| 19 Jul 25 | r01   | Cobán ImperialCobán Imperia | 0 - 1 | MixcoMixco |
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| 26 Jul 25 | r02 | MixcoMixco | 1 - 0 | ComunicacionesComunicacione |
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| 02 Aug 25 | r03 | MalacatecoMalacateco | 1 - 2 | MixcoMixco |
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| 09 Aug 25 | r04 | MixcoMixco | 2 - 1 | XelajúXelajú |
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| 17 Aug 25 | r05 | Deportivo MictlánDeportivo Mic | 0 - 0 | MixcoMixco |
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| 23 Aug 25 | r06 | AntiguaAntigua | 2 - 1 | MixcoMixco |
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| 30 Aug 25 | r07 | MixcoMixco | 2 - 0 | GuastatoyaGuastatoya |
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| 04 Sep 25 | r08 | MunicipalMunicipal | 3 - 1 | MixcoMixco |
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| 12 Sep 25 | r09 | MixcoMixco | 1 - 0 | MarquenseMarquense |
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| 20 Sep 25 | r11 | MixcoMixco | 2 - 2 | Aurora FCAurora FC |
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| 27 Sep 25 | r12 | MixcoMixco | 1 - 0 | Cobán ImperialCobán Imperia |
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| 04 Oct 25 | r13 | ComunicacionesComunicacione | 0 - 1 | MixcoMixco |
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| 12 Oct 25 | r14 | MixcoMixco | 4 - 1 | MalacatecoMalacateco |
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| 18 Oct 25 | r15 | XelajúXelajú | 1 - 2 | MixcoMixco |
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| 22 Oct 25 | r10 | AchuapaAchuapa | 3 - 2 | MixcoMixco |
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| 25 Oct 25 | r16 | MixcoMixco | 2 - 1 | Deportivo MictlánDeportivo Mic |
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| 01 Nov 25 | r17 | MixcoMixco | 0 - 1 | AntiguaAntigua |
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| 06 Nov 25 | r18 | GuastatoyaGuastatoya | 1 - 0 | MixcoMixco |
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| 09 Nov 25 | r19 | MixcoMixco | 1 - 0 | MunicipalMunicipal |
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| 16 Nov 25 | r20 | MarquenseMarquense | 1 - 2 | MixcoMixco |
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| 22 Nov 25 | r21 | MixcoMixco | 5 - 1 | AchuapaAchuapa |
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| 30 Nov 25 | r22 | Aurora FCAurora FC | 1 - 0 | MixcoMixco |
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| 07 Dec 25 | r00 | AchuapaAchuapa | 3 - 2 | MixcoMixco |
| 11 Dec 25 | r00  | MixcoMixco | 0 - 0 | AchuapaAchuapa |
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| 23 Jan 26 | r01 | GuastatoyaGuastatoya | 2 - 0 | MixcoMixco |
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| 25 Jan 26 | r02 | MixcoMixco | 1 - 0 | MalacatecoMalacateco |
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| 28 Jan 26 | r03 | AchuapaAchuapa | 2 - 0 | MixcoMixco |
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| 31 Jan 26 | r04 | MixcoMixco | 1 - 1 | Cobán ImperialCobán Imperia |
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| 09 Feb 26 | r05 | AntiguaAntigua | 1 - 2 | MixcoMixco |
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| 14 Feb 26 | r06 | MixcoMixco | 2 - 2 | ComunicacionesComunicacione |
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| 20 Feb 26 | r07 | MarquenseMarquense | 2 - 1 | MixcoMixco |
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| 23 Feb 26 | r08 | XelajúXelajú | 2 - 1 | MixcoMixco |
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| 26 Feb 26 | r09 | MixcoMixco | 2 - 2 | Deportivo MictlánDeportivo Mic |
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| 01 Mar 26 | r10 | Aurora FCAurora FC | 1 - 1 | MixcoMixco |
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| 04 Mar 26 | r11 | MixcoMixco | 1 - 0 | MunicipalMunicipal |
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| 07 Mar 26 | r12 | MixcoMixco | 1 - 0 | GuastatoyaGuastatoya |
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| 15 Mar 26 | r13 | MalacatecoMalacateco | 1 - 2 | MixcoMixco |
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| 18 Mar 26 | r14 | MixcoMixco | 1 - 0 | AchuapaAchuapa |
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| 21 Mar 26 | r15 | Cobán ImperialCobán Imperia | 1 - 1 | MixcoMixco |
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| 28 Mar 26 | r16 | MixcoMixco | 2 - 1 | AntiguaAntigua |
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| 02 Apr 26 | r17 | ComunicacionesComunicacione | 1 - 0 | MixcoMixco |
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| 07 Apr 26 | r18 | MixcoMixco | 2 - 1 | MarquenseMarquense |
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| 11 Apr 26 | r19 | MixcoMixco | 3 - 1 | XelajúXelajú |
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| 16 Apr 26 | r20 | Deportivo MictlánDeportivo Mic | 2 - 2 | MixcoMixco |
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| 19 Apr 26 | r21 | MixcoMixco | 4 - 0 | Aurora FCAurora FC |
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| 26 Apr 26 | r22 | MunicipalMunicipal | 3 - 0 | MixcoMixco |
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| 29 Apr 26 | r00 | Cobán ImperialCobán Imperia | 2 - 0 | MixcoMixco |
| 02 May 26 | r00 | MixcoMixco | 2 - 0 | Cobán ImperialCobán Imperia |
| 06 May 26 | r00 | MixcoMixco | 0 - 2 | MunicipalMunicipal |
| 10 May 26 | r00 | MunicipalMunicipal | 5 - 0 | MixcoMixco |
Team 2025-2026 Schedules
Achuapa
Antigua
Aurora FC
Cobán Imperial
Comunicaciones
Deportivo Mictlán
Guastatoya
Malacateco
Mixco
Municipal
Xelajú
Xinabajul
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