| 21 Aug 21 | r01        | Cape Town CityCape Town Cit | 0 - 0 | SuperSport UnitedSuperSport Un |
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| 25 Aug 21 | r02        | SuperSport UnitedSuperSport Un | 3 - 1 | Golden ArrowsGolden Arrows |
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| 14 Sep 21 | r03        | AmazuluAmazulu | 0 - 0 | SuperSport UnitedSuperSport Un |
| 19 Sep 21 | r03        | Moroka SwallowsMoroka Swallo | 0 - 3 | SuperSport UnitedSuperSport Un |
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| 25 Sep 21 | r04        | SuperSport UnitedSuperSport Un | 2 - 1 | Maritzburg UnitedMaritzburg Un |
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| 02 Oct 21 | r05        | Chippa UnitedChippa United | 0 - 0 | SuperSport UnitedSuperSport Un |
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| 16 Oct 21 | r06        | SuperSport UnitedSuperSport Un | 2 - 0 | Baroka FCBaroka FC |
| 24 Oct 21 | r06        | SuperSport UnitedSuperSport Un | 1 - 2 | Kaizer ChiefsKaizer Chiefs |
| |
| 02 Nov 21 | r07        | Bloemfontein CelticBloemfontein | 2 - 1 | SuperSport UnitedSuperSport Un |
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| 05 Nov 21 | r08        | SuperSport UnitedSuperSport Un | 2 - 1 | TS GalaxyTS Galaxy |
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| 20 Nov 21 | r09        | SuperSport UnitedSuperSport Un | 1 - 2 | TT MadzivhandilaTT Madzivhand |
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| 24 Nov 21 | r10        | Mamelodi SundownsMamelodi Sund | 2 - 2 | SuperSport UnitedSuperSport Un |
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| 05 Dec 21 | r11        | SuperSport UnitedSuperSport Un | 0 - 1 | Sekhukhune UnitedSekhukhune Un |
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| 08 Dec 21 | r12        | StellenboschStellenbosch | 0 - 1 | SuperSport UnitedSuperSport Un |
| 11 Dec 21 | r12        | SuperSport UnitedSuperSport Un | 0 - 1 | Mamelodi SundownsMamelodi Sund |
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| 18 Dec 21 | r13        | Sekhukhune UnitedSekhukhune Un | 0 - 0 | SuperSport UnitedSuperSport Un |
| |
| 22 Dec 21 | r14        | SuperSport UnitedSuperSport Un | 3 - 2 | Cape Town CityCape Town Cit |
| |
| 15 Feb 22 | r15        | Maritzburg UnitedMaritzburg Un | 2 - 1 | SuperSport UnitedSuperSport Un |
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| 27 Feb 22 | r16        | SuperSport UnitedSuperSport Un | 0 - 2 | Bloemfontein CelticBloemfontein |
| |
| 05 Mar 22 | r17        | SuperSport UnitedSuperSport Un | 2 - 0 | AmazuluAmazulu |
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| 16 Mar 22 | r18        | Orlando PiratesOrlando Pirat | 3 - 2 | SuperSport UnitedSuperSport Un |
| 19 Mar 22 | r18        | TS GalaxyTS Galaxy | 1 - 1 | SuperSport UnitedSuperSport Un |
| |
| 02 Apr 22 | r19        | Golden ArrowsGolden Arrows | 3 - 2 | SuperSport UnitedSuperSport Un |
| 05 Apr 22 | r19        | SuperSport UnitedSuperSport Un | 1 - 1 | Chippa UnitedChippa United |
| |
| 16 Apr 22 | r20        | Kaizer ChiefsKaizer Chiefs | 0 - 1 | SuperSport UnitedSuperSport Un |
| |
| 23 Apr 22 | r21        | TT MadzivhandilaTT Madzivhand | 0 - 0 | SuperSport UnitedSuperSport Un |
| |
| 03 May 22 | r22        | SuperSport UnitedSuperSport Un | 0 - 0 | StellenboschStellenbosch |
| 06 May 22 | r22        | SuperSport UnitedSuperSport Un | 2 - 2 | Moroka SwallowsMoroka Swallo |
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| 14 May 22 | r23        | Baroka FCBaroka FC | 3 - 1 | SuperSport UnitedSuperSport Un |
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| 30 May 22 | r24        | SuperSport UnitedSuperSport Un | 2 - 0 | Orlando PiratesOrlando Pirat |