| 25 Jul 21 | r01    | MFK Zemplín MichalovceMFK Zemplín M | 4 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 01 Aug 21 | r02 | DAC 1904 Dunajská StredaDAC 1904 Duna | 3 - 1 | Tatran Liptovský MikulášTatran Liptov |
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| 08 Aug 21 | r03 | ŠKF SereďŠKF Sereď | 1 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 14 Aug 21 | r04 | FK Senica FK Senica | 1 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 22 Aug 21 | r05 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 1 | TrencinTrencin |
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| 27 Aug 21 | r06 | FK PohronieFK Pohronie | 0 - 3 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 12 Sep 21 | r07 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 1 | Slovan BratislavaSlovan Bratis |
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| 18 Sep 21 | r08 | MFK RužomberokMFK Ružombero | 1 - 2 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 26 Sep 21 | r09  | DAC 1904 Dunajská StredaDAC 1904 Duna | 0 - 3 | FC Spartak TrnavaFC Spartak Tr |
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| 01 Oct 21 | r10 | DAC 1904 Dunajská StredaDAC 1904 Duna | 4 - 2 | ViOn Zlaté MoravceViOn Zlaté Mo |
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| 16 Oct 21 | r11 | MSK ZilinaMSK Zilina | 0 - 2 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 24 Oct 21 | r12 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 0 | MFK Zemplín MichalovceMFK Zemplín M |
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| 30 Oct 21 | r13 | Tatran Liptovský MikulášTatran Liptov | 1 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 06 Nov 21 | r14 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 3 | ŠKF SereďŠKF Sereď |
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| 20 Nov 21 | r15 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 0 | FK Senica FK Senica |
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| 27 Nov 21 | r16 | TrencinTrencin | 0 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 04 Dec 21 | r17 | DAC 1904 Dunajská StredaDAC 1904 Duna | 2 - 0 | FK PohronieFK Pohronie |
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| 12 Dec 21 | r18 | Slovan BratislavaSlovan Bratis | 0 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 17 Dec 21 | r19 | DAC 1904 Dunajská StredaDAC 1904 Duna | 0 - 0 | MFK RužomberokMFK Ružombero |
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| 13 Feb 22 | r20 | FC Spartak TrnavaFC Spartak Tr | 1 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 18 Feb 22 | r21 | ViOn Zlaté MoravceViOn Zlaté Mo | 2 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 26 Feb 22 | r22 | DAC 1904 Dunajská StredaDAC 1904 Duna | 3 - 1 | MSK ZilinaMSK Zilina |
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| 04 Mar 22 | r01 | MFK RužomberokMFK Ružombero | 4 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 13 Mar 22 | r02 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 19 Mar 22 | r03 | MSK ZilinaMSK Zilina | 2 - 2 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 02 Apr 22 | r04 | DAC 1904 Dunajská StredaDAC 1904 Duna | 0 - 0 | ŠKF SereďŠKF Sereď |
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| 10 Apr 22 | r05 | Slovan BratislavaSlovan Bratis | 3 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 16 Apr 22 | r06 | DAC 1904 Dunajská StredaDAC 1904 Duna | 2 - 0 | MSK ZilinaMSK Zilina |
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| 24 Apr 22 | r07 | DAC 1904 Dunajská StredaDAC 1904 Duna | 2 - 0 | Slovan BratislavaSlovan Bratis |
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| 30 Apr 22 | r08 | ŠKF SereďŠKF Sereď | 0 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 15 May 22 | r09 | DAC 1904 Dunajská StredaDAC 1904 Duna | 2 - 3 | MFK RužomberokMFK Ružombero |
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| 21 May 22 | r10 | FC Spartak TrnavaFC Spartak Tr | 1 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 24 May 22 | r00 | DAC 1904 Dunajská StredaDAC 1904 Duna | 4 - 2 | TrencinTrencin |
| 27 May 22 | r00 | DAC 1904 Dunajská StredaDAC 1904 Duna | 2 - 1 | TrencinTrencin |
| 27 May 22 | r00 | TrencinTrencin | 2 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
Team 2021-2022 Schedules
DAC 1904 Dunajská Streda
Komárno
Košice
MSK Zilina
Ružomberok
Skalica
Slovan Bratislava
Spartak Trnava
Tatran Prešov
Trenčín
Železiarne Podbrezová
Zemplín Michalovce
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List
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