| 26 Jul 20 | r01  | MalacatecoMalacateco | - | CD GuastatoyaCD Guastatoya |
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| 09 Aug 20 | r03 | ComunicacionesComunicacione | - | CD GuastatoyaCD Guastatoya |
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| 12 Aug 20 | r04 | CD GuastatoyaCD Guastatoya | - | IztapaIztapa |
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| 16 Aug 20 | r05 | Cobán ImperialCobán Imperia | - | CD GuastatoyaCD Guastatoya |
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| 23 Aug 20 | r06 | CD GuastatoyaCD Guastatoya | - | SanarateSanarate |
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| 30 Aug 20 | r01 | CD GuastatoyaCD Guastatoya | 1 - 1 | SanarateSanarate |
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| 05 Sep 20 | r02 | MunicipalMunicipal | 2 - 1 | CD GuastatoyaCD Guastatoya |
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| 13 Sep 20 | r03 | CD GuastatoyaCD Guastatoya | 2 - 2 | AchuapaAchuapa |
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| 16 Sep 20 | r09 | MunicipalMunicipal | - | CD GuastatoyaCD Guastatoya |
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| 20 Sep 20 | r10 | CD GuastatoyaCD Guastatoya | - | Antigua GFCAntigua GFC |
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| 21 Sep 20 | r04 | SacachispasSacachispas | 2 - 1 | CD GuastatoyaCD Guastatoya |
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| 23 Sep 20 | r11 | XelajúXelajú | - | CD GuastatoyaCD Guastatoya |
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| 27 Sep 20 | r12 | CD GuastatoyaCD Guastatoya | - | MalacatecoMalacateco |
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| 27 Sep 20 | r05 | CD GuastatoyaCD Guastatoya | 1 - 1 | Cobán ImperialCobán Imperia |
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| 10 Oct 20 | r07 | CD GuastatoyaCD Guastatoya | 0 - 0 | MunicipalMunicipal |
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| 14 Oct 20 | r06 | SanarateSanarate | 1 - 2 | CD GuastatoyaCD Guastatoya |
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| 15 Oct 20 | r14 | CD GuastatoyaCD Guastatoya | - | ComunicacionesComunicacione |
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| 18 Oct 20 | r15 | IztapaIztapa | - | CD GuastatoyaCD Guastatoya |
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| 18 Oct 20 | r08 | AchuapaAchuapa | 0 - 1 | CD GuastatoyaCD Guastatoya |
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| 25 Oct 20 | r16 | CD GuastatoyaCD Guastatoya | - | Cobán ImperialCobán Imperia |
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| 25 Oct 20 | r09 | CD GuastatoyaCD Guastatoya | 3 - 3 | SacachispasSacachispas |
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| 31 Oct 20 | r10 | Cobán ImperialCobán Imperia | 3 - 1 | CD GuastatoyaCD Guastatoya |
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| 01 Nov 20 | r17 | SanarateSanarate | - | CD GuastatoyaCD Guastatoya |
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| 04 Nov 20 | r18 | CD GuastatoyaCD Guastatoya | - | Santa LuciaSanta Lucia |
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| 07 Nov 20 | r11 | Santa LuciaSanta Lucia | 0 - 0 | CD GuastatoyaCD Guastatoya |
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| 18 Nov 20 | r12 | CD GuastatoyaCD Guastatoya | 2 - 0 | XelajúXelajú |
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| 22 Nov 20 | r20 | CD GuastatoyaCD Guastatoya | - | MunicipalMunicipal |
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| 22 Nov 20 | r13 | MalacatecoMalacateco | 2 - 0 | CD GuastatoyaCD Guastatoya |
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| 29 Nov 20 | r21 | Antigua GFCAntigua GFC | - | CD GuastatoyaCD Guastatoya |
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| 29 Nov 20 | r14 | CD GuastatoyaCD Guastatoya | 2 - 2 | Antigua GFCAntigua GFC |
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| 06 Dec 20 | r22 | CD GuastatoyaCD Guastatoya | - | XelajúXelajú |
| |
| 06 Dec 20 | r15 | ComunicacionesComunicacione | 0 - 0 | CD GuastatoyaCD Guastatoya |
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| 28 Dec 20 | r16 | CD GuastatoyaCD Guastatoya | 2 - 0 | IztapaIztapa |
| |
| 31 Dec 20 | r00 | CD GuastatoyaCD Guastatoya | 0 - 0 | Cobán ImperialCobán Imperia |
| 03 Jan 21 | r00 | Cobán ImperialCobán Imperia | 1 - 2 | CD GuastatoyaCD Guastatoya |
| 28 Jan 21 | r00 | CD GuastatoyaCD Guastatoya | 1 - 1 | XelajúXelajú |
| 31 Jan 21 | r00 | XelajúXelajú | 0 - 2 | CD GuastatoyaCD Guastatoya |
| 04 Feb 21 | r00 | CD GuastatoyaCD Guastatoya | 2 - 1 | MunicipalMunicipal |
| 07 Feb 21 | r00 | MunicipalMunicipal | 1 - 1 | CD GuastatoyaCD Guastatoya |
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| 21 Feb 21 | r01 | CD GuastatoyaCD Guastatoya | 5 - 1 | SanarateSanarate |
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| 27 Feb 21 | r02 | MunicipalMunicipal | 0 - 1 | CD GuastatoyaCD Guastatoya |
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| 03 Mar 21 | r03 | CD GuastatoyaCD Guastatoya | 3 - 0 | AchuapaAchuapa |
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| 07 Mar 21 | r04 | SacachispasSacachispas | 0 - 1 | CD GuastatoyaCD Guastatoya |
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| 10 Mar 21 | r05 | CD GuastatoyaCD Guastatoya | 1 - 1 | Cobán ImperialCobán Imperia |
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| 14 Mar 21 | r06 | SanarateSanarate | 3 - 2 | CD GuastatoyaCD Guastatoya |
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| 01 Apr 21 | r07 | CD GuastatoyaCD Guastatoya | 0 - 0 | MunicipalMunicipal |
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| 04 Apr 21 | r08 | AchuapaAchuapa | 1 - 0 | CD GuastatoyaCD Guastatoya |
| |
| 07 Apr 21 | r09 | CD GuastatoyaCD Guastatoya | 3 - 0 | SacachispasSacachispas |
| |
| 10 Apr 21 | r10 | Cobán ImperialCobán Imperia | 0 - 1 | CD GuastatoyaCD Guastatoya |
| |
| 14 Apr 21 | r11 | CD GuastatoyaCD Guastatoya | 1 - 1 | Santa LuciaSanta Lucia |
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| 18 Apr 21 | r12 | XelajúXelajú | 1 - 1 | CD GuastatoyaCD Guastatoya |
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| 21 Apr 21 | r13 | CD GuastatoyaCD Guastatoya | 0 - 0 | MalacatecoMalacateco |
| |
| 25 Apr 21 | r14 | Antigua GFCAntigua GFC | 0 - 0 | CD GuastatoyaCD Guastatoya |
| |
| 28 Apr 21 | r15 | CD GuastatoyaCD Guastatoya | 2 - 0 | ComunicacionesComunicacione |
| |
| 02 May 21 | r16 | IztapaIztapa | 2 - 2 | CD GuastatoyaCD Guastatoya |
| |
| 05 May 21 | r00 | SanarateSanarate | 2 - 0 | CD GuastatoyaCD Guastatoya |
| 08 May 21 | r00 | CD GuastatoyaCD Guastatoya | 4 - 1 | SanarateSanarate |
| 14 May 21 | r00 | Santa LuciaSanta Lucia | 1 - 0 | CD GuastatoyaCD Guastatoya |
| 16 May 21 | r00 | CD GuastatoyaCD Guastatoya | 1 - 2 | Santa LuciaSanta Lucia |
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