| 26 Jan 20 | r01  | Atlético ChiriquíAtlético Chir | 0 - 2 | San Francisco FCSan Francisco |
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| 01 Feb 20 | r02 | San Francisco FCSan Francisco | 6 - 3 | Plaza AmadorPlaza Amador |
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| 08 Feb 20 | r03 | AlianzaAlianza | 2 - 1 | San Francisco FCSan Francisco |
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| 16 Feb 20 | r04 | San Francisco FCSan Francisco | 0 - 2 | CD UniversitarioCD Universita |
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| 20 Feb 20 | r05 | Independiente de La ChorrIndependiente | 1 - 1 | San Francisco FCSan Francisco |
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| 29 Feb 20 | r06 | San Francisco FCSan Francisco | 0 - 0 | Sporting San MiguelitoSporting San |
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| 04 Mar 20 | r07 | San Francisco FCSan Francisco | 1 - 0 | Tauro FCTauro FC |
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| 08 Mar 20 | r08 | Costa del EsteCosta del Est | 1 - 0 | San Francisco FCSan Francisco |
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| 14 Mar 20 | r09 | Árabe UnidoÁrabe Unido | - | San Francisco FCSan Francisco |
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| 21 Mar 20 | r10 | San Francisco FCSan Francisco | - | Atlético ChiriquíAtlético Chir |
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| 28 Mar 20 | r11 | Plaza AmadorPlaza Amador | - | San Francisco FCSan Francisco |
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| 04 Apr 20 | r12 | San Francisco FCSan Francisco | - | AlianzaAlianza |
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| 09 Apr 20 | r13 | CD UniversitarioCD Universita | - | San Francisco FCSan Francisco |
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| 18 Apr 20 | r14 | San Francisco FCSan Francisco | - | Independiente de La ChorrIndependiente |
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| 26 Apr 20 | r15 | Sporting San MiguelitoSporting San | - | San Francisco FCSan Francisco |
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| 29 Apr 20 | r16 | Tauro FCTauro FC | - | San Francisco FCSan Francisco |
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| 02 May 20 | r17 | San Francisco FCSan Francisco | - | Costa del EsteCosta del Est |
| |
| 09 May 20 | r18 | San Francisco FCSan Francisco | - | Árabe UnidoÁrabe Unido |
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| 24 Oct 20 | r01 | San Francisco FCSan Francisco | 1 - 1 | Atlético ChiriquíAtlético Chir |
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| 31 Oct 20 | r02 | Plaza AmadorPlaza Amador | 0 - 0 | San Francisco FCSan Francisco |
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| 09 Nov 20 | r03 | San Francisco FCSan Francisco | 0 - 0 | AlianzaAlianza |
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| 14 Nov 20 | r04 | CD UniversitarioCD Universita | 0 - 1 | San Francisco FCSan Francisco |
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| 18 Nov 20 | r05 | Sporting San MiguelitoSporting San | 1 - 2 | San Francisco FCSan Francisco |
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| 28 Nov 20 | r08 | San Francisco FCSan Francisco | 3 - 0 | Árabe UnidoÁrabe Unido |
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| 01 Dec 20 | r06 | San Francisco FCSan Francisco | 1 - 1 | Independiente de La ChorrIndependiente |
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| 04 Dec 20 | r07 | Tauro FCTauro FC | 1 - 0 | San Francisco FCSan Francisco |
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| 07 Dec 20 | r09 | San Francisco FCSan Francisco | 0 - 0 | Costa del EsteCosta del Est |
| |
| 11 Dec 20 | r00 | San Francisco FCSan Francisco | 1 - 0 | Plaza AmadorPlaza Amador |
| 14 Dec 20 | r00 | San Francisco FCSan Francisco | 2 - 0 | Tauro FCTauro FC |
| 17 Dec 20 | r00 | Tauro FCTauro FC | 2 - 2 | San Francisco FCSan Francisco |
| 20 Dec 20 | r00 | Independiente de La ChorrIndependiente | 3 - 1 | San Francisco FCSan Francisco |
Team 2020-2021 Schedules
Alianza
CD Universitario
Deportivo Árabe Unido
Herrera
Independiente de La Chorrera
Plaza Amador
San Francisco FC
Sporting San Miguelito
Tauro
UMECIT
Unión Coclé
Veraguas United
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