| 16 Jul 21 | r01   | CFR Cluj-NapocaCFR Cluj-Napo | 3 - 2 | FC U Craiova 1948FC U Craiova |
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| 24 Jul 21 | r02 | Academica ClinceniAcademica Cli | 1 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 31 Jul 21 | r03 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Chindia TârgovișteChindia Târgo |
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| 06 Aug 21 | r04 | CS MioveniCS Mioveni | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 13 Aug 21 | r05  | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Farul ConstantaFarul Constan |
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| 21 Aug 21 | r06 | Arges PitestiArges Pitesti | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 29 Aug 21 | r07 | CFR Cluj-NapocaCFR Cluj-Napo | 4 - 1 | Steaua BucurestiSteaua Bucure |
| |
| 11 Sep 21 | r08 | FC BotoșaniFC Botoșani | 1 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 20 Sep 21 | r09 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Universitatea CraiovaUniversitatea |
| |
| 26 Sep 21 | r10 | Uta AradUta Arad | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 03 Oct 21 | r11 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Gaz Metan MediașGaz Metan Med |
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| 17 Oct 21 | r12 | Rapid BucurestiRapid Bucures | 2 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 25 Oct 21 | r13 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| |
| 30 Oct 21 | r14 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | FC VoluntariFC Voluntari |
| |
| 07 Nov 21 | r15 | Dinamo Bucuresti Dinamo Bucure | 0 - 3 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 20 Nov 21 | r16 | FC U Craiova 1948FC U Craiova | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 29 Nov 21 | r17 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Academica ClinceniAcademica Cli |
| |
| 04 Dec 21 | r18 | Chindia TârgovișteChindia Târgo | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 12 Dec 21 | r19 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | CS MioveniCS Mioveni |
| |
| 16 Dec 21 | r20 | Farul ConstantaFarul Constan | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 19 Dec 21 | r21 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Arges PitestiArges Pitesti |
| |
| 23 Jan 22 | r22 | Steaua BucurestiSteaua Bucure | 3 - 3 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 31 Jan 22 | r23 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 1 | FC BotoșaniFC Botoșani |
| |
| 05 Feb 22 | r24 | Universitatea CraiovaUniversitatea | 1 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 08 Feb 22 | r25 | CFR Cluj-NapocaCFR Cluj-Napo | 0 - 0 | Uta AradUta Arad |
| |
| 12 Feb 22 | r26 | Gaz Metan MediașGaz Metan Med | 1 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 20 Feb 22 | r27 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Rapid BucurestiRapid Bucures |
| |
| 26 Feb 22 | r28 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 02 Mar 22 | r29 | FC VoluntariFC Voluntari | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 06 Mar 22 | r30 | CFR Cluj-NapocaCFR Cluj-Napo | 4 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 12 Mar 22 | r01 | CFR Cluj-NapocaCFR Cluj-Napo | 3 - 1 | FC VoluntariFC Voluntari |
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| 19 Mar 22 | r02 | Farul ConstantaFarul Constan | 0 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 04 Apr 22 | r03 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Arges PitestiArges Pitesti |
| |
| 10 Apr 22 | r04 | Universitatea CraiovaUniversitatea | 3 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 17 Apr 22 | r05 | CFR Cluj-NapocaCFR Cluj-Napo | 0 - 1 | Steaua BucurestiSteaua Bucure |
| |
| 24 Apr 22 | r06 | FC VoluntariFC Voluntari | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 01 May 22 | r07 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Farul ConstantaFarul Constan |
| |
| 07 May 22 | r08 | Arges PitestiArges Pitesti | 0 - 6 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 15 May 22 | r09 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Universitatea CraiovaUniversitatea |
| |
| 22 May 22 | r10 | Steaua BucurestiSteaua Bucure | 3 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
Team 2021-2022 Schedules
Argeș Pitești
Botoșani
CFR Cluj
Csíkszereda Miercurea Ciuc
Dinamo București
Farul Constanța
FCSB
Hermannstadt
Metaloglobus București
Oțelul Galați
Petrolul Ploiești
Rapid București
Unirea Slobozia
Universitatea Cluj
Universitatea Craiova
UTA Arad
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