| 31 Jul 22 | r01  | MotaguaMotagua | 4 - 0 | Honduras ProgresoHonduras Prog |
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| 08 Aug 22 | r02  | Real EspañaReal España | 1 - 1 | MotaguaMotagua |
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| 11 Aug 22 | r03 | MotaguaMotagua | 2 - 2 | VidaVida |
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| 14 Aug 22 | r04 | MotaguaMotagua | 4 - 1 | CD MarathónCD Marathón |
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| 21 Aug 22 | r05 | Lobos UPNFMLobos UPNFM | 2 - 3 | MotaguaMotagua |
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| 28 Aug 22 | r06 | OlanchoOlancho | 0 - 1 | MotaguaMotagua |
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| 02 Sep 22 | r07 | MotaguaMotagua | 1 - 0 | CD OlimpiaCD Olimpia |
| |
| 04 Sep 22 | r08 | Real Sociedad TocoaReal Sociedad | 1 - 2 | MotaguaMotagua |
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| 11 Sep 22 | r09 | MotaguaMotagua | 2 - 1 | CD VictoriaCD Victoria |
| |
| 18 Sep 22 | r10 | Honduras ProgresoHonduras Prog | 0 - 1 | MotaguaMotagua |
| |
| 02 Oct 22 | r11 | MotaguaMotagua | 1 - 2 | Real EspañaReal España |
| |
| 09 Oct 22 | r12 | VidaVida | 0 - 3 | MotaguaMotagua |
| |
| 15 Oct 22 | r13 | CD MarathónCD Marathón | 2 - 2 | MotaguaMotagua |
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| 21 Oct 22 | r14 | MotaguaMotagua | 2 - 2 | Lobos UPNFMLobos UPNFM |
| |
| 23 Oct 22 | r15 | MotaguaMotagua | 1 - 3 | OlanchoOlancho |
| |
| 07 Nov 22 | r16 | CD OlimpiaCD Olimpia | 4 - 0 | MotaguaMotagua |
| |
| 12 Nov 22 | r17 | MotaguaMotagua | 2 - 2 | Real Sociedad TocoaReal Sociedad |
| |
| 19 Nov 22 | r18 | CD VictoriaCD Victoria | 1 - 0 | MotaguaMotagua |
| |
| 09 Dec 22 | r00 | MotaguaMotagua | 0 - 1 | CD OlimpiaCD Olimpia |
| 18 Dec 22 | r00 | CD OlimpiaCD Olimpia | 2 - 0 | MotaguaMotagua |
| |
| 21 Jan 23 | r01 | Lobos UPNFMLobos UPNFM | 2 - 1 | MotaguaMotagua |
| |
| 26 Jan 23 | r02 | MotaguaMotagua | 1 - 0 | Real EspañaReal España |
| |
| 29 Jan 23 | r03 | CD VictoriaCD Victoria | 2 - 2 | MotaguaMotagua |
| |
| 02 Feb 23 | r04 | MotaguaMotagua | 0 - 1 | OlanchoOlancho |
| |
| 05 Feb 23 | r05 | CD OlimpiaCD Olimpia | 3 - 1 | MotaguaMotagua |
| |
| 11 Feb 23 | r06 | MotaguaMotagua | 2 - 1 | VidaVida |
| |
| 16 Feb 23 | r07 | Real Sociedad TocoaReal Sociedad | 0 - 0 | MotaguaMotagua |
| |
| 19 Feb 23 | r08 | CD MarathónCD Marathón | 1 - 1 | MotaguaMotagua |
| |
| 26 Feb 23 | r09 | MotaguaMotagua | 1 - 1 | Honduras ProgresoHonduras Prog |
| |
| 02 Mar 23 | r10 | MotaguaMotagua | 4 - 3 | Lobos UPNFMLobos UPNFM |
| |
| 05 Mar 23 | r11 | Real EspañaReal España | 0 - 3 | MotaguaMotagua |
| |
| 12 Mar 23 | r12 | MotaguaMotagua | 3 - 1 | CD VictoriaCD Victoria |
| |
| 19 Mar 23 | r13 | OlanchoOlancho | 1 - 0 | MotaguaMotagua |
| |
| 02 Apr 23 | r14 | MotaguaMotagua | 1 - 3 | CD OlimpiaCD Olimpia |
| |
| 09 Apr 23 | r15 | VidaVida | 0 - 1 | MotaguaMotagua |
| |
| 16 Apr 23 | r16 | MotaguaMotagua | 2 - 2 | Real Sociedad TocoaReal Sociedad |
| |
| 23 Apr 23 | r17 | MotaguaMotagua | 2 - 2 | CD MarathónCD Marathón |
| |
| 29 Apr 23 | r18 | Honduras ProgresoHonduras Prog | 1 - 1 | MotaguaMotagua |
| |
| 04 May 23 | r00 | MotaguaMotagua | 1 - 2 | CD MarathónCD Marathón |
| 07 May 23 | r00 | CD MarathónCD Marathón | 0 - 0 | MotaguaMotagua |
Team 2022-2023 Schedules
CD Olimpia
CD Victoria
Choloma
Génesis
Juticalpa
Lobos UPNFM
Marathón
Motagua
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Real España
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