportes Santa CruzDeportes Sant | 0 - 3 | MagallanesMagallanes |
| |
| 14 Sep 25 | r25 | Santiago WanderersSantiago Wand | 1 - 1 | Deportes Santa CruzDeportes Sant |
| |
| 04 Oct 25 | r26  | Deportes Santa CruzDeportes Sant | 1 - 2 | CobreloaCobreloa |
| |
| 12 Oct 25 | r27 | Unión San FelipeUnión San Fel | 0 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 19 Oct 25 | r28 | Deportes TemucoDeportes Temu | 0 - 0 | Deportes Santa CruzDeportes Sant |
| |
| 25 Oct 25 | r29 | Deportes Santa CruzDeportes Sant | 1 - 0 | San Marcos de AricaSan Marcos de |
| |
| 02 Nov 25 | r30 | Deportes AntofagastaDeportes Anto | 2 - 1 | Deportes Santa CruzDeportes Sant |
Team 2025 Schedules
Cobreloa
Curicó Unido
Deportes Antofagasta
Deportes Copiapó
Deportes Iquique
Deportes Puerto Montt
Deportes Recoleta
Deportes Santa Cruz
Deportes Temuco
Magallanes
Rangers de Talca
San Luis de Quillota
San Marcos de Arica
Santiago Wanderers
Unión Española
Unión San Felipe
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