| 15 Jul 21 | r01   | FC BotoșaniFC Botoșani | 0 - 0 | Steaua BucurestiSteaua Bucure |
| 16 Jul 21 | r01 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 2 - 0 | Academica ClinceniAcademica Cli |
| 16 Jul 21 | r01 | CFR Cluj-NapocaCFR Cluj-Napo | 3 - 2 | FC U Craiova 1948FC U Craiova |
| 17 Jul 21 | r01 | Gaz Metan MediașGaz Metan Med | 1 - 0 | CS MioveniCS Mioveni |
| 17 Jul 21 | r01 | Universitatea CraiovaUniversitatea | 1 - 0 | Arges PitestiArges Pitesti |
| 18 Jul 21 | r01 | Uta AradUta Arad | 0 - 0 | Farul ConstantaFarul Constan |
| 18 Jul 21 | r01 | Rapid BucurestiRapid Bucures | 1 - 0 | Chindia TârgovișteChindia Târgo |
| 19 Jul 21 | r01 | Dinamo Bucuresti Dinamo Bucure | 3 - 2 | FC VoluntariFC Voluntari |
| |
| 23 Jul 21 | r02 | Arges PitestiArges Pitesti | 0 - 1 | Uta AradUta Arad |
| 23 Jul 21 | r02 | CS MioveniCS Mioveni | 0 - 2 | Rapid BucurestiRapid Bucures |
| 24 Jul 21 | r02 | FC VoluntariFC Voluntari | 0 - 1 | FC BotoșaniFC Botoșani |
| 24 Jul 21 | r02 | Academica ClinceniAcademica Cli | 1 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| 25 Jul 21 | r02 | Farul ConstantaFarul Constan | 2 - 0 | Gaz Metan MediașGaz Metan Med |
| 25 Jul 21 | r02 | Steaua BucurestiSteaua Bucure | 4 - 1 | Universitatea CraiovaUniversitatea |
| 26 Jul 21 | r02 | Chindia TârgovișteChindia Târgo | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 26 Jul 21 | r02 | FC U Craiova 1948FC U Craiova | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
| |
| 30 Jul 21 | r03 | Gaz Metan MediașGaz Metan Med | 2 - 2 | Arges PitestiArges Pitesti |
| 30 Jul 21 | r03 | Rapid BucurestiRapid Bucures | 0 - 0 | Farul ConstantaFarul Constan |
| 31 Jul 21 | r03 | FC VoluntariFC Voluntari | 2 - 1 | FC U Craiova 1948FC U Craiova |
| 31 Jul 21 | r03 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Chindia TârgovișteChindia Târgo |
| 01 Aug 21 | r03 | Universitatea CraiovaUniversitatea | 1 - 2 | FC BotoșaniFC Botoșani |
| 01 Aug 21 | r03 | Uta AradUta Arad | 1 - 1 | Steaua BucurestiSteaua Bucure |
| 02 Aug 21 | r03 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 1 - 2 | CS MioveniCS Mioveni |
| 02 Aug 21 | r03 | Dinamo Bucuresti Dinamo Bucure | 3 - 1 | Academica ClinceniAcademica Cli |
| |
| 06 Aug 21 | r04  | FC BotoșaniFC Botoșani | 2 - 1 | Uta AradUta Arad |
| 06 Aug 21 | r04 | CS MioveniCS Mioveni | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 07 Aug 21 | r04 | Academica ClinceniAcademica Cli | 1 - 2 | FC U Craiova 1948FC U Craiova |
| 07 Aug 21 | r04 | Arges PitestiArges Pitesti | 0 - 1 | Rapid BucurestiRapid Bucures |
| 08 Aug 21 | r04 | Chindia TârgovișteChindia Târgo | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
| 08 Aug 21 | r04 | Steaua BucurestiSteaua Bucure | 2 - 1 | Gaz Metan MediașGaz Metan Med |
| 09 Aug 21 | r04 | Farul ConstantaFarul Constan | 1 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 09 Aug 21 | r04 | Universitatea CraiovaUniversitatea | 3 - 0 | FC VoluntariFC Voluntari |
| |
| 13 Aug 21 | r05 | FC VoluntariFC Voluntari | 1 - 0 | Academica ClinceniAcademica Cli |
| 13 Aug 21 | r05 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Farul ConstantaFarul Constan |
| 14 Aug 21 | r05 | FC U Craiova 1948FC U Craiova | 0 - 0 | Chindia TârgovișteChindia Târgo |
| 14 Aug 21 | r05 | Uta AradUta Arad | 1 - 0 | Universitatea CraiovaUniversitatea |
| 15 Aug 21 | r05 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 2 | Arges PitestiArges Pitesti |
| 15 Aug 21 | r05 | Rapid BucurestiRapid Bucures | 1 - 0 | Steaua BucurestiSteaua Bucure |
| 16 Aug 21 | r05 | Gaz Metan MediașGaz Metan Med | 0 - 1 | FC BotoșaniFC Botoșani |
| 16 Aug 21 | r05 | Dinamo Bucuresti Dinamo Bucure | 0 - 1 | CS MioveniCS Mioveni |
| |
| 20 Aug 21 | r06 | Chindia TârgovișteChindia Târgo | 2 - 2 | Academica ClinceniAcademica Cli |
| 20 Aug 21 | r06 | Farul ConstantaFarul Constan | 3 - 0 | Dinamo Bucuresti Dinamo Bucure |
| 21 Aug 21 | r06 | Universitatea CraiovaUniversitatea | 1 - 0 | Gaz Metan MediașGaz Metan Med |
| 21 Aug 21 | r06 | Arges PitestiArges Pitesti | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 22 Aug 21 | r06 | Uta AradUta Arad | 2 - 0 | FC VoluntariFC Voluntari |
| 22 Aug 21 | r06 | FC BotoșaniFC Botoșani | 0 - 2 | Rapid BucurestiRapid Bucures |
| 23 Aug 21 | r06 | CS MioveniCS Mioveni | 1 - 0 | FC U Craiova 1948FC U Craiova |
| 23 Aug 21 | r06 | Steaua BucurestiSteaua Bucure | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| |
| 27 Aug 21 | r07 | FC VoluntariFC Voluntari | 2 - 1 | Chindia TârgovișteChindia Târgo |
| 27 Aug 21 | r07 | FC U Craiova 1948FC U Craiova | 1 - 1 | Farul ConstantaFarul Constan |
| 28 Aug 21 | r07 | Dinamo Bucuresti Dinamo Bucure | 0 - 2 | Arges PitestiArges Pitesti |
| 28 Aug 21 | r07 | Rapid BucurestiRapid Bucures | 1 - 2 | Universitatea CraiovaUniversitatea |
| 29 Aug 21 | r07 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 1 - 1 | FC BotoșaniFC Botoșani |
| 29 Aug 21 | r07 | CFR Cluj-NapocaCFR Cluj-Napo | 4 - 1 | Steaua BucurestiSteaua Bucure |
| 30 Aug 21 | r07 | Academica ClinceniAcademica Cli | 1 - 1 | CS MioveniCS Mioveni |
| 30 Aug 21 | r07 | Gaz Metan MediașGaz Metan Med | 0 - 1 | Uta AradUta Arad |
| |
| 10 Sep 21 | r08 | CS MioveniCS Mioveni | 0 - 1 | Chindia TârgovișteChindia Târgo |
| 10 Sep 21 | r08 | Uta AradUta Arad | 2 - 2 | Rapid BucurestiRapid Bucures |
| 11 Sep 21 | r08 | Arges PitestiArges Pitesti | 1 - 0 | FC U Craiova 1948FC U Craiova |
| 11 Sep 21 | r08 | FC BotoșaniFC Botoșani | 1 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
| 12 Sep 21 | r08 | Gaz Metan MediașGaz Metan Med | 1 - 2 | FC VoluntariFC Voluntari |
| 12 Sep 21 | r08 | Steaua BucurestiSteaua Bucure | 6 - 0 | Dinamo Bucuresti Dinamo Bucure |
| 13 Sep 21 | r08 | Farul ConstantaFarul Constan | 5 - 0 | Academica ClinceniAcademica Cli |
| 13 Sep 21 | r08 | Universitatea CraiovaUniversitatea | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| |
| 17 Sep 21 | r09 | FC VoluntariFC Voluntari | 4 - 0 | CS MioveniCS Mioveni |
| 17 Sep 21 | r09 | Rapid BucurestiRapid Bucures | 1 - 2 | Gaz Metan MediașGaz Metan Med |
| 18 Sep 21 | r09 | Chindia TârgovișteChindia Târgo | 2 - 0 | Farul ConstantaFarul Constan |
| 18 Sep 21 | r09 | FC U Craiova 1948FC U Craiova | 0 - 1 | Steaua BucurestiSteaua Bucure |
| 19 Sep 21 | r09 | Academica ClinceniAcademica Cli | 0 - 1 | Arges PitestiArges Pitesti |
| 19 Sep 21 | r09 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 0 | Uta AradUta Arad |
| 19 Sep 21 | r09 | Dinamo Bucuresti Dinamo Bucure | 1 - 2 | FC BotoșaniFC Botoșani |
| 20 Sep 21 | r09 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Universitatea CraiovaUniversitatea |
| |
| 24 Sep 21 | r10 | Rapid BucurestiRapid Bucures | 0 - 1 | FC VoluntariFC Voluntari |
| 25 Sep 21 | r10 | Arges PitestiArges Pitesti | 0 - 0 | Chindia TârgovișteChindia Târgo |
| 25 Sep 21 | r10 | Steaua BucurestiSteaua Bucure | 3 - 2 | Academica ClinceniAcademica Cli |
| 26 Sep 21 | r10 | Farul ConstantaFarul Constan | 2 - 1 | CS MioveniCS Mioveni |
| 26 Sep 21 | r10 | FC BotoșaniFC Botoșani | 1 - 1 | FC U Craiova 1948FC U Craiova |
| 26 Sep 21 | r10 | Uta AradUta Arad | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 27 Sep 21 | r10 | Gaz Metan MediașGaz Metan Med | 0 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 27 Sep 21 | r10 | Universitatea CraiovaUniversitatea | 5 - 0 | Dinamo Bucuresti Dinamo Bucure |
| |
| 01 Oct 21 | r11 | CS MioveniCS Mioveni | 0 - 0 | Arges PitestiArges Pitesti |
| 01 Oct 21 | r11 | Chindia TârgovișteChindia Târgo | 0 - 1 | Steaua BucurestiSteaua Bucure |
| 02 Oct 21 | r11 | Dinamo Bucuresti Dinamo Bucure | 2 - 2 | Uta AradUta Arad |
| 02 Oct 21 | r11 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 2 - 2 | Rapid BucurestiRapid Bucures |
| 03 Oct 21 | r11 | FC VoluntariFC Voluntari | 1 - 0 | Farul ConstantaFarul Constan |
| 03 Oct 21 | r11 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Gaz Metan MediașGaz Metan Med |
| 03 Oct 21 | r11 | FC U Craiova 1948FC U Craiova | 0 - 2 | Universitatea CraiovaUniversitatea |
| 04 Oct 21 | r11 | Academica ClinceniAcademica Cli | 1 - 1 | FC BotoșaniFC Botoșani |
| |
| 15 Oct 21 | r12 | Gaz Metan MediașGaz Metan Med | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
| 16 Oct 21 | r12 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 1 - 2 | FC VoluntariFC Voluntari |
| 16 Oct 21 | r12 | Steaua BucurestiSteaua Bucure | 3 - 0 | CS MioveniCS Mioveni |
| 17 Oct 21 | r12 | Arges PitestiArges Pitesti | 2 - 1 | Farul ConstantaFarul Constan |
| 17 Oct 21 | r12 | Uta AradUta Arad | 1 - 0 | FC U Craiova 1948FC U Craiova |
| 17 Oct 21 | r12 | Rapid BucurestiRapid Bucures | 2 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
| 18 Oct 21 | r12 | FC BotoșaniFC Botoșani | 0 - 0 | Chindia TârgovișteChindia Târgo |
| 18 Oct 21 | r12 | Universitatea CraiovaUniversitatea | 5 - 0 | Academica ClinceniAcademica Cli |
| |
| 22 Oct 21 | r13 | FC U Craiova 1948FC U Craiova | 2 - 0 | Gaz Metan MediașGaz Metan Med |
| 22 Oct 21 | r13 | Chindia TârgovișteChindia Târgo | 0 - 1 | Universitatea CraiovaUniversitatea |
| 23 Oct 21 | r13 | FC VoluntariFC Voluntari | 0 - 2 | Arges PitestiArges Pitesti |
| 23 Oct 21 | r13 | CS MioveniCS Mioveni | 1 - 1 | FC BotoșaniFC Botoșani |
| 23 Oct 21 | r13 | Dinamo Bucuresti Dinamo Bucure | 1 - 1 | Rapid BucurestiRapid Bucures |
| 25 Oct 21 | r13 | Academica ClinceniAcademica Cli | 0 - 3 | Uta AradUta Arad |
| 25 Oct 21 | r13 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| |
| 29 Oct 21 | r14 | FC BotoșaniFC Botoșani | 0 - 2 | Farul ConstantaFarul Constan |
| 30 Oct 21 | r14 | Universitatea CraiovaUniversitatea | 5 - 2 | CS MioveniCS Mioveni |
| 30 Oct 21 | r14 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | FC VoluntariFC Voluntari |
| 31 Oct 21 | r14 | Gaz Metan MediașGaz Metan Med | 1 - 1 | Academica ClinceniAcademica Cli |
| 31 Oct 21 | r14 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 4 - 1 | Dinamo BucurestiDinamo Bucure |
| 31 Oct 21 | r14 | Steaua BucurestiSteaua Bucure | 2 - 1 | Arges PitestiArges Pitesti |
| 01 Nov 21 | r14 | Uta AradUta Arad | 0 - 2 | Chindia TârgovișteChindia Târgo |
| 01 Nov 21 | r14 | Rapid BucurestiRapid Bucures | 0 - 0 | FC U Craiova 1948FC U Craiova |
| |
| 04 Nov 21 | r13 | Farul ConstantaFarul Constan | 0 - 1 | Steaua BucurestiSteaua Bucure |
| |
| 05 Nov 21 | r15 | Chindia TârgovișteChindia Târgo | 0 - 1 | Gaz Metan MediașGaz Metan Med |
| 05 Nov 21 | r15 | Arges PitestiArges Pitesti | 0 - 1 | FC BotoșaniFC Botoșani |
| 06 Nov 21 | r15 | CS MioveniCS Mioveni | 0 - 0 | Uta AradUta Arad |
| 06 Nov 21 | r15 | FC U Craiova 1948FC U Craiova | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 07 Nov 21 | r15 | Farul ConstantaFarul Constan | 1 - 0 | Universitatea CraiovaUniversitatea |
| 07 Nov 21 | r15 | Dinamo Bucuresti Dinamo Bucure | 0 - 3 | CFR Cluj-NapocaCFR Cluj-Napo |
| 07 Nov 21 | r15 | FC VoluntariFC Voluntari | 0 - 0 | Steaua BucurestiSteaua Bucure |
| 08 Nov 21 | r15 | Academica ClinceniAcademica Cli | 2 - 3 | Rapid BucurestiRapid Bucures |
| |
| 19 Nov 21 | r16 | Academica ClinceniAcademica Cli | 0 - 2 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 19 Nov 21 | r16 | Chindia TârgovișteChindia Târgo | 2 - 2 | Rapid BucurestiRapid Bucures |
| 20 Nov 21 | r16 | Farul ConstantaFarul Constan | 0 - 0 | Uta AradUta Arad |
| 20 Nov 21 | r16 | FC U Craiova 1948FC U Craiova | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| 21 Nov 21 | r16 | Arges PitestiArges Pitesti | 3 - 2 | Universitatea CraiovaUniversitatea |
| 21 Nov 21 | r16 | Steaua BucurestiSteaua Bucure | 3 - 1 | FC BotoșaniFC Botoșani |
| 22 Nov 21 | r16 | CS MioveniCS Mioveni | 1 - 0 | Gaz Metan MediașGaz Metan Med |
| 22 Nov 21 | r16 | FC VoluntariFC Voluntari | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
| |
| 26 Nov 21 | r17 | Dinamo Bucuresti Dinamo Bucure | 0 - 0 | FC U Craiova 1948FC U Craiova |
| 27 Nov 21 | r17 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 0 | Chindia TârgovișteChindia Târgo |
| 27 Nov 21 | r17 | Uta AradUta Arad | 0 - 1 | Arges PitestiArges Pitesti |
| 27 Nov 21 | r17 | Rapid BucurestiRapid Bucures | 1 - 1 | CS MioveniCS Mioveni |
| 28 Nov 21 | r17 | FC BotoșaniFC Botoșani | 1 - 1 | FC VoluntariFC Voluntari |
| 28 Nov 21 | r17 | Universitatea CraiovaUniversitatea | 2 - 3 | Steaua BucurestiSteaua Bucure |
| 29 Nov 21 | r17 | Gaz Metan MediașGaz Metan Med | 1 - 1 | Farul ConstantaFarul Constan |
| 29 Nov 21 | r17 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Academica ClinceniAcademica Cli |
| |
| 03 Dec 21 | r18 | Academica ClinceniAcademica Cli | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
| 04 Dec 21 | r18 | Chindia TârgovișteChindia Târgo | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 04 Dec 21 | r18 | Farul ConstantaFarul Constan | 2 - 0 | Rapid BucurestiRapid Bucures |
| 05 Dec 21 | r18 | CS MioveniCS Mioveni | 0 - 2 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 05 Dec 21 | r18 | FC U Craiova 1948FC U Craiova | 0 - 2 | FC VoluntariFC Voluntari |
| 05 Dec 21 | r18 | Steaua BucurestiSteaua Bucure | 2 - 1 | Uta AradUta Arad |
| 06 Dec 21 | r18 | Arges PitestiArges Pitesti | 1 - 2 | Gaz Metan MediașGaz Metan Med |
| 06 Dec 21 | r18 | FC BotoșaniFC Botoșani | 2 - 2 | Universitatea CraiovaUniversitatea |
| |
| 10 Dec 21 | r19 | FC U Craiova 1948FC U Craiova | 1 - 2 | Academica ClinceniAcademica Cli |
| 10 Dec 21 | r19 | Rapid BucurestiRapid Bucures | 2 - 0 | Arges PitestiArges Pitesti |
| 11 Dec 21 | r19 | Uta AradUta Arad | 0 - 0 | FC BotoșaniFC Botoșani |
| 11 Dec 21 | r19 | FC VoluntariFC Voluntari | 1 - 1 | Universitatea CraiovaUniversitatea |
| 11 Dec 21 | r19 | Gaz Metan MediașGaz Metan Med | 0 - 1 | Steaua BucurestiSteaua Bucure |
| 12 Dec 21 | r19 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 1 - 0 | Farul ConstantaFarul Constan |
| 12 Dec 21 | r19 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | CS MioveniCS Mioveni |
| 13 Dec 21 | r19 | Dinamo Bucuresti Dinamo Bucure | 1 - 0 | Chindia TârgovișteChindia Târgo |
| |
| 14 Dec 21 | r20 | Academica ClinceniAcademica Cli | 0 - 0 | FC VoluntariFC Voluntari |
| 14 Dec 21 | r20 | Universitatea CraiovaUniversitatea | 0 - 0 | Uta AradUta Arad |
| 15 Dec 21 | r20 | FC BotoșaniFC Botoșani | 2 - 1 | Gaz Metan MediașGaz Metan Med |
| 15 Dec 21 | r20 | Arges PitestiArges Pitesti | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 15 Dec 21 | r20 | Steaua BucurestiSteaua Bucure | 3 - 1 | Rapid BucurestiRapid Bucures |
| 16 Dec 21 | r20 | Chindia TârgovișteChindia Târgo | 0 - 3 | FC U Craiova 1948FC U Craiova |
| 16 Dec 21 | r20 | CS MioveniCS Mioveni | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
| 16 Dec 21 | r20 | Farul ConstantaFarul Constan | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| |
| 17 Dec 21 | r21 | FC VoluntariFC Voluntari | 2 - 1 | Uta AradUta Arad |
| 18 Dec 21 | r21 | Gaz Metan MediașGaz Metan Med | 1 - 1 | Universitatea CraiovaUniversitatea |
| 18 Dec 21 | r21 | Rapid BucurestiRapid Bucures | 1 - 1 | FC BotoșaniFC Botoșani |
| 19 Dec 21 | r21 | Academica ClinceniAcademica Cli | 0 - 1 | Chindia TârgovișteChindia Târgo |
| 19 Dec 21 | r21 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Arges PitestiArges Pitesti |
| 19 Dec 21 | r21 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 0 | Steaua BucurestiSteaua Bucure |
| 20 Dec 21 | r21 | FC U Craiova 1948FC U Craiova | 0 - 0 | CS MioveniCS Mioveni |
| 20 Dec 21 | r21 | Dinamo Bucuresti Dinamo Bucure | 0 - 2 | Farul ConstantaFarul Constan |
| |
| 21 Jan 22 | r22 | Arges PitestiArges Pitesti | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
| 22 Jan 22 | r22 | Chindia TârgovișteChindia Târgo | 0 - 0 | FC VoluntariFC Voluntari |
| 22 Jan 22 | r22 | Universitatea CraiovaUniversitatea | 1 - 0 | Rapid BucurestiRapid Bucures |
| 23 Jan 22 | r22 | CS MioveniCS Mioveni | 3 - 1 | Academica ClinceniAcademica Cli |
| 23 Jan 22 | r22 | Uta AradUta Arad | 0 - 1 | Gaz Metan MediașGaz Metan Med |
| 23 Jan 22 | r22 | Steaua BucurestiSteaua Bucure | 3 - 3 | CFR Cluj-NapocaCFR Cluj-Napo |
| 24 Jan 22 | r22 | FC BotoșaniFC Botoșani | 1 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 24 Jan 22 | r22 | Farul ConstantaFarul Constan | 3 - 2 | FC U Craiova 1948FC U Craiova |
| |
| 28 Jan 22 | r23 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 3 - 1 | Universitatea CraiovaUniversitatea |
| 29 Jan 22 | r23 | FC VoluntariFC Voluntari | 3 - 1 | Gaz Metan MediașGaz Metan Med |
| 29 Jan 22 | r23 | Rapid BucurestiRapid Bucures | 1 - 1 | Uta AradUta Arad |
| 30 Jan 22 | r23 | Chindia TârgovișteChindia Târgo | 0 - 0 | CS MioveniCS Mioveni |
| 30 Jan 22 | r23 | FC U Craiova 1948FC U Craiova | 1 - 0 | Arges PitestiArges Pitesti |
| 30 Jan 22 | r23 | Dinamo Bucuresti Dinamo Bucure | 0 - 3 | Steaua BucurestiSteaua Bucure |
| 31 Jan 22 | r23 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 1 | FC BotoșaniFC Botoșani |
| |
| 04 Feb 22 | r24 | CS MioveniCS Mioveni | 0 - 0 | FC VoluntariFC Voluntari |
| 04 Feb 22 | r24 | Gaz Metan MediașGaz Metan Med | 1 - 1 | Rapid BucurestiRapid Bucures |
| 05 Feb 22 | r24 | Uta AradUta Arad | 1 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 05 Feb 22 | r24 | Farul ConstantaFarul Constan | 0 - 1 | Chindia TârgovișteChindia Târgo |
| 05 Feb 22 | r24 | Universitatea CraiovaUniversitatea | 1 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 06 Feb 22 | r24 | Arges PitestiArges Pitesti | 1 - 0 | Academica ClinceniAcademica Cli |
| 06 Feb 22 | r24 | Steaua BucurestiSteaua Bucure | 2 - 2 | FC U Craiova 1948FC U Craiova |
| 07 Feb 22 | r24 | FC BotoșaniFC Botoșani | 4 - 0 | Dinamo Bucuresti Dinamo Bucure |
| |
| 08 Feb 22 | r25 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 2 - 0 | Gaz Metan MediașGaz Metan Med |
| 08 Feb 22 | r25 | CFR Cluj-NapocaCFR Cluj-Napo | 0 - 0 | Uta AradUta Arad |
| 08 Feb 22 | r25 | FC VoluntariFC Voluntari | 0 - 0 | Rapid BucurestiRapid Bucures |
| 09 Feb 22 | r25 | Chindia TârgovișteChindia Târgo | 1 - 1 | Arges PitestiArges Pitesti |
| 09 Feb 22 | r25 | CS MioveniCS Mioveni | 1 - 1 | Farul ConstantaFarul Constan |
| 09 Feb 22 | r25 | Academica ClinceniAcademica Cli | 0 - 3 | Steaua BucurestiSteaua Bucure |
| 10 Feb 22 | r25 | FC U Craiova 1948FC U Craiova | 3 - 2 | FC BotoșaniFC Botoșani |
| 10 Feb 22 | r25 | Dinamo Bucuresti Dinamo Bucure | 1 - 6 | Universitatea CraiovaUniversitatea |
| |
| 11 Feb 22 | r26 | Rapid BucurestiRapid Bucures | 1 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 12 Feb 22 | r26 | Farul ConstantaFarul Constan | 3 - 0 | FC VoluntariFC Voluntari |
| 12 Feb 22 | r26 | Gaz Metan MediașGaz Metan Med | 1 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| 13 Feb 22 | r26 | Arges PitestiArges Pitesti | 1 - 0 | CS MioveniCS Mioveni |
| 13 Feb 22 | r26 | Uta AradUta Arad | 0 - 0 | Dinamo Bucuresti Dinamo Bucure |
| 13 Feb 22 | r26 | Steaua BucurestiSteaua Bucure | 3 - 2 | Chindia TârgovișteChindia Târgo |
| 14 Feb 22 | r26 | FC BotoșaniFC Botoșani | 2 - 0 | Academica ClinceniAcademica Cli |
| 14 Feb 22 | r26 | Universitatea CraiovaUniversitatea | 2 - 0 | FC U Craiova 1948FC U Craiova |
| |
| 17 Feb 22 | r23 | Academica ClinceniAcademica Cli | 2 - 8 | Farul ConstantaFarul Constan |
| |
| 18 Feb 22 | r27 | FC U Craiova 1948FC U Craiova | 1 - 1 | Uta AradUta Arad |
| 18 Feb 22 | r27 | Dinamo Bucuresti Dinamo Bucure | 4 - 0 | Gaz Metan MediașGaz Metan Med |
| 19 Feb 22 | r27 | FC VoluntariFC Voluntari | 3 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 19 Feb 22 | r27 | CS MioveniCS Mioveni | 1 - 1 | Steaua BucurestiSteaua Bucure |
| 20 Feb 22 | r27 | Chindia TârgovișteChindia Târgo | 1 - 1 | FC BotoșaniFC Botoșani |
| 20 Feb 22 | r27 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Rapid BucurestiRapid Bucures |
| 21 Feb 22 | r27 | Farul ConstantaFarul Constan | 0 - 1 | Arges PitestiArges Pitesti |
| 21 Feb 22 | r27 | Academica ClinceniAcademica Cli | 1 - 3 | Universitatea CraiovaUniversitatea |
| |
| 25 Feb 22 | r28 | Uta AradUta Arad | 2 - 0 | Academica ClinceniAcademica Cli |
| 25 Feb 22 | r28 | Universitatea CraiovaUniversitatea | 1 - 0 | Chindia TârgovișteChindia Târgo |
| 26 Feb 22 | r28 | Gaz Metan MediașGaz Metan Med | 0 - 3 | FC U Craiova 1948FC U Craiova |
| 26 Feb 22 | r28 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 0 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| 26 Feb 22 | r28 | Rapid BucurestiRapid Bucures | 1 - 1 | Dinamo Bucuresti Dinamo Bucure |
| 27 Feb 22 | r28 | Arges PitestiArges Pitesti | 0 - 0 | FC VoluntariFC Voluntari |
| 27 Feb 22 | r28 | FC BotoșaniFC Botoșani | 0 - 0 | CS MioveniCS Mioveni |
| 27 Feb 22 | r28 | Steaua BucurestiSteaua Bucure | 0 - 2 | Farul ConstantaFarul Constan |
| |
| 01 Mar 22 | r29 | Chindia TârgovișteChindia Târgo | 1 - 0 | Uta AradUta Arad |
| 01 Mar 22 | r29 | Dinamo Bucuresti Dinamo Bucure | 1 - 3 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 01 Mar 22 | r29 | FC U Craiova 1948FC U Craiova | 3 - 2 | Rapid BucurestiRapid Bucures |
| 02 Mar 22 | r29 | Academica ClinceniAcademica Cli | 2 - 0 | Gaz Metan MediașGaz Metan Med |
| 02 Mar 22 | r29 | CS MioveniCS Mioveni | 0 - 3 | Universitatea CraiovaUniversitatea |
| 02 Mar 22 | r29 | FC VoluntariFC Voluntari | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 03 Mar 22 | r29 | Farul ConstantaFarul Constan | 2 - 0 | FC BotoșaniFC Botoșani |
| 03 Mar 22 | r29 | Arges PitestiArges Pitesti | 1 - 0 | Steaua BucurestiSteaua Bucure |
| |
| 04 Mar 22 | r30 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 2 - 1 | FC U Craiova 1948FC U Craiova |
| 05 Mar 22 | r30 | Uta AradUta Arad | 2 - 1 | CS MioveniCS Mioveni |
| 05 Mar 22 | r30 | Rapid BucurestiRapid Bucures | 1 - 0 | Academica ClinceniAcademica Cli |
| 06 Mar 22 | r30 | Gaz Metan MediașGaz Metan Med | 0 - 4 | Chindia TârgovișteChindia Târgo |
| 06 Mar 22 | r30 | CFR Cluj-NapocaCFR Cluj-Napo | 4 - 1 | Dinamo Bucuresti Dinamo Bucure |
| 06 Mar 22 | r30 | Steaua BucurestiSteaua Bucure | 1 - 0 | FC VoluntariFC Voluntari |
| 07 Mar 22 | r30 | FC BotoșaniFC Botoșani | 1 - 2 | Arges PitestiArges Pitesti |
| 07 Mar 22 | r30 | Universitatea CraiovaUniversitatea | 1 - 0 | Farul ConstantaFarul Constan |
| |
| 11 Mar 22 | r01 | Uta AradUta Arad | 3 - 0 | Academica ClinceniAcademica Cli |
| 11 Mar 22 | r01 | Universitatea CraiovaUniversitatea | 3 - 0 | Arges PitestiArges Pitesti |
| 12 Mar 22 | r01 | Chindia TârgovișteChindia Târgo | 0 - 0 | FC U Craiova 1948FC U Craiova |
| 12 Mar 22 | r01 | CFR Cluj-NapocaCFR Cluj-Napo | 3 - 1 | FC VoluntariFC Voluntari |
| 13 Mar 22 | r01 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 3 - 1 | CS MioveniCS Mioveni |
| 13 Mar 22 | r01 | Rapid BucurestiRapid Bucures | 3 - 1 | Dinamo BucurestiDinamo Bucure |
| 14 Mar 22 | r01 | FC BotoșaniFC Botoșani | 5 - 0 | Gaz Metan MediașGaz Metan Med |
| 14 Mar 22 | r01 | Steaua BucurestiSteaua Bucure | 2 - 0 | Farul ConstantaFarul Constan |
| |
| 18 Mar 22 | r02 | FC BotoșaniFC Botoșani | 1 - 0 | Uta AradUta Arad |
| 18 Mar 22 | r02 | FC VoluntariFC Voluntari | 3 - 1 | Universitatea CraiovaUniversitatea |
| 19 Mar 22 | r02 | Gaz Metan MediașGaz Metan Med | 0 - 2 | FC U Craiova 1948FC U Craiova |
| 19 Mar 22 | r02 | Academica ClinceniAcademica Cli | 0 - 1 | Rapid BucurestiRapid Bucures |
| 19 Mar 22 | r02 | Farul ConstantaFarul Constan | 0 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
| 20 Mar 22 | r02 | Dinamo BucurestiDinamo Bucure | 0 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 20 Mar 22 | r02 | Arges PitestiArges Pitesti | 2 - 3 | Steaua BucurestiSteaua Bucure |
| 21 Mar 22 | r02 | CS MioveniCS Mioveni | 1 - 0 | Chindia TârgovișteChindia Târgo |
| |
| 01 Apr 22 | r03 | FC U Craiova 1948FC U Craiova | 1 - 1 | CS MioveniCS Mioveni |
| 01 Apr 22 | r03 | Chindia TârgovișteChindia Târgo | 0 - 2 | Dinamo BucurestiDinamo Bucure |
| 02 Apr 22 | r03 | Uta AradUta Arad | 4 - 0 | Gaz Metan MediașGaz Metan Med |
| 02 Apr 22 | r03 | FC VoluntariFC Voluntari | 1 - 0 | Farul ConstantaFarul Constan |
| 02 Apr 22 | r03 | Rapid BucurestiRapid Bucures | 3 - 0 | FC BotoșaniFC Botoșani |
| 03 Apr 22 | r03 | Steaua BucurestiSteaua Bucure | 0 - 2 | Universitatea CraiovaUniversitatea |
| 04 Apr 22 | r03 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 6 - 0 | Academica ClinceniAcademica Cli |
| 04 Apr 22 | r03 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | Arges PitestiArges Pitesti |
| |
| 08 Apr 22 | r04 | Academica ClinceniAcademica Cli | 0 - 3 | Chindia TârgovișteChindia Târgo |
| 08 Apr 22 | r04 | Dinamo BucurestiDinamo Bucure | 1 - 2 | FC U Craiova 1948FC U Craiova |
| 09 Apr 22 | r04 | Arges PitestiArges Pitesti | 0 - 2 | Farul ConstantaFarul Constan |
| 09 Apr 22 | r04 | Uta AradUta Arad | 0 - 2 | Rapid BucurestiRapid Bucures |
| 10 Apr 22 | r04 | FC BotoșaniFC Botoșani | 0 - 1 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 10 Apr 22 | r04 | Universitatea CraiovaUniversitatea | 3 - 2 | CFR Cluj-NapocaCFR Cluj-Napo |
| 11 Apr 22 | r04 | Gaz Metan MediașGaz Metan Med | 1 - 2 | CS MioveniCS Mioveni |
| 11 Apr 22 | r04 | Steaua BucurestiSteaua Bucure | 4 - 0 | FC VoluntariFC Voluntari |
| |
| 15 Apr 22 | r05 | Chindia TârgovișteChindia Târgo | 1 - 2 | FC BotoșaniFC Botoșani |
| 15 Apr 22 | r05 | CS MioveniCS Mioveni | 2 - 0 | Dinamo BucurestiDinamo Bucure |
| 16 Apr 22 | r05 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 1 - 0 | Uta AradUta Arad |
| 16 Apr 22 | r05 | FC VoluntariFC Voluntari | 0 - 1 | Arges PitestiArges Pitesti |
| 16 Apr 22 | r05 | Farul ConstantaFarul Constan | 0 - 3 | Universitatea CraiovaUniversitatea |
| 17 Apr 22 | r05 | FC U Craiova 1948FC U Craiova | 4 - 0 | Academica ClinceniAcademica Cli |
| 17 Apr 22 | r05 | CFR Cluj-NapocaCFR Cluj-Napo | 0 - 1 | Steaua BucurestiSteaua Bucure |
| 18 Apr 22 | r05 | Rapid BucurestiRapid Bucures | 8 - 0 | Gaz Metan MediașGaz Metan Med |
| |
| 22 Apr 22 | r06 | Academica ClinceniAcademica Cli | 0 - 2 | CS MioveniCS Mioveni |
| 22 Apr 22 | r06 | Gaz Metan MediașGaz Metan Med | 0 - 1 | Dinamo BucurestiDinamo Bucure |
| 23 Apr 22 | r06 | Uta AradUta Arad | 1 - 0 | Chindia TârgovișteChindia Târgo |
| 23 Apr 22 | r06 | Rapid BucurestiRapid Bucures | 1 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 24 Apr 22 | r06 | FC VoluntariFC Voluntari | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 25 Apr 22 | r06 | FC BotoșaniFC Botoșani | 2 - 1 | FC U Craiova 1948FC U Craiova |
| 25 Apr 22 | r06 | Arges PitestiArges Pitesti | 0 - 4 | Universitatea CraiovaUniversitatea |
| 25 Apr 22 | r06 | Farul ConstantaFarul Constan | 0 - 4 | Steaua BucurestiSteaua Bucure |
| |
| 29 Apr 22 | r07 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 3 - 1 | Gaz Metan MediașGaz Metan Med |
| 29 Apr 22 | r07 | Chindia TârgovișteChindia Târgo | 0 - 0 | Rapid BucurestiRapid Bucures |
| 30 Apr 22 | r07 | Dinamo BucurestiDinamo Bucure | 5 - 1 | Academica ClinceniAcademica Cli |
| 30 Apr 22 | r07 | Universitatea CraiovaUniversitatea | 1 - 0 | FC VoluntariFC Voluntari |
| 01 May 22 | r07 | FC U Craiova 1948FC U Craiova | 1 - 0 | Uta AradUta Arad |
| 01 May 22 | r07 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | Farul ConstantaFarul Constan |
| 02 May 22 | r07 | CS MioveniCS Mioveni | 0 - 2 | FC BotoșaniFC Botoșani |
| 02 May 22 | r07 | Steaua BucurestiSteaua Bucure | 4 - 0 | Arges PitestiArges Pitesti |
| |
| 06 May 22 | r08 | Gaz Metan MediașGaz Metan Med | 4 - 3 | Academica ClinceniAcademica Cli |
| 06 May 22 | r08 | FC BotoșaniFC Botoșani | 2 - 3 | Dinamo BucurestiDinamo Bucure |
| 07 May 22 | r08 | Uta AradUta Arad | 1 - 0 | CS MioveniCS Mioveni |
| 07 May 22 | r08 | Farul ConstantaFarul Constan | 1 - 1 | FC VoluntariFC Voluntari |
| 07 May 22 | r08 | Arges PitestiArges Pitesti | 0 - 6 | CFR Cluj-NapocaCFR Cluj-Napo |
| 08 May 22 | r08 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 2 - 1 | Chindia TârgovișteChindia Târgo |
| 08 May 22 | r08 | Universitatea CraiovaUniversitatea | 0 - 1 | Steaua BucurestiSteaua Bucure |
| 09 May 22 | r08 | Rapid BucurestiRapid Bucures | 2 - 3 | FC U Craiova 1948FC U Craiova |
| |
| 13 May 22 | r09 | Chindia TârgovișteChindia Târgo | 3 - 0 | Gaz Metan MediașGaz Metan Med |
| 13 May 22 | r09 | Dinamo BucurestiDinamo Bucure | 1 - 1 | Uta AradUta Arad |
| 14 May 22 | r09 | Farul ConstantaFarul Constan | 1 - 0 | Arges PitestiArges Pitesti |
| 14 May 22 | r09 | FC VoluntariFC Voluntari | 2 - 2 | Steaua BucurestiSteaua Bucure |
| 15 May 22 | r09 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 1 | Universitatea CraiovaUniversitatea |
| 16 May 22 | r09 | FC U Craiova 1948FC U Craiova | 0 - 5 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
| 16 May 22 | r09 | CS MioveniCS Mioveni | 3 - 2 | Rapid BucurestiRapid Bucures |
| 16 May 22 | r09 | Academica ClinceniAcademica Cli | 0 - 4 | FC BotoșaniFC Botoșani |
| |
| 20 May 22 | r10 | Universitatea CraiovaUniversitatea | 4 - 1 | Farul ConstantaFarul Constan |
| 22 May 22 | r10 | Steaua BucurestiSteaua Bucure | 3 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 23 May 22 | r10 | Arges PitestiArges Pitesti | 0 - 1 | FC VoluntariFC Voluntari |
| |
| 23 May 22 | r00 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | - | FC BotoșaniFC Botoșani |
| 27 May 22 | r00 | Universitatea CraiovaUniversitatea | 2 - 0 | FC BotoșaniFC Botoșani |
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Botoșani
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Csíkszereda Miercurea Ciuc
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Metaloglobus București
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