| 15 Aug 20 | r01  | GuadalupeGuadalupe | 2 - 2 | Santos de GuápilesSantos de Guá |
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| 23 Aug 20 | r02  | AlajuelenseAlajuelense | 0 - 1 | GuadalupeGuadalupe |
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| 30 Aug 20 | r03 | Pérez ZeledónPérez Zeledón | 3 - 2 | GuadalupeGuadalupe |
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| 02 Sep 20 | r04 | GuadalupeGuadalupe | 1 - 0 | GreciaGrecia |
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| 05 Sep 20 | r05 | GuadalupeGuadalupe | 2 - 3 | CS HeredianoCS Herediano |
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| 13 Sep 20 | r06 | GreciaGrecia | 0 - 1 | GuadalupeGuadalupe |
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| 20 Sep 20 | r07 | CS HeredianoCS Herediano | 3 - 1 | GuadalupeGuadalupe |
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| 27 Sep 20 | r08 | GuadalupeGuadalupe | 4 - 1 | Pérez ZeledónPérez Zeledón |
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| 04 Oct 20 | r09 | GuadalupeGuadalupe | 1 - 2 | AlajuelenseAlajuelense |
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| 30 Oct 20 | r11 | GuadalupeGuadalupe | 1 - 0 | CartaginésCartaginés |
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| 01 Nov 20 | r12 | JicaralJicaral | 3 - 1 | GuadalupeGuadalupe |
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| 05 Nov 20 | r10 | Santos de GuápilesSantos de Guá | 1 - 1 | GuadalupeGuadalupe |
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| 08 Nov 20 | r13 | GuadalupeGuadalupe | 2 - 2 | Sporting San JoseSporting San |
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| 11 Nov 20 | r14 | LimónLimón | 2 - 1 | GuadalupeGuadalupe |
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| 15 Nov 20 | r15 | Deportivo SaprissaDeportivo Sap | 5 - 1 | GuadalupeGuadalupe |
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| 06 Dec 20 | r16 | GuadalupeGuadalupe | 3 - 0 | AD San CarlosAD San Carlos |
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| 13 Jan 21 | r01 | GuadalupeGuadalupe | 3 - 0 | LimónLimón |
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| 17 Jan 21 | r02 | CartaginésCartaginés | 2 - 1 | GuadalupeGuadalupe |
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| 20 Jan 21 | r03 | AD San CarlosAD San Carlos | 1 - 0 | GuadalupeGuadalupe |
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| 26 Jan 21 | r04 | GuadalupeGuadalupe | 2 - 2 | Deportivo SaprissaDeportivo Sap |
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| 01 Feb 21 | r05 | Santos de GuápilesSantos de Guá | 2 - 2 | GuadalupeGuadalupe |
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| 04 Feb 21 | r06 | CS HeredianoCS Herediano | 2 - 2 | GuadalupeGuadalupe |
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| 06 Feb 21 | r07 | GuadalupeGuadalupe | 0 - 0 | Sporting San JoseSporting San |
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| 16 Feb 21 | r08 | Pérez ZeledónPérez Zeledón | 1 - 3 | GuadalupeGuadalupe |
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| 21 Feb 21 | r09 | GuadalupeGuadalupe | 1 - 1 | GreciaGrecia |
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| 27 Feb 21 | r10 | JicaralJicaral | 3 - 2 | GuadalupeGuadalupe |
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| 04 Mar 21 | r11 | GuadalupeGuadalupe | 1 - 3 | AlajuelenseAlajuelense |
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| 06 Mar 21 | r12 | LimónLimón | 1 - 7 | GuadalupeGuadalupe |
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| 13 Mar 21 | r13 | GuadalupeGuadalupe | 0 - 3 | CartaginésCartaginés |
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| 20 Mar 21 | r14 | GuadalupeGuadalupe | 1 - 2 | AD San CarlosAD San Carlos |
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| 01 Apr 21 | r15 | Deportivo SaprissaDeportivo Sap | 1 - 1 | GuadalupeGuadalupe |
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| 04 Apr 21 | r16 | GuadalupeGuadalupe | 2 - 4 | Santos de GuápilesSantos de Guá |
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| 11 Apr 21 | r17 | GuadalupeGuadalupe | 2 - 2 | CS HeredianoCS Herediano |
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| 18 Apr 21 | r18 | Sporting San JoseSporting San | 0 - 3 | GuadalupeGuadalupe |
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| 22 Apr 21 | r19 | GuadalupeGuadalupe | 0 - 1 | Pérez ZeledónPérez Zeledón |
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| 25 Apr 21 | r20 | GreciaGrecia | 0 - 0 | GuadalupeGuadalupe |
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| 02 May 21 | r21 | GuadalupeGuadalupe | 0 - 0 | JicaralJicaral |
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| 13 May 21 | r22 | AlajuelenseAlajuelense | 0 - 0 | GuadalupeGuadalupe |
Team 2020-2021 Schedules
AD San Carlos
Alajuelense
Cartaginés
Deportivo Saprissa
Guadalupe
Herediano
Municipal Liberia
Pérez Zeledón
Puntarenas
Sporting San Jose
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