| 17 Oct 20 | r51  | VillarrubiaVillarrubia | 0 - 3 | VillanovenseVillanovense |
| 18 Oct 20 | r51 | Atlético Madrid BAtlético Madr | 1 - 0 | PoblensePoblense |
| 18 Oct 20 | r51 | Getafe BGetafe B | 1 - 2 | Rayo MajadahondaRayo Majadaho |
| 18 Oct 20 | r51 | Las Rozas CFLas Rozas CF | 1 - 2 | Real Madrid BReal Madrid B |
| 18 Oct 20 | r51 | Atlético BalearesAtlético Bale | 4 - 0 | Inter de MadridInter de Madr |
| 18 Oct 20 | r51 | MelillaMelilla | 3 - 0 | VillarrobledoVillarrobledo |
| 18 Oct 20 | r51 | SS ReyesSS Reyes | 0 - 1 | NavalcarneroNavalcarnero |
| 18 Oct 20 | r51 | SocuéllamosSocuéllamos | 1 - 1 | BadajozBadajoz |
| 18 Oct 20 | r51 | Mérida ADMérida AD | 0 - 1 | TalaveraTalavera |
| 14 Nov 20 | r51 | Don BenitoDon Benito | 1 - 2 | ExtremaduraExtremadura |
| 03 Apr 21 | r51 | Rayo MajadahondaRayo Majadaho | 2 - 1 | Mérida ADMérida AD |
| 04 Apr 21 | r51 | Getafe BGetafe B | 2 - 2 | MelillaMelilla |
| 04 Apr 21 | r51 | SS ReyesSS Reyes | 2 - 1 | TalaveraTalavera |
| 04 Apr 21 | r51 | Inter de MadridInter de Madr | 0 - 2 | BadajozBadajoz |
| 04 Apr 21 | r51 | Atlético BalearesAtlético Bale | 1 - 0 | Don BenitoDon Benito |
| 04 Apr 21 | r51 | Atlético Madrid BAtlético Madr | 0 - 1 | SocuéllamosSocuéllamos |
| 04 Apr 21 | r51 | PoblensePoblense | 2 - 1 | VillarrubiaVillarrubia |
| 04 Apr 21 | r51 | NavalcarneroNavalcarnero | 0 - 2 | VillanovenseVillanovense |
| 04 Apr 21 | r51 | Las Rozas CFLas Rozas CF | 0 - 0 | VillarrobledoVillarrobledo |
| 04 Apr 21 | r51 | Real Madrid BReal Madrid B | 1 - 1 | ExtremaduraExtremadura |
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