| 13 Mar 21 | r00  | Richmond F.C.Richmond F.C. | 7 - 27 | Cornish PiratesCornish Pirat |
| 21 Mar 21 | r00 | Cornish PiratesCornish Pirat | 27 - 12 | Bedford BluesBedford Blues |
| 27 Mar 21 | r00 | Doncaster KnightsDoncaster Kni | 17 - 15 | Cornish PiratesCornish Pirat |
| 10 Apr 21 | r00 | Cornish PiratesCornish Pirat | 10 - 38 | Ealing TrailfindersEaling Trailf |
| 17 Apr 21 | r00 | Nottingham R.F.C.Nottingham R. | 22 - 33 | Cornish PiratesCornish Pirat |
| 24 Apr 21 | r00 | Cornish PiratesCornish Pirat | 18 - 20 | Ampthill RUFCAmpthill RUFC |
| 01 May 21 | r00 | Coventry R.F.C.Coventry R.F. | 19 - 30 | Cornish PiratesCornish Pirat |
| 15 May 21 | r00 | Cornish PiratesCornish Pirat | 52 - 26 | Hartpury University R.F.CHartpury Univ |
| 29 May 21 | r00 | Jersey RedsJersey Reds | 32 - 31 | Cornish PiratesCornish Pirat |
| 18 Sep 21 | r00 | Cornish PiratesCornish Pirat | 33 - 18 | Richmond F.C.Richmond F.C. |
| 25 Sep 21 | r00 | Hartpury University R.F.CHartpury Univ | 37 - 18 | Cornish PiratesCornish Pirat |
| 03 Oct 21 | r00 | Cornish PiratesCornish Pirat | 15 - 12 | Ealing TrailfindersEaling Trailf |
| 22 Oct 21 | r00 | Nottingham R.F.C.Nottingham R. | 8 - 32 | Cornish PiratesCornish Pirat |
| 30 Oct 21 | r00 | Cornish PiratesCornish Pirat | 40 - 5 | Coventry R.F.C.Coventry R.F. |
| 06 Nov 21 | r00 | London ScottishLondon Scotti | 17 - 19 | Cornish PiratesCornish Pirat |
| 20 Nov 21 | r00 | Cornish PiratesCornish Pirat | 39 - 24 | Bedford BluesBedford Blues |
| 27 Nov 21 | r00 | Jersey RedsJersey Reds | 15 - 5 | Cornish PiratesCornish Pirat |
| 05 Dec 21 | r00 | Cornish PiratesCornish Pirat | 29 - 7 | Doncaster KnightsDoncaster Kni |
| 11 Dec 21 | r00 | Ampthill RUFCAmpthill RUFC | 13 - 26 | Cornish PiratesCornish Pirat |
| 22 Jan 22 | r00 | Cornish PiratesCornish Pirat | 52 - 17 | Nottingham R.F.C.Nottingham R. |
| 29 Jan 22 | r00 | Coventry R.F.C.Coventry R.F. | 21 - 31 | Cornish PiratesCornish Pirat |
| 05 Feb 22 | r00 | Richmond F.C.Richmond F.C. | 24 - 24 | Cornish PiratesCornish Pirat |
| 12 Feb 22 | r00 | Cornish PiratesCornish Pirat | 19 - 0 | London ScottishLondon Scotti |
| 19 Feb 22 | r00 | Bedford BluesBedford Blues | 12 - 20 | Cornish PiratesCornish Pirat |
| 27 Feb 22 | r00 | Cornish PiratesCornish Pirat | 21 - 17 | Jersey RedsJersey Reds |
| 12 Mar 22 | r00 | Doncaster KnightsDoncaster Kni | 22 - 15 | Cornish PiratesCornish Pirat |
| 19 Mar 22 | r00 | Cornish PiratesCornish Pirat | 31 - 24 | Hartpury University R.F.CHartpury Univ |
| 26 Mar 22 | r00 | Ealing TrailfindersEaling Trailf | 44 - 24 | Cornish PiratesCornish Pirat |
| 02 Apr 22 | r00 | Cornish PiratesCornish Pirat | 28 - 28 | Ampthill RUFCAmpthill RUFC |
Team 2021-2022 Schedules
Ampthill RUFC
Bedford Blues
Caldy Rugby Football Club
Cambridge RUFC
Chinnor RFC
Cornish Pirates
Coventry R.F.C.
Doncaster Knights
Ealing Trailfinders
Hartpury University R.F.C.
London Scottish
Nottingham R.F.C.
Richmond F.C.
Worcester Warriors
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