| 04 Oct 20 | r01  | Honduras ProgresoHonduras Prog | 1 - 1 | CD MarathónCD Marathón |
| |
| 07 Oct 20 | r02 | CD MarathónCD Marathón | 1 - 2 | MotaguaMotagua |
| |
| 11 Oct 20 | r03 | VidaVida | 0 - 1 | CD MarathónCD Marathón |
| |
| 14 Oct 20 | r04 | CD MarathónCD Marathón | 3 - 0 | Real EspañaReal España |
| |
| 18 Oct 20 | r05 | Platense Puerto CortésPlatense Puer | 0 - 1 | CD MarathónCD Marathón |
| |
| 25 Oct 20 | r07 | MotaguaMotagua | 1 - 1 | CD MarathónCD Marathón |
| |
| 28 Oct 20 | r08 | CD MarathónCD Marathón | 0 - 2 | VidaVida |
| |
| 01 Nov 20 | r09 | Real EspañaReal España | 0 - 1 | CD MarathónCD Marathón |
| |
| 14 Nov 20 | r13 | Real de MinasReal de Minas | 2 - 0 | CD MarathónCD Marathón |
| |
| 22 Nov 20 | r10 | CD MarathónCD Marathón | 3 - 0 | Platense Puerto CortésPlatense Puer |
| |
| 25 Nov 20 | r11 | Lobos UPNFMLobos UPNFM | 0 - 2 | CD MarathónCD Marathón |
| |
| 28 Nov 20 | r12 | CD MarathónCD Marathón | 5 - 0 | Real Sociedad TocoaReal Sociedad |
| |
| 05 Dec 20 | r06 | CD MarathónCD Marathón | 4 - 0 | Honduras ProgresoHonduras Prog |
| |
| 12 Dec 20 | r14 | CD MarathónCD Marathón | 1 - 3 | CD OlimpiaCD Olimpia |
| 12 Dec 20 | r14 | CD MarathónCD Marathón | 1 - 3 | CD OlimpiaCD Olimpia |
| |
| 23 Dec 20 | r00 | CD MarathónCD Marathón | 3 - 1 | CD OlimpiaCD Olimpia |
| 28 Dec 20 | r00 | CD OlimpiaCD Olimpia | 1 - 0 | CD MarathónCD Marathón |
| 31 Dec 20 | r00 | MotaguaMotagua | 2 - 0 | CD MarathónCD Marathón |
| 03 Jan 21 | r00 | CD MarathónCD Marathón | 1 - 2 | MotaguaMotagua |
| 15 Jan 21 | r00 | CD OlimpiaCD Olimpia | 2 - 0 | CD MarathónCD Marathón |
| 17 Jan 21 | r00 | CD MarathónCD Marathón | 0 - 1 | CD OlimpiaCD Olimpia |
| |
| 17 Feb 21 | r01 | Honduras ProgresoHonduras Prog | 1 - 1 | CD MarathónCD Marathón |
| |
| 20 Feb 21 | r02 | CD MarathónCD Marathón | 0 - 1 | MotaguaMotagua |
| |
| 24 Feb 21 | r03 | VidaVida | 0 - 1 | CD MarathónCD Marathón |
| |
| 27 Feb 21 | r04 | CD MarathónCD Marathón | 1 - 2 | Real EspañaReal España |
| |
| 03 Mar 21 | r05 | Platense Puerto CortésPlatense Puer | 5 - 3 | CD MarathónCD Marathón |
| |
| 07 Mar 21 | r06 | CD MarathónCD Marathón | 1 - 1 | Honduras ProgresoHonduras Prog |
| |
| 12 Mar 21 | r07 | MotaguaMotagua | 2 - 0 | CD MarathónCD Marathón |
| |
| 17 Mar 21 | r08 | CD MarathónCD Marathón | 1 - 2 | VidaVida |
| |
| 21 Mar 21 | r09 | Real EspañaReal España | 2 - 2 | CD MarathónCD Marathón |
| |
| 03 Apr 21 | r10 | CD MarathónCD Marathón | 1 - 0 | Platense Puerto CortésPlatense Puer |
| |
| 09 Apr 21 | r11 | CD MarathónCD Marathón | 1 - 1 | Lobos UPNFMLobos UPNFM |
| |
| 17 Apr 21 | r12 | Real Sociedad TocoaReal Sociedad | 1 - 1 | CD MarathónCD Marathón |
| |
| 21 Apr 21 | r13 | CD MarathónCD Marathón | 3 - 2 | Real de MinasReal de Minas |
| |
| 28 Apr 21 | r14 | CD OlimpiaCD Olimpia | 2 - 1 | CD MarathónCD Marathón |
Team 2020-2021 Schedules
CD Olimpia
CD Victoria
Choloma
Génesis
Juticalpa
Lobos UPNFM
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Motagua
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