| 03 Sep 21 | r01  | Trat FCTrat FC | 2 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 04 Sep 21 | r01 | Muangkan UnitedMuangkan Unit | 1 - 1 | Lampang FCLampang FC |
| 04 Sep 21 | r01 | ChainatChainat | 0 - 0 | Raj PrachaRaj Pracha |
| 04 Sep 21 | r01 | Chiangmai FCChiangmai FC | 2 - 1 | Rayong FCRayong FC |
| 04 Sep 21 | r01 | Ranong UnitedRanong United | 3 - 3 | Udon ThaniUdon Thani |
| 05 Sep 21 | r01 | Sukhothai FCSukhothai FC | 5 - 0 | Ayutthaya FCAyutthaya FC |
| 05 Sep 21 | r01 | Phrae UnitedPhrae United | 4 - 0 | Navy FCNavy FC |
| 05 Sep 21 | r01 | KhonkaenKhonkaen | 0 - 2 | Customs UnitedCustoms Unite |
| 05 Sep 21 | r01 | Lamphun WarriorLamphun Warri | 1 - 0 | Kasetsart FCKasetsart FC |
| |
| 10 Sep 21 | r02 | Ayutthaya FCAyutthaya FC | 5 - 3 | ChainatChainat |
| 11 Sep 21 | r02 | Kasetsart FCKasetsart FC | 1 - 0 | Ranong UnitedRanong United |
| 11 Sep 21 | r02 | Customs UnitedCustoms Unite | 1 - 1 | Lamphun WarriorLamphun Warri |
| 11 Sep 21 | r02 | Udon ThaniUdon Thani | 0 - 0 | Phrae UnitedPhrae United |
| 11 Sep 21 | r02 | Navy FCNavy FC | 0 - 3 | Trat FCTrat FC |
| 11 Sep 21 | r02 | Sukhothai FCSukhothai FC | 3 - 2 | KhonkaenKhonkaen |
| 12 Sep 21 | r02 | Raj PrachaRaj Pracha | 0 - 3 | Chiangmai FCChiangmai FC |
| 12 Sep 21 | r02 | Nakhon Pathom UnitedNakhon Pathom | 1 - 1 | Lampang FCLampang FC |
| 12 Sep 21 | r02 | Rayong FCRayong FC | 3 - 2 | Muangkan UnitedMuangkan Unit |
| |
| 15 Sep 21 | r19 | Kasetsart FCKasetsart FC | 0 - 0 | Chiangmai FCChiangmai FC |
| |
| 15 Sep 21 | r03 | Muangkan UnitedMuangkan Unit | 2 - 1 | Ayutthaya FCAyutthaya FC |
| 15 Sep 21 | r03 | Nakhon Pathom UnitedNakhon Pathom | 1 - 1 | Raj PrachaRaj Pracha |
| 15 Sep 21 | r03 | Trat FCTrat FC | 4 - 3 | Sukhothai FCSukhothai FC |
| |
| 15 Sep 21 | r19 | Navy FCNavy FC | 0 - 3 | Lampang FCLampang FC |
| |
| 15 Sep 21 | r03 | Lamphun WarriorLamphun Warri | 2 - 1 | KhonkaenKhonkaen |
| 15 Sep 21 | r03 | ChainatChainat | 1 - 2 | Udon ThaniUdon Thani |
| 15 Sep 21 | r03 | Ranong UnitedRanong United | 3 - 3 | Customs UnitedCustoms Unite |
| 15 Sep 21 | r03 | Phrae UnitedPhrae United | 2 - 0 | Rayong FCRayong FC |
| |
| 18 Sep 21 | r04 | Kasetsart FCKasetsart FC | 1 - 2 | Lampang FCLampang FC |
| 18 Sep 21 | r04 | Raj PrachaRaj Pracha | 1 - 1 | Trat FCTrat FC |
| 18 Sep 21 | r04 | Sukhothai FCSukhothai FC | 2 - 1 | Lamphun WarriorLamphun Warri |
| 18 Sep 21 | r04 | Udon ThaniUdon Thani | 3 - 1 | Muangkan UnitedMuangkan Unit |
| 19 Sep 21 | r04 | Customs UnitedCustoms Unite | 1 - 3 | ChainatChainat |
| 19 Sep 21 | r04 | Navy FCNavy FC | 2 - 3 | Nakhon Pathom UnitedNakhon Pathom |
| 19 Sep 21 | r04 | Rayong FCRayong FC | 0 - 1 | Ranong UnitedRanong United |
| 19 Sep 21 | r04 | Phrae UnitedPhrae United | 2 - 1 | Ayutthaya FCAyutthaya FC |
| 19 Sep 21 | r04 | Ayutthaya FCAyutthaya FC | 2 - 1 | Phrae UnitedPhrae United |
| 19 Sep 21 | r04 | KhonkaenKhonkaen | 1 - 1 | Chiangmai FCChiangmai FC |
| |
| 25 Sep 21 | r05 | Ranong UnitedRanong United | 3 - 2 | Lamphun WarriorLamphun Warri |
| 25 Sep 21 | r05 | Phrae UnitedPhrae United | 2 - 1 | KhonkaenKhonkaen |
| 25 Sep 21 | r05 | ChainatChainat | 2 - 2 | Sukhothai FCSukhothai FC |
| 25 Sep 21 | r05 | Navy FCNavy FC | 1 - 1 | Raj PrachaRaj Pracha |
| 26 Sep 21 | r05 | Nakhon Pathom UnitedNakhon Pathom | 2 - 2 | Udon ThaniUdon Thani |
| 26 Sep 21 | r05 | Trat FCTrat FC | 4 - 0 | Ayutthaya FCAyutthaya FC |
| 26 Sep 21 | r05 | Muangkan UnitedMuangkan Unit | 1 - 2 | Kasetsart FCKasetsart FC |
| 26 Sep 21 | r05 | Chiangmai FCChiangmai FC | 1 - 2 | Customs UnitedCustoms Unite |
| |
| 02 Oct 21 | r06 | Raj PrachaRaj Pracha | 0 - 0 | Phrae UnitedPhrae United |
| 02 Oct 21 | r06 | Navy FCNavy FC | 0 - 1 | Rayong FCRayong FC |
| 02 Oct 21 | r06 | Rayong FCRayong FC | 0 - 1 | Navy FCNavy FC |
| 02 Oct 21 | r06 | Sukhothai FCSukhothai FC | 4 - 1 | Chiangmai FCChiangmai FC |
| 02 Oct 21 | r06 | Lamphun WarriorLamphun Warri | 1 - 2 | Trat FCTrat FC |
| 02 Oct 21 | r06 | KhonkaenKhonkaen | 1 - 0 | Ranong UnitedRanong United |
| 03 Oct 21 | r06 | Kasetsart FCKasetsart FC | 0 - 4 | ChainatChainat |
| 03 Oct 21 | r06 | Ayutthaya FCAyutthaya FC | 2 - 2 | Nakhon Pathom UnitedNakhon Pathom |
| 03 Oct 21 | r06 | Customs UnitedCustoms Unite | 5 - 2 | Muangkan UnitedMuangkan Unit |
| 03 Oct 21 | r06 | Udon ThaniUdon Thani | 3 - 2 | Lampang FCLampang FC |
| |
| 09 Oct 21 | r07 | Navy FCNavy FC | 0 - 0 | Kasetsart FCKasetsart FC |
| 09 Oct 21 | r07 | Nakhon Pathom UnitedNakhon Pathom | 1 - 4 | Rayong FCRayong FC |
| 09 Oct 21 | r07 | Chiangmai FCChiangmai FC | 2 - 0 | Ayutthaya FCAyutthaya FC |
| 09 Oct 21 | r07 | Ranong UnitedRanong United | 1 - 1 | Sukhothai FCSukhothai FC |
| 09 Oct 21 | r07 | Lampang FCLampang FC | 1 - 1 | Raj PrachaRaj Pracha |
| 10 Oct 21 | r07 | ChainatChainat | 2 - 1 | KhonkaenKhonkaen |
| 10 Oct 21 | r07 | Muangkan UnitedMuangkan Unit | 0 - 1 | Lamphun WarriorLamphun Warri |
| 10 Oct 21 | r07 | Phrae UnitedPhrae United | 2 - 1 | Customs UnitedCustoms Unite |
| 10 Oct 21 | r07 | Trat FCTrat FC | 2 - 1 | Udon ThaniUdon Thani |
| |
| 13 Oct 21 | r08 | Customs UnitedCustoms Unite | 1 - 2 | Lampang FCLampang FC |
| 13 Oct 21 | r08 | Kasetsart FCKasetsart FC | 0 - 1 | Phrae UnitedPhrae United |
| 13 Oct 21 | r08 | Rayong FCRayong FC | 0 - 1 | Trat FCTrat FC |
| 13 Oct 21 | r08 | Lamphun WarriorLamphun Warri | 3 - 0 | ChainatChainat |
| 13 Oct 21 | r08 | Ranong UnitedRanong United | 1 - 1 | Chiangmai FCChiangmai FC |
| 13 Oct 21 | r08 | Ayutthaya FCAyutthaya FC | 4 - 0 | Navy FCNavy FC |
| 13 Oct 21 | r08 | KhonkaenKhonkaen | 1 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 13 Oct 21 | r08 | Udon ThaniUdon Thani | 1 - 0 | Raj PrachaRaj Pracha |
| 13 Oct 21 | r08 | Sukhothai FCSukhothai FC | 2 - 2 | Muangkan UnitedMuangkan Unit |
| |
| 16 Oct 21 | r09 | Phrae UnitedPhrae United | 1 - 2 | Sukhothai FCSukhothai FC |
| 16 Oct 21 | r09 | Phrae UnitedPhrae United | 1 - 2 | Sukhothai FCSukhothai FC |
| 16 Oct 21 | r09 | Trat FCTrat FC | 1 - 0 | Kasetsart FCKasetsart FC |
| 16 Oct 21 | r09 | Trat FCTrat FC | 1 - 0 | Kasetsart FCKasetsart FC |
| 16 Oct 21 | r09 | Muangkan UnitedMuangkan Unit | 3 - 3 | KhonkaenKhonkaen |
| 16 Oct 21 | r09 | Lampang FCLampang FC | 3 - 0 | Ayutthaya FCAyutthaya FC |
| 16 Oct 21 | r09 | Raj PrachaRaj Pracha | 3 - 3 | Rayong FCRayong FC |
| 17 Oct 21 | r09 | Navy FCNavy FC | 0 - 1 | Udon ThaniUdon Thani |
| 17 Oct 21 | r09 | Navy FCNavy FC | 0 - 1 | Udon ThaniUdon Thani |
| 17 Oct 21 | r09 | Chiangmai FCChiangmai FC | 1 - 4 | Lamphun WarriorLamphun Warri |
| 17 Oct 21 | r09 | Nakhon Pathom UnitedNakhon Pathom | 4 - 4 | Customs UnitedCustoms Unite |
| 17 Oct 21 | r09 | ChainatChainat | 3 - 1 | Ranong UnitedRanong United |
| 17 Oct 21 | r09 | Chiangmai FCChiangmai FC | 1 - 4 | Lamphun WarriorLamphun Warri |
| |
| 23 Oct 21 | r10 | KhonkaenKhonkaen | 1 - 3 | Lampang FCLampang FC |
| |
| 23 Oct 21 | r26 | Muangkan UnitedMuangkan Unit | 2 - 2 | Ranong UnitedRanong United |
| |
| 23 Oct 21 | r10 | Kasetsart FCKasetsart FC | 1 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 23 Oct 21 | r10 | Sukhothai FCSukhothai FC | 3 - 0 | Navy FCNavy FC |
| 23 Oct 21 | r10 | Customs UnitedCustoms Unite | 1 - 2 | Trat FCTrat FC |
| 24 Oct 21 | r10 | Ayutthaya FCAyutthaya FC | 2 - 0 | Raj PrachaRaj Pracha |
| 24 Oct 21 | r10 | Chiangmai FCChiangmai FC | 1 - 3 | ChainatChainat |
| 24 Oct 21 | r10 | Udon ThaniUdon Thani | 0 - 2 | Rayong FCRayong FC |
| 24 Oct 21 | r10 | Lamphun WarriorLamphun Warri | 1 - 1 | Phrae UnitedPhrae United |
| |
| 30 Oct 21 | r11 | Raj PrachaRaj Pracha | 1 - 1 | Kasetsart FCKasetsart FC |
| 30 Oct 21 | r11 | Rayong FCRayong FC | 3 - 1 | KhonkaenKhonkaen |
| 30 Oct 21 | r11 | Udon ThaniUdon Thani | 1 - 0 | Ayutthaya FCAyutthaya FC |
| 30 Oct 21 | r11 | Trat FCTrat FC | 1 - 0 | ChainatChainat |
| 31 Oct 21 | r11 | Navy FCNavy FC | 3 - 0 | Customs UnitedCustoms Unite |
| 31 Oct 21 | r11 | Nakhon Pathom UnitedNakhon Pathom | 0 - 0 | Lamphun WarriorLamphun Warri |
| 31 Oct 21 | r11 | Lampang FCLampang FC | 1 - 1 | Sukhothai FCSukhothai FC |
| 31 Oct 21 | r11 | Phrae UnitedPhrae United | 1 - 2 | Ranong UnitedRanong United |
| |
| 06 Nov 21 | r12 | Kasetsart FCKasetsart FC | 2 - 2 | Udon ThaniUdon Thani |
| 06 Nov 21 | r12 | Ayutthaya FCAyutthaya FC | 1 - 0 | Rayong FCRayong FC |
| 06 Nov 21 | r12 | Customs UnitedCustoms Unite | 3 - 1 | Raj PrachaRaj Pracha |
| 06 Nov 21 | r12 | ChainatChainat | 0 - 2 | Muangkan UnitedMuangkan Unit |
| 07 Nov 21 | r12 | KhonkaenKhonkaen | 1 - 1 | Trat FCTrat FC |
| 07 Nov 21 | r12 | Ranong UnitedRanong United | 2 - 0 | Navy FCNavy FC |
| 07 Nov 21 | r12 | Sukhothai FCSukhothai FC | 2 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 07 Nov 21 | r12 | Lamphun WarriorLamphun Warri | 3 - 3 | Lampang FCLampang FC |
| |
| 13 Nov 21 | r13 | Nakhon Pathom UnitedNakhon Pathom | 0 - 1 | ChainatChainat |
| 13 Nov 21 | r13 | Ayutthaya FCAyutthaya FC | 1 - 1 | Customs UnitedCustoms Unite |
| 13 Nov 21 | r13 | Navy FCNavy FC | 1 - 1 | Lamphun WarriorLamphun Warri |
| 13 Nov 21 | r13 | Udon ThaniUdon Thani | 4 - 1 | Sukhothai FCSukhothai FC |
| 13 Nov 21 | r13 | Trat FCTrat FC | 1 - 0 | Ranong UnitedRanong United |
| 14 Nov 21 | r13 | Rayong FCRayong FC | 1 - 2 | Kasetsart FCKasetsart FC |
| 14 Nov 21 | r13 | Raj PrachaRaj Pracha | 2 - 0 | KhonkaenKhonkaen |
| 14 Nov 21 | r13 | Lampang FCLampang FC | 1 - 0 | Chiangmai FCChiangmai FC |
| 14 Nov 21 | r13 | Phrae UnitedPhrae United | 2 - 2 | Muangkan UnitedMuangkan Unit |
| |
| 17 Nov 21 | r14 | Kasetsart FCKasetsart FC | 0 - 2 | Ayutthaya FCAyutthaya FC |
| 17 Nov 21 | r14 | KhonkaenKhonkaen | 3 - 1 | Navy FCNavy FC |
| 17 Nov 21 | r14 | Customs UnitedCustoms Unite | 3 - 9 | Udon ThaniUdon Thani |
| 17 Nov 21 | r14 | Lamphun WarriorLamphun Warri | 2 - 0 | Rayong FCRayong FC |
| 17 Nov 21 | r14 | Sukhothai FCSukhothai FC | 4 - 2 | Raj PrachaRaj Pracha |
| 17 Nov 21 | r14 | Ranong UnitedRanong United | 2 - 2 | Lampang FCLampang FC |
| 17 Nov 21 | r14 | ChainatChainat | 2 - 0 | Phrae UnitedPhrae United |
| |
| 17 Nov 21 | r30 | Trat FCTrat FC | 3 - 1 | Chiangmai FCChiangmai FC |
| |
| 17 Nov 21 | r14 | Muangkan UnitedMuangkan Unit | 1 - 2 | Nakhon Pathom UnitedNakhon Pathom |
| |
| 20 Nov 21 | r15  | Raj PrachaRaj Pracha | 1 - 4 | Muangkan UnitedMuangkan Unit |
| 20 Nov 21 | r15 | Nakhon Pathom UnitedNakhon Pathom | 1 - 2 | Ranong UnitedRanong United |
| 20 Nov 21 | r15 | Ayutthaya FCAyutthaya FC | 1 - 1 | Lamphun WarriorLamphun Warri |
| 20 Nov 21 | r15 | Trat FCTrat FC | 1 - 1 | Phrae UnitedPhrae United |
| 20 Nov 21 | r15 | Udon ThaniUdon Thani | 4 - 1 | KhonkaenKhonkaen |
| 21 Nov 21 | r15 | Navy FCNavy FC | 1 - 3 | Chiangmai FCChiangmai FC |
| 21 Nov 21 | r15 | Kasetsart FCKasetsart FC | 1 - 1 | Customs UnitedCustoms Unite |
| 21 Nov 21 | r15 | Rayong FCRayong FC | 1 - 2 | Sukhothai FCSukhothai FC |
| 21 Nov 21 | r15 | Lampang FCLampang FC | 0 - 0 | ChainatChainat |
| |
| 27 Nov 21 | r16 | Customs UnitedCustoms Unite | 1 - 2 | Rayong FCRayong FC |
| 27 Nov 21 | r16 | Ranong UnitedRanong United | 1 - 1 | Raj PrachaRaj Pracha |
| 27 Nov 21 | r16 | Muangkan UnitedMuangkan Unit | 2 - 2 | Trat FCTrat FC |
| 27 Nov 21 | r16 | ChainatChainat | 2 - 0 | Navy FCNavy FC |
| 27 Nov 21 | r16 | Lamphun WarriorLamphun Warri | 2 - 0 | Udon ThaniUdon Thani |
| 28 Nov 21 | r16 | Phrae UnitedPhrae United | 1 - 1 | Lampang FCLampang FC |
| 28 Nov 21 | r16 | KhonkaenKhonkaen | 0 - 0 | Ayutthaya FCAyutthaya FC |
| 28 Nov 21 | r16 | Chiangmai FCChiangmai FC | 1 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 28 Nov 21 | r16 | Sukhothai FCSukhothai FC | 2 - 2 | Kasetsart FCKasetsart FC |
| |
| 01 Dec 21 | r11 | Muangkan UnitedMuangkan Unit | 2 - 1 | Chiangmai FCChiangmai FC |
| |
| 04 Dec 21 | r17 | Raj PrachaRaj Pracha | 0 - 1 | Lamphun WarriorLamphun Warri |
| 04 Dec 21 | r17 | Rayong FCRayong FC | 1 - 1 | ChainatChainat |
| 04 Dec 21 | r17 | Nakhon Pathom UnitedNakhon Pathom | 2 - 1 | Phrae UnitedPhrae United |
| 04 Dec 21 | r17 | Lampang FCLampang FC | 1 - 2 | Trat FCTrat FC |
| 04 Dec 21 | r17 | Navy FCNavy FC | 1 - 2 | Muangkan UnitedMuangkan Unit |
| 05 Dec 21 | r17 | Kasetsart FCKasetsart FC | 2 - 1 | KhonkaenKhonkaen |
| 05 Dec 21 | r17 | Ayutthaya FCAyutthaya FC | 1 - 0 | Ranong UnitedRanong United |
| 05 Dec 21 | r17 | Udon ThaniUdon Thani | 3 - 1 | Chiangmai FCChiangmai FC |
| 05 Dec 21 | r17 | Customs UnitedCustoms Unite | 1 - 4 | Sukhothai FCSukhothai FC |
| |
| 08 Dec 21 | r12 | Chiangmai FCChiangmai FC | 1 - 0 | Phrae UnitedPhrae United |
| |
| 08 Dec 21 | r05 | Lampang FCLampang FC | 2 - 1 | Rayong FCRayong FC |
| |
| 08 Jan 22 | r18 | ChainatChainat | 3 - 2 | Ayutthaya FCAyutthaya FC |
| 08 Jan 22 | r18 | Lamphun WarriorLamphun Warri | 2 - 0 | Customs UnitedCustoms Unite |
| 08 Jan 22 | r18 | Trat FCTrat FC | 2 - 0 | Navy FCNavy FC |
| 08 Jan 22 | r18 | Lampang FCLampang FC | 1 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 08 Jan 22 | r18 | Ranong UnitedRanong United | 0 - 0 | Kasetsart FCKasetsart FC |
| 09 Jan 22 | r18 | KhonkaenKhonkaen | 1 - 2 | Sukhothai FCSukhothai FC |
| 09 Jan 22 | r18 | Muangkan UnitedMuangkan Unit | 3 - 1 | Rayong FCRayong FC |
| 09 Jan 22 | r18 | Chiangmai FCChiangmai FC | 0 - 0 | Raj PrachaRaj Pracha |
| |
| 15 Jan 22 | r19 | Ayutthaya FCAyutthaya FC | 1 - 3 | Muangkan UnitedMuangkan Unit |
| 15 Jan 22 | r19 | Sukhothai FCSukhothai FC | 2 - 2 | Trat FCTrat FC |
| |
| 15 Jan 22 | r03 | Chiangmai FCChiangmai FC | 2 - 0 | Kasetsart FCKasetsart FC |
| |
| 15 Jan 22 | r19 | Customs UnitedCustoms Unite | 2 - 0 | Ranong UnitedRanong United |
| 16 Jan 22 | r19 | Rayong FCRayong FC | 3 - 2 | Phrae UnitedPhrae United |
| 16 Jan 22 | r19 | KhonkaenKhonkaen | 0 - 1 | Lamphun WarriorLamphun Warri |
| |
| 16 Jan 22 | r03 | Lampang FCLampang FC | 2 - 2 | Navy FCNavy FC |
| |
| 16 Jan 22 | r19 | Raj PrachaRaj Pracha | 2 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| |
| 22 Jan 22 | r20 | Trat FCTrat FC | 1 - 0 | Raj PrachaRaj Pracha |
| 22 Jan 22 | r20 | Lamphun WarriorLamphun Warri | 1 - 1 | Sukhothai FCSukhothai FC |
| 22 Jan 22 | r20 | Lampang FCLampang FC | 5 - 1 | Kasetsart FCKasetsart FC |
| 22 Jan 22 | r20 | Nakhon Pathom UnitedNakhon Pathom | 3 - 2 | Navy FCNavy FC |
| 22 Jan 22 | r20 | Phrae UnitedPhrae United | 2 - 2 | Ayutthaya FCAyutthaya FC |
| 22 Jan 22 | r20 | Ayutthaya FCAyutthaya FC | 2 - 2 | Phrae UnitedPhrae United |
| 23 Jan 22 | r20 | ChainatChainat | 2 - 2 | Customs UnitedCustoms Unite |
| 23 Jan 22 | r20 | Ranong UnitedRanong United | 1 - 0 | Rayong FCRayong FC |
| 23 Jan 22 | r20 | Chiangmai FCChiangmai FC | 2 - 1 | KhonkaenKhonkaen |
| 23 Jan 22 | r20 | Muangkan UnitedMuangkan Unit | 6 - 1 | Udon ThaniUdon Thani |
| |
| 26 Jan 22 | r18 | Phrae UnitedPhrae United | 2 - 1 | Udon ThaniUdon Thani |
| |
| 29 Jan 22 | r21 | Sukhothai FCSukhothai FC | 3 - 0 | ChainatChainat |
| 29 Jan 22 | r21 | Udon ThaniUdon Thani | 0 - 4 | Nakhon Pathom UnitedNakhon Pathom |
| 29 Jan 22 | r21 | KhonkaenKhonkaen | 1 - 1 | Phrae UnitedPhrae United |
| 29 Jan 22 | r21 | Kasetsart FCKasetsart FC | 2 - 2 | Muangkan UnitedMuangkan Unit |
| 29 Jan 22 | r21 | Customs UnitedCustoms Unite | 0 - 0 | Chiangmai FCChiangmai FC |
| 30 Jan 22 | r21 | Raj PrachaRaj Pracha | 1 - 0 | Navy FCNavy FC |
| 30 Jan 22 | r21 | Lamphun WarriorLamphun Warri | 4 - 1 | Ranong UnitedRanong United |
| 30 Jan 22 | r21 | Ayutthaya FCAyutthaya FC | 0 - 0 | Trat FCTrat FC |
| 30 Jan 22 | r21 | Rayong FCRayong FC | 3 - 1 | Lampang FCLampang FC |
| |
| 02 Feb 22 | r19 | Udon ThaniUdon Thani | 1 - 1 | ChainatChainat |
| |
| 04 Feb 22 | r22 | Chiangmai FCChiangmai FC | 1 - 2 | Sukhothai FCSukhothai FC |
| 05 Feb 22 | r22 | Ranong UnitedRanong United | 2 - 1 | KhonkaenKhonkaen |
| 05 Feb 22 | r22 | Navy FCNavy FC | 1 - 0 | Rayong FCRayong FC |
| 05 Feb 22 | r22 | Rayong FCRayong FC | 1 - 0 | Navy FCNavy FC |
| 05 Feb 22 | r22 | Phrae UnitedPhrae United | 1 - 1 | Raj PrachaRaj Pracha |
| 05 Feb 22 | r22 | Trat FCTrat FC | 0 - 1 | Lamphun WarriorLamphun Warri |
| 06 Feb 22 | r22 | ChainatChainat | 3 - 2 | Kasetsart FCKasetsart FC |
| 06 Feb 22 | r22 | Nakhon Pathom UnitedNakhon Pathom | 0 - 0 | Ayutthaya FCAyutthaya FC |
| 06 Feb 22 | r22 | Lampang FCLampang FC | 2 - 0 | Udon ThaniUdon Thani |
| 06 Feb 22 | r22 | Muangkan UnitedMuangkan Unit | 1 - 0 | Customs UnitedCustoms Unite |
| |
| 11 Feb 22 | r23 | Customs UnitedCustoms Unite | 1 - 3 | Phrae UnitedPhrae United |
| 12 Feb 22 | r23 | Udon ThaniUdon Thani | 1 - 2 | Trat FCTrat FC |
| 12 Feb 22 | r23 | KhonkaenKhonkaen | 1 - 1 | ChainatChainat |
| 12 Feb 22 | r23 | Rayong FCRayong FC | 0 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 12 Feb 22 | r23 | Lamphun WarriorLamphun Warri | 3 - 1 | Muangkan UnitedMuangkan Unit |
| 13 Feb 22 | r23 | Kasetsart FCKasetsart FC | 1 - 0 | Navy FCNavy FC |
| 13 Feb 22 | r23 | Ayutthaya FCAyutthaya FC | 2 - 1 | Chiangmai FCChiangmai FC |
| 13 Feb 22 | r23 | Sukhothai FCSukhothai FC | 5 - 1 | Ranong UnitedRanong United |
| 13 Feb 22 | r23 | Raj PrachaRaj Pracha | 0 - 2 | Lampang FCLampang FC |
| |
| 18 Feb 22 | r24 | Muangkan UnitedMuangkan Unit | 3 - 1 | Sukhothai FCSukhothai FC |
| 19 Feb 22 | r24 | Trat FCTrat FC | 1 - 1 | Rayong FCRayong FC |
| 19 Feb 22 | r24 | Lampang FCLampang FC | 2 - 0 | Customs UnitedCustoms Unite |
| 19 Feb 22 | r24 | Phrae UnitedPhrae United | 0 - 0 | Kasetsart FCKasetsart FC |
| 19 Feb 22 | r24 | Nakhon Pathom UnitedNakhon Pathom | 1 - 0 | KhonkaenKhonkaen |
| 20 Feb 22 | r24 | Raj PrachaRaj Pracha | 0 - 1 | Udon ThaniUdon Thani |
| 20 Feb 22 | r24 | ChainatChainat | 3 - 3 | Lamphun WarriorLamphun Warri |
| 20 Feb 22 | r24 | Navy FCNavy FC | 3 - 4 | Ayutthaya FCAyutthaya FC |
| 20 Feb 22 | r24 | Chiangmai FCChiangmai FC | 0 - 0 | Ranong UnitedRanong United |
| |
| 25 Feb 22 | r25 | Lamphun WarriorLamphun Warri | 3 - 2 | Chiangmai FCChiangmai FC |
| 26 Feb 22 | r25 | Rayong FCRayong FC | 1 - 0 | Raj PrachaRaj Pracha |
| 26 Feb 22 | r25 | Ayutthaya FCAyutthaya FC | 1 - 1 | Lampang FCLampang FC |
| 26 Feb 22 | r25 | Sukhothai FCSukhothai FC | 0 - 3 | Phrae UnitedPhrae United |
| 26 Feb 22 | r25 | KhonkaenKhonkaen | 2 - 2 | Muangkan UnitedMuangkan Unit |
| 27 Feb 22 | r25 | Customs UnitedCustoms Unite | 0 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 27 Feb 22 | r25 | Udon ThaniUdon Thani | 1 - 0 | Navy FCNavy FC |
| 27 Feb 22 | r25 | Kasetsart FCKasetsart FC | 2 - 0 | Trat FCTrat FC |
| 27 Feb 22 | r25 | Ranong UnitedRanong United | 0 - 1 | ChainatChainat |
| |
| 04 Mar 22 | r10 | Ranong UnitedRanong United | 1 - 2 | Muangkan UnitedMuangkan Unit |
| |
| 05 Mar 22 | r26 | Lampang FCLampang FC | 7 - 1 | KhonkaenKhonkaen |
| 05 Mar 22 | r26 | Phrae UnitedPhrae United | 3 - 2 | Lamphun WarriorLamphun Warri |
| 05 Mar 22 | r26 | Trat FCTrat FC | 2 - 1 | Customs UnitedCustoms Unite |
| 05 Mar 22 | r26 | ChainatChainat | 2 - 2 | Chiangmai FCChiangmai FC |
| 06 Mar 22 | r26 | Nakhon Pathom UnitedNakhon Pathom | 1 - 0 | Kasetsart FCKasetsart FC |
| 06 Mar 22 | r26 | Raj PrachaRaj Pracha | 3 - 0 | Ayutthaya FCAyutthaya FC |
| 06 Mar 22 | r26 | Navy FCNavy FC | 1 - 2 | Sukhothai FCSukhothai FC |
| 06 Mar 22 | r26 | Rayong FCRayong FC | 3 - 0 | Udon ThaniUdon Thani |
| |
| 11 Mar 22 | r27 | KhonkaenKhonkaen | 0 - 0 | Rayong FCRayong FC |
| 12 Mar 22 | r27 | Chiangmai FCChiangmai FC | 1 - 3 | Muangkan UnitedMuangkan Unit |
| 12 Mar 22 | r27 | Ranong UnitedRanong United | 1 - 0 | Phrae UnitedPhrae United |
| 12 Mar 22 | r27 | Ayutthaya FCAyutthaya FC | 1 - 1 | Udon ThaniUdon Thani |
| 12 Mar 22 | r27 | Sukhothai FCSukhothai FC | 2 - 1 | Lampang FCLampang FC |
| 13 Mar 22 | r27 | Customs UnitedCustoms Unite | 2 - 1 | Navy FCNavy FC |
| 13 Mar 22 | r27 | ChainatChainat | 2 - 0 | Trat FCTrat FC |
| 13 Mar 22 | r27 | Lamphun WarriorLamphun Warri | 3 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 13 Mar 22 | r27 | Kasetsart FCKasetsart FC | 3 - 2 | Raj PrachaRaj Pracha |
| |
| 18 Mar 22 | r28 | Udon ThaniUdon Thani | 1 - 2 | Kasetsart FCKasetsart FC |
| 19 Mar 22 | r28 | Rayong FCRayong FC | 0 - 1 | Ayutthaya FCAyutthaya FC |
| 19 Mar 22 | r28 | Phrae UnitedPhrae United | 3 - 0 | Chiangmai FCChiangmai FC |
| 19 Mar 22 | r28 | Nakhon Pathom UnitedNakhon Pathom | 1 - 0 | Sukhothai FCSukhothai FC |
| 19 Mar 22 | r28 | Muangkan UnitedMuangkan Unit | 0 - 1 | ChainatChainat |
| 20 Mar 22 | r28 | Trat FCTrat FC | 2 - 3 | KhonkaenKhonkaen |
| 20 Mar 22 | r28 | Raj PrachaRaj Pracha | 3 - 0 | Customs UnitedCustoms Unite |
| 20 Mar 22 | r28 | Lampang FCLampang FC | 0 - 1 | Lamphun WarriorLamphun Warri |
| 20 Mar 22 | r28 | Navy FCNavy FC | 1 - 1 | Ranong UnitedRanong United |
| |
| 25 Mar 22 | r29 | ChainatChainat | 3 - 0 | Nakhon Pathom UnitedNakhon Pathom |
| 26 Mar 22 | r29 | Lamphun WarriorLamphun Warri | 4 - 0 | Navy FCNavy FC |
| 26 Mar 22 | r29 | Customs UnitedCustoms Unite | 1 - 0 | Ayutthaya FCAyutthaya FC |
| 26 Mar 22 | r29 | Muangkan UnitedMuangkan Unit | 2 - 1 | Phrae UnitedPhrae United |
| 26 Mar 22 | r29 | Chiangmai FCChiangmai FC | 0 - 6 | Lampang FCLampang FC |
| 27 Mar 22 | r29 | Sukhothai FCSukhothai FC | 5 - 0 | Udon ThaniUdon Thani |
| 27 Mar 22 | r29 | KhonkaenKhonkaen | 1 - 0 | Raj PrachaRaj Pracha |
| 27 Mar 22 | r29 | Kasetsart FCKasetsart FC | 1 - 1 | Rayong FCRayong FC |
| 27 Mar 22 | r29 | Ranong UnitedRanong United | 1 - 0 | Trat FCTrat FC |
| |
| 01 Apr 22 | r30 | Navy FCNavy FC | 3 - 0 | KhonkaenKhonkaen |
| 02 Apr 22 | r30 | Lampang FCLampang FC | 2 - 0 | Ranong UnitedRanong United |
| 02 Apr 22 | r30 | Phrae UnitedPhrae United | 2 - 2 | ChainatChainat |
| 02 Apr 22 | r30 | Udon ThaniUdon Thani | 1 - 1 | Customs UnitedCustoms Unite |
| 02 Apr 22 | r30 | Rayong FCRayong FC | 0 - 1 | Lamphun WarriorLamphun Warri |
| 03 Apr 22 | r30 | Raj PrachaRaj Pracha | 0 - 1 | Sukhothai FCSukhothai FC |
| 03 Apr 22 | r30 | Nakhon Pathom UnitedNakhon Pathom | 4 - 4 | Muangkan UnitedMuangkan Unit |
| |
| 03 Apr 22 | r14 | Chiangmai FCChiangmai FC | 0 - 1 | Trat FCTrat FC |
| |
| 03 Apr 22 | r30 | Ayutthaya FCAyutthaya FC | 1 - 1 | Kasetsart FCKasetsart FC |
| |
| 08 Apr 22 | r31 | Sukhothai FCSukhothai FC | 2 - 1 | Rayong FCRayong FC |
| 09 Apr 22 | r31 | Ranong UnitedRanong United | 0 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 09 Apr 22 | r31 | Phrae UnitedPhrae United | 2 - 0 | Trat FCTrat FC |
| 09 Apr 22 | r31 | Chiangmai FCChiangmai FC | 2 - 1 | Navy FCNavy FC |
| 09 Apr 22 | r31 | Lamphun WarriorLamphun Warri | 2 - 1 | Ayutthaya FCAyutthaya FC |
| 10 Apr 22 | r31 | ChainatChainat | 1 - 1 | Lampang FCLampang FC |
| 10 Apr 22 | r31 | Muangkan UnitedMuangkan Unit | 2 - 2 | Raj PrachaRaj Pracha |
| 10 Apr 22 | r31 | Customs UnitedCustoms Unite | 2 - 1 | Kasetsart FCKasetsart FC |
| 10 Apr 22 | r31 | KhonkaenKhonkaen | 1 - 3 | Udon ThaniUdon Thani |
| |
| 15 Apr 22 | r32 | Raj PrachaRaj Pracha | 1 - 0 | Ranong UnitedRanong United |
| 16 Apr 22 | r32 | Ayutthaya FCAyutthaya FC | 1 - 0 | KhonkaenKhonkaen |
| 16 Apr 22 | r32 | Navy FCNavy FC | 1 - 3 | ChainatChainat |
| 16 Apr 22 | r32 | Nakhon Pathom UnitedNakhon Pathom | 1 - 2 | Chiangmai FCChiangmai FC |
| 16 Apr 22 | r32 | Trat FCTrat FC | 4 - 1 | Muangkan UnitedMuangkan Unit |
| 17 Apr 22 | r32 | Lampang FCLampang FC | 0 - 1 | Phrae UnitedPhrae United |
| 17 Apr 22 | r32 | Udon ThaniUdon Thani | 1 - 3 | Lamphun WarriorLamphun Warri |
| 17 Apr 22 | r32 | Kasetsart FCKasetsart FC | 1 - 4 | Sukhothai FCSukhothai FC |
| 17 Apr 22 | r32 | Rayong FCRayong FC | 2 - 0 | Customs UnitedCustoms Unite |
| |
| 23 Apr 22 | r33 | Phrae UnitedPhrae United | 1 - 1 | Nakhon Pathom UnitedNakhon Pathom |
| 23 Apr 22 | r33 | Chiangmai FCChiangmai FC | 1 - 1 | Udon ThaniUdon Thani |
| 23 Apr 22 | r33 | Trat FCTrat FC | 4 - 2 | Lampang FCLampang FC |
| 23 Apr 22 | r33 | KhonkaenKhonkaen | 0 - 0 | Kasetsart FCKasetsart FC |
| 23 Apr 22 | r33 | Muangkan UnitedMuangkan Unit | 3 - 2 | Navy FCNavy FC |
| 24 Apr 22 | r33 | Sukhothai FCSukhothai FC | 1 - 0 | Customs UnitedCustoms Unite |
| 24 Apr 22 | r33 | ChainatChainat | 2 - 2 | Rayong FCRayong FC |
| 24 Apr 22 | r33 | Lamphun WarriorLamphun Warri | 2 - 0 | Raj PrachaRaj Pracha |
| 24 Apr 22 | r33 | Ranong UnitedRanong United | 1 - 1 | Ayutthaya FCAyutthaya FC |
| |
| 30 Apr 22 | r34 | Muangkan UnitedMuangkan Unit | 1 - 3 | Lampang FCLampang FC |
| 30 Apr 22 | r34 | Navy FCNavy FC | 1 - 3 | Phrae UnitedPhrae United |
| 30 Apr 22 | r34 | Ayutthaya FCAyutthaya FC | 1 - 2 | Sukhothai FCSukhothai FC |
| 30 Apr 22 | r34 | Customs UnitedCustoms Unite | 1 - 0 | KhonkaenKhonkaen |
| 30 Apr 22 | r34 | Nakhon Pathom UnitedNakhon Pathom | 1 - 1 | Trat FCTrat FC |
| 30 Apr 22 | r34 | Raj PrachaRaj Pracha | 4 - 1 | ChainatChainat |
| 30 Apr 22 | r34 | Lampang FCLampang FC | 1 - 3 | Muangkan UnitedMuangkan Unit |
| 30 Apr 22 | r34 | Udon ThaniUdon Thani | 0 - 1 | Ranong UnitedRanong United |
| 30 Apr 22 | r34 | Kasetsart FCKasetsart FC | 0 - 3 | Lamphun WarriorLamphun Warri |
| 30 Apr 22 | r34 | Rayong FCRayong FC | 3 - 2 | Chiangmai FCChiangmai FC |
| |
| 08 May 22 | r00 | Phrae UnitedPhrae United | 1 - 1 | Trat FCTrat FC |
| 08 May 22 | r00 | ChainatChainat | 1 - 2 | Lampang FCLampang FC |
| 14 May 22 | r00 | Lampang FCLampang FC | 2 - 0 | ChainatChainat |
| 14 May 22 | r00 | Trat FCTrat FC | 1 - 0 | Phrae UnitedPhrae United |
| 21 May 22 | r00 | Lampang FCLampang FC | 2 - 2 | Trat FCTrat FC |
| 28 May 22 | r00 | Trat FCTrat FC | 3 - 3 | Lampang FCLampang FC |
Team 2021-2022 Schedules
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