| 07 Aug 21 | r01  | Newry City AFCNewry City AF | 3 - 0 | KnockbredaKnockbreda |
| |
| 10 Aug 21 | r15 | Newry City AFCNewry City AF | 3 - 2 | H and W WeldersH and W Welde |
| |
| 14 Aug 21 | r03 | Newry City AFCNewry City AF | 5 - 1 | InstituteInstitute |
| |
| 21 Aug 21 | r04 | DergviewDergview | 0 - 2 | Newry City AFCNewry City AF |
| |
| 27 Aug 21 | r05 | Newry City AFCNewry City AF | 2 - 1 | ArdsArds |
| |
| 04 Sep 21 | r06 | Queens UniversityQueens Univer | 0 - 2 | Newry City AFCNewry City AF |
| |
| 11 Sep 21 | r07 | Newry City AFCNewry City AF | 0 - 3 | Ballinamallard UnitedBallinamallar |
| |
| 18 Sep 21 | r08 | Ballyclare ComradesBallyclare Co | 1 - 0 | Newry City AFCNewry City AF |
| |
| 25 Sep 21 | r09 | Newry City AFCNewry City AF | 1 - 1 | DundelaDundela |
| |
| 01 Oct 21 | r10 | Annagh UnitedAnnagh United | 0 - 3 | Newry City AFCNewry City AF |
| |
| 09 Oct 21 | r11 | Newry City AFCNewry City AF | 1 - 1 | LoughgallLoughgall |
| |
| 16 Oct 21 | r12 | InstituteInstitute | 1 - 2 | Newry City AFCNewry City AF |
| |
| 22 Oct 21 | r13 | Newry City AFCNewry City AF | 1 - 2 | DergviewDergview |
| 22 Oct 21 | r13 | Newry City AFCNewry City AF | 1 - 2 | DergviewDergview |
| |
| 29 Oct 21 | r14 | ArdsArds | 1 - 1 | Newry City AFCNewry City AF |
| 29 Oct 21 | r14 | ArdsArds | 1 - 1 | Newry City AFCNewry City AF |
| |
| 06 Nov 21 | r02 | H and W WeldersH and W Welde | 1 - 2 | Newry City AFCNewry City AF |
| |
| 13 Nov 21 | r16 | Newry City AFCNewry City AF | 2 - 0 | Ballinamallard UnitedBallinamallar |
| |
| 20 Nov 21 | r17 | KnockbredaKnockbreda | 0 - 2 | Newry City AFCNewry City AF |
| |
| 26 Nov 21 | r18 | DundelaDundela | 2 - 2 | Newry City AFCNewry City AF |
| |
| 03 Dec 21 | r19 | Newry City AFCNewry City AF | 2 - 0 | Annagh UnitedAnnagh United |
| |
| 11 Dec 21 | r20 | LoughgallLoughgall | 1 - 3 | Newry City AFCNewry City AF |
| |
| 18 Dec 21 | r21 | Queens UniversityQueens Univer | 0 - 1 | Newry City AFCNewry City AF |
| |
| 27 Dec 21 | r22 | Newry City AFCNewry City AF | 0 - 1 | Ballyclare ComradesBallyclare Co |
| |
| 01 Jan 22 | r23 | InstituteInstitute | 0 - 0 | Newry City AFCNewry City AF |
| |
| 14 Jan 22 | r24 | Newry City AFCNewry City AF | 1 - 2 | H and W WeldersH and W Welde |
| |
| 22 Jan 22 | r25 | Ballinamallard UnitedBallinamallar | 0 - 2 | Newry City AFCNewry City AF |
| |
| 28 Jan 22 | r26 | Newry City AFCNewry City AF | 1 - 0 | DundelaDundela |
| |
| 11 Feb 22 | r27 | DergviewDergview | 0 - 2 | Newry City AFCNewry City AF |
| |
| 25 Feb 22 | r29 | Newry City AFCNewry City AF | 0 - 3 | Annagh UnitedAnnagh United |
| |
| 08 Mar 22 | r28 | Newry City AFCNewry City AF | 5 - 1 | KnockbredaKnockbreda |
| |
| 12 Mar 22 | r31 | Newry City AFCNewry City AF | 4 - 0 | ArdsArds |
| |
| 15 Mar 22 | r30 | LoughgallLoughgall | 1 - 0 | Newry City AFCNewry City AF |
| |
| 19 Mar 22 | r32 | Newry City AFCNewry City AF | 0 - 0 | Queens UniversityQueens Univer |
| |
| 26 Mar 22 | r33 | Ballyclare ComradesBallyclare Co | 1 - 5 | Newry City AFCNewry City AF |
| |
| 09 Apr 22 | r01 | Annagh UnitedAnnagh United | 1 - 1 | Newry City AFCNewry City AF |
| |
| 16 Apr 22 | r02 | Newry City AFCNewry City AF | 0 - 2 | LoughgallLoughgall |
| |
| 19 Apr 22 | r03 | H and W WeldersH and W Welde | 0 - 3 | Newry City AFCNewry City AF |
| |
| 23 Apr 22 | r04 | Ballinamallard UnitedBallinamallar | 1 - 0 | Newry City AFCNewry City AF |
| |
| 30 Apr 22 | r05 | Newry City AFCNewry City AF | 6 - 1 | DergviewDergview |
Team 2021-2022 Schedules
Annagh United
Ards
Armagh City
Ballinamallard United
Dundela
Glenavon
Harland and Wolff Welders
Institute
Loughgall
Moyola Park
Newington
Newry City
Queen's University Belfast
Rathfriland Rangers
Strabane Athletic
Warrenpoint Town
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