| 25 Jul 21 | r01    | FC Spartak TrnavaFC Spartak Tr | 2 - 0 | FK PohronieFK Pohronie |
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| 01 Aug 21 | r02 | FK Senica FK Senica | 2 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 09 Aug 21 | r03 | FC Spartak TrnavaFC Spartak Tr | 4 - 0 | Tatran Liptovský MikulášTatran Liptov |
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| 15 Aug 21 | r04 | FC Spartak TrnavaFC Spartak Tr | 2 - 0 | ViOn Zlaté MoravceViOn Zlaté Mo |
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| 21 Aug 21 | r05 | MFK RužomberokMFK Ružombero | 0 - 0 | FC Spartak TrnavaFC Spartak Tr |
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| 29 Aug 21 | r06 | FC Spartak TrnavaFC Spartak Tr | 1 - 1 | MSK ZilinaMSK Zilina |
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| 11 Sep 21 | r07 | MFK Zemplín MichalovceMFK Zemplín M | 1 - 2 | FC Spartak TrnavaFC Spartak Tr |
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| 17 Sep 21 | r08  | FC Spartak TrnavaFC Spartak Tr | 2 - 0 | ŠKF SereďŠKF Sereď |
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| 26 Sep 21 | r09 | DAC 1904 Dunajská StredaDAC 1904 Duna | 0 - 3 | FC Spartak TrnavaFC Spartak Tr |
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| 03 Oct 21 | r10 | TrencinTrencin | 0 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 17 Oct 21 | r11 | FC Spartak TrnavaFC Spartak Tr | 0 - 3 | Slovan BratislavaSlovan Bratis |
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| 23 Oct 21 | r12 | FK PohronieFK Pohronie | 0 - 2 | FC Spartak TrnavaFC Spartak Tr |
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| 29 Oct 21 | r13 | FC Spartak TrnavaFC Spartak Tr | 2 - 1 | FK Senica FK Senica |
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| 07 Nov 21 | r14 | Tatran Liptovský MikulášTatran Liptov | 0 - 2 | FC Spartak TrnavaFC Spartak Tr |
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| 20 Nov 21 | r15 | ViOn Zlaté MoravceViOn Zlaté Mo | 0 - 0 | FC Spartak TrnavaFC Spartak Tr |
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| 28 Nov 21 | r16 | FC Spartak TrnavaFC Spartak Tr | 0 - 3 | MFK RužomberokMFK Ružombero |
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| 05 Dec 21 | r17 | MSK ZilinaMSK Zilina | 0 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 10 Dec 21 | r18 | FC Spartak TrnavaFC Spartak Tr | 2 - 0 | MFK Zemplín MichalovceMFK Zemplín M |
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| 18 Dec 21 | r19 | ŠKF SereďŠKF Sereď | 0 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 13 Feb 22 | r20 | FC Spartak TrnavaFC Spartak Tr | 1 - 1 | DAC 1904 Dunajská StredaDAC 1904 Duna |
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| 19 Feb 22 | r21 | FC Spartak TrnavaFC Spartak Tr | 0 - 0 | TrencinTrencin |
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| 26 Feb 22 | r22 | Slovan BratislavaSlovan Bratis | 0 - 0 | FC Spartak TrnavaFC Spartak Tr |
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| 05 Mar 22 | r01 | FC Spartak TrnavaFC Spartak Tr | 0 - 1 | ŠKF SereďŠKF Sereď |
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| 13 Mar 22 | r02 | DAC 1904 Dunajská StredaDAC 1904 Duna | 1 - 1 | FC Spartak TrnavaFC Spartak Tr |
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| 20 Mar 22 | r03 | MFK RužomberokMFK Ružombero | 0 - 0 | FC Spartak TrnavaFC Spartak Tr |
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| 03 Apr 22 | r04 | FC Spartak TrnavaFC Spartak Tr | 0 - 1 | Slovan BratislavaSlovan Bratis |
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| 09 Apr 22 | r05 | FC Spartak TrnavaFC Spartak Tr | 1 - 0 | MSK ZilinaMSK Zilina |
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| 17 Apr 22 | r06 | ŠKF SereďŠKF Sereď | 0 - 2 | FC Spartak TrnavaFC Spartak Tr |
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| 24 Apr 22 | r07 | FC Spartak TrnavaFC Spartak Tr | 0 - 0 | MFK RužomberokMFK Ružombero |
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| 01 May 22 | r08 | Slovan BratislavaSlovan Bratis | 1 - 0 | FC Spartak TrnavaFC Spartak Tr |
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| 14 May 22 | r09 | MSK ZilinaMSK Zilina | 1 - 2 | FC Spartak TrnavaFC Spartak Tr |
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| 21 May 22 | r10 | FC Spartak TrnavaFC Spartak Tr | 1 - 0 | DAC 1904 Dunajská StredaDAC 1904 Duna |
Team 2021-2022 Schedules
DAC 1904 Dunajská Streda
Komárno
Košice
MSK Zilina
Ružomberok
Skalica
Slovan Bratislava
Spartak Trnava
Tatran Prešov
Trenčín
Železiarne Podbrezová
Zemplín Michalovce
League Table
List
Poster
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