| 31 Jul 21 | r01   | Kispest HonvedKispest Honve | 1 - 4 | DebrecenDebrecen |
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| 08 Aug 21 | r02  | DebrecenDebrecen | 2 - 2 | Újpest FCÚjpest FC |
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| 14 Aug 21 | r03 | Paksi FCPaksi FC | 3 - 3 | DebrecenDebrecen |
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| 21 Aug 21 | r04 | DebrecenDebrecen | 1 - 2 | Zalaegerszegi TEZalaegerszegi |
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| 28 Aug 21 | r05 | FerencvarosFerencvaros | 4 - 2 | DebrecenDebrecen |
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| 10 Sep 21 | r06 | DebrecenDebrecen | 5 - 0 | GyirmótGyirmót |
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| 26 Sep 21 | r07 | Kisvárda FCKisvárda FC | 2 - 1 | DebrecenDebrecen |
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| 02 Oct 21 | r08 | DebrecenDebrecen | 1 - 1 | Videoton FC FehervarVideoton FC F |
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| 17 Oct 21 | r09 | Mezőkövesdi SEMezőkövesdi S | 1 - 0 | DebrecenDebrecen |
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| 24 Oct 21 | r10 | DebrecenDebrecen | 0 - 3 | Puskás Akadémia FCPuskás Akadém |
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| 30 Oct 21 | r11 | MTK HungariaMTK Hungaria | 1 - 1 | DebrecenDebrecen |
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| 06 Nov 21 | r12 | DebrecenDebrecen | 5 - 3 | Kispest HonvedKispest Honve |
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| 20 Nov 21 | r13 | Újpest FCÚjpest FC | 3 - 1 | DebrecenDebrecen |
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| 28 Nov 21 | r14 | DebrecenDebrecen | 1 - 1 | Paksi FCPaksi FC |
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| 04 Dec 21 | r15 | Zalaegerszegi TEZalaegerszegi | 2 - 1 | DebrecenDebrecen |
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| 12 Dec 21 | r16 | DebrecenDebrecen | 2 - 0 | FerencvarosFerencvaros |
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| 19 Dec 21 | r17 | GyirmótGyirmót | 0 - 0 | DebrecenDebrecen |
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| 29 Jan 22 | r18 | DebrecenDebrecen | 0 - 0 | Kisvárda FCKisvárda FC |
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| 05 Feb 22 | r19 | Videoton FC FehervarVideoton FC F | 1 - 2 | DebrecenDebrecen |
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| 12 Feb 22 | r20 | DebrecenDebrecen | 1 - 4 | Mezőkövesdi SEMezőkövesdi S |
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| 20 Feb 22 | r21 | Puskás Akadémia FCPuskás Akadém | 0 - 2 | DebrecenDebrecen |
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| 27 Feb 22 | r22 | DebrecenDebrecen | 1 - 0 | MTK HungariaMTK Hungaria |
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| 05 Mar 22 | r23 | Kispest HonvedKispest Honve | 4 - 2 | DebrecenDebrecen |
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| 12 Mar 22 | r24 | DebrecenDebrecen | 1 - 2 | Újpest FCÚjpest FC |
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| 20 Mar 22 | r25 | Paksi FCPaksi FC | 0 - 1 | DebrecenDebrecen |
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| 02 Apr 22 | r26 | DebrecenDebrecen | 0 - 0 | Zalaegerszegi TEZalaegerszegi |
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| 09 Apr 22 | r27 | FerencvarosFerencvaros | 3 - 0 | DebrecenDebrecen |
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| 15 Apr 22 | r28 | DebrecenDebrecen | 3 - 1 | GyirmótGyirmót |
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| 23 Apr 22 | r29 | Kisvárda FCKisvárda FC | 1 - 0 | DebrecenDebrecen |
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| 30 Apr 22 | r30 | DebrecenDebrecen | 0 - 3 | Videoton FC FehervarVideoton FC F |
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| 03 May 22 | r31 | Mezőkövesdi SEMezőkövesdi S | 0 - 1 | DebrecenDebrecen |
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| 07 May 22 | r32 | DebrecenDebrecen | 1 - 1 | Puskás Akadémia FCPuskás Akadém |
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| 15 May 22 | r33 | MTK HungariaMTK Hungaria | 3 - 0 | DebrecenDebrecen |
Team 2021-2022 Schedules
Budapest Honvéd
Debrecen
Ferencváros
Győri ETO
Kisvárda
MTK Budapest
Nyíregyháza
Paks
Puskás Akadémia
Újpest
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