| 31 Oct 20 | r53  | ExtremaduraExtremadura | 0 - 1 | BadajozBadajoz |
| 31 Oct 20 | r53 | VillarrubiaVillarrubia | 2 - 1 | Mérida ADMérida AD |
| 01 Nov 20 | r53 | Getafe BGetafe B | 0 - 1 | NavalcarneroNavalcarnero |
| 01 Nov 20 | r53 | SS ReyesSS Reyes | 2 - 1 | Inter de MadridInter de Madr |
| 01 Nov 20 | r53 | Atlético BalearesAtlético Bale | 1 - 1 | Atlético Madrid BAtlético Madr |
| 01 Nov 20 | r53 | Don BenitoDon Benito | 1 - 0 | VillarrobledoVillarrobledo |
| 01 Nov 20 | r53 | Las Rozas CFLas Rozas CF | 1 - 1 | PoblensePoblense |
| 01 Nov 20 | r53 | SocuéllamosSocuéllamos | 1 - 2 | TalaveraTalavera |
| 01 Nov 20 | r53 | MelillaMelilla | 1 - 0 | VillanovenseVillanovense |
| 15 Nov 20 | r53 | Rayo MajadahondaRayo Majadaho | 1 - 0 | Real Madrid BReal Madrid B |
| 17 Apr 21 | r53 | Rayo MajadahondaRayo Majadaho | 0 - 2 | VillanovenseVillanovense |
| 17 Apr 21 | r53 | Real Madrid BReal Madrid B | 2 - 2 | TalaveraTalavera |
| 18 Apr 21 | r53 | SS ReyesSS Reyes | 0 - 4 | BadajozBadajoz |
| 18 Apr 21 | r53 | Atlético BalearesAtlético Bale | 2 - 1 | Mérida ADMérida AD |
| 18 Apr 21 | r53 | Getafe BGetafe B | 0 - 0 | SocuéllamosSocuéllamos |
| 18 Apr 21 | r53 | Las Rozas CFLas Rozas CF | 1 - 1 | VillarrubiaVillarrubia |
| 18 Apr 21 | r53 | PoblensePoblense | 4 - 0 | VillarrobledoVillarrobledo |
| 18 Apr 21 | r53 | NavalcarneroNavalcarnero | 0 - 0 | Don BenitoDon Benito |
| 18 Apr 21 | r53 | Inter de MadridInter de Madr | 1 - 0 | ExtremaduraExtremadura |
| 05 May 21 | r53 | Atlético Madrid BAtlético Madr | 0 - 2 | MelillaMelilla |
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