| 17 Jul 25 | r01  | ManaguaManagua | 4 - 2 | ART JalapaART Jalapa |
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| 22 Jul 25 | r02 | SébacoSébaco | 1 - 0 | ManaguaManagua |
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| 26 Jul 25 | r03 | ManaguaManagua | 1 - 1 | Rancho SantanaRancho Santan |
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| 03 Aug 25 | r04 | Real MadrizReal Madriz | 0 - 1 | ManaguaManagua |
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| 11 Aug 25 | r05 | Real EstelíReal Estelí | 1 - 0 | ManaguaManagua |
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| 24 Aug 25 | r07 | MatagalpaMatagalpa | 1 - 2 | ManaguaManagua |
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| 14 Sep 25 | r09 | ManaguaManagua | 2 - 0 | DiriangénDiriangén |
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| 18 Sep 25 | r08 | ManaguaManagua | 1 - 0 | UNAN ManaguaUNAN Managua |
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| 20 Sep 25 | r10 | ART JalapaART Jalapa | 2 - 1 | ManaguaManagua |
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| 25 Sep 25 | r06 | ManaguaManagua | 1 - 1 | Walter FerrettiWalter Ferret |
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| 29 Sep 25 | r11 | ManaguaManagua | 4 - 2 | SébacoSébaco |
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| 16 Oct 25 | r13 | ManaguaManagua | 2 - 0 | Real MadrizReal Madriz |
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| 19 Oct 25 | r12 | Rancho SantanaRancho Santan | 0 - 5 | ManaguaManagua |
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| 23 Oct 25 | r14 | ManaguaManagua | 2 - 1 | Real EstelíReal Estelí |
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| 27 Oct 25 | r15 | Walter FerrettiWalter Ferret | 1 - 0 | ManaguaManagua |
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| 02 Nov 25 | r16 | ManaguaManagua | 3 - 0 | MatagalpaMatagalpa |
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| 05 Nov 25 | r17  | UNAN ManaguaUNAN Managua | 0 - 3 | ManaguaManagua |
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| 23 Nov 25 | r18 | DiriangénDiriangén | 1 - 1 | ManaguaManagua |
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| 01 Dec 25 | r00 | Real EstelíReal Estelí | 0 - 2 | ManaguaManagua |
| 07 Dec 25 | r00 | ManaguaManagua | 0 - 2 | Real EstelíReal Estelí |
| 14 Dec 25 | r00 | ManaguaManagua | 0 - 0 | DiriangénDiriangén |
| 21 Dec 25 | r00 | DiriangénDiriangén | 1 - 0 | ManaguaManagua |
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| 17 Jan 26 | r01 | ART JalapaART Jalapa | 2 - 0 | ManaguaManagua |
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| 25 Jan 26 | r02 | Real EstelíReal Estelí | 6 - 3 | ManaguaManagua |
| 26 Jan 26 | r02 | ManaguaManagua | 1 - 0 | SébacoSébaco |
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| 01 Feb 26 | r03 | Rancho SantanaRancho Santan | 1 - 1 | ManaguaManagua |
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| 04 Feb 26 | r04 | ManaguaManagua | 2 - 0 | Real MadrizReal Madriz |
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| 08 Feb 26 | r05 | ManaguaManagua | 0 - 2 | Real EstelíReal Estelí |
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| 13 Feb 26 | r06 | Walter FerrettiWalter Ferret | 1 - 0 | ManaguaManagua |
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| 16 Feb 26 | r07 | ManaguaManagua | 1 - 1 | MatagalpaMatagalpa |
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| 20 Feb 26 | r08 | UNAN ManaguaUNAN Managua | 3 - 1 | ManaguaManagua |
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| 22 Feb 26 | r09 | DiriangénDiriangén | 1 - 1 | ManaguaManagua |
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| 25 Feb 26 | r10 | ManaguaManagua | 1 - 0 | ART JalapaART Jalapa |
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| 01 Mar 26 | r11 | SébacoSébaco | 0 - 2 | ManaguaManagua |
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| 05 Mar 26 | r12 | ManaguaManagua | 1 - 0 | Rancho SantanaRancho Santan |
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| 08 Mar 26 | r13 | Real MadrizReal Madriz | 1 - 2 | ManaguaManagua |
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| 09 Apr 26 | r14 | Real EstelíReal Estelí | 2 - 1 | ManaguaManagua |
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| 13 Apr 26 | r15 | ManaguaManagua | 1 - 1 | Walter FerrettiWalter Ferret |
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| 16 Apr 26 | r16 | MatagalpaMatagalpa | 1 - 2 | ManaguaManagua |
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| 19 Apr 26 | r17 | ManaguaManagua | 1 - 1 | UNAN ManaguaUNAN Managua |
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| 26 Apr 26 | r18 | ManaguaManagua | 4 - 1 | DiriangénDiriangén |
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| 30 Apr 26 | r00 | ManaguaManagua | 2 - 4 | MatagalpaMatagalpa |
Team 2025-2026 Schedules
ART Jalapa
Diriangén
Managua
Matagalpa
Rancho Santana
Real Estelí
San Marcos
Sébaco
UNAN Managua
Walter Ferretti
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