| 06 Aug 22 | r01  | StrugaStruga | 3 - 0 | PobedaPobeda |
| |
| 14 Aug 22 | r02 | Bregalnica ŠtipBregalnica Št | 0 - 1 | StrugaStruga |
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| 21 Aug 22 | r03 | StrugaStruga | 2 - 1 | RabotnichkiRabotnichki |
| |
| 28 Aug 22 | r04 | Shkendija 79Shkendija 79 | 0 - 2 | StrugaStruga |
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| 31 Aug 22 | r05 | StrugaStruga | 2 - 1 | SileksSileks |
| |
| 04 Sep 22 | r06 | Akademija PandevAkademija Pan | 0 - 3 | StrugaStruga |
| |
| 11 Sep 22 | r07 | StrugaStruga | 3 - 0 | SkopjeSkopje |
| |
| 17 Sep 22 | r08 | StrugaStruga | 2 - 0 | TikvešTikveš |
| |
| 01 Oct 22 | r09 | Makedonija GjPMakedonija Gj | 1 - 1 | StrugaStruga |
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| 09 Oct 22 | r10 | StrugaStruga | - | RenovaRenova |
| |
| 16 Oct 22 | r11 | ShkupiShkupi | 1 - 0 | StrugaStruga |
| |
| 26 Oct 22 | r12 | PobedaPobeda | 2 - 0 | StrugaStruga |
| |
| 30 Oct 22 | r13 | StrugaStruga | 2 - 2 | Bregalnica ŠtipBregalnica Št |
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| 06 Nov 22 | r14 | RabotnichkiRabotnichki | 1 - 1 | StrugaStruga |
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| 12 Nov 22 | r15 | StrugaStruga | 1 - 0 | Shkendija 79Shkendija 79 |
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| 26 Nov 22 | r16 | SileksSileks | 1 - 2 | StrugaStruga |
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| 04 Dec 22 | r17 | StrugaStruga | 1 - 0 | Akademija PandevAkademija Pan |
| |
| 11 Dec 22 | r18 | SkopjeSkopje | 1 - 1 | StrugaStruga |
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| 19 Feb 23 | r19 | TikvešTikveš | 1 - 1 | StrugaStruga |
| |
| 25 Feb 23 | r20 | StrugaStruga | 0 - 0 | Makedonija GjPMakedonija Gj |
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| 05 Mar 23 | r21 | RenovaRenova | - | StrugaStruga |
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| 08 Mar 23 | r22 | StrugaStruga | 2 - 1 | ShkupiShkupi |
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| 12 Mar 23 | r23 | StrugaStruga | 0 - 0 | Makedonija GjPMakedonija Gj |
| |
| 18 Mar 23 | r24 | RabotnichkiRabotnichki | 0 - 1 | StrugaStruga |
| |
| 02 Apr 23 | r25 | StrugaStruga | 3 - 1 | Akademija PandevAkademija Pan |
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| 09 Apr 23 | r26 | SkopjeSkopje | 1 - 1 | StrugaStruga |
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| 15 Apr 23 | r27 | StrugaStruga | 6 - 2 | PobedaPobeda |
| |
| 26 Apr 23 | r29 | StrugaStruga | 2 - 0 | TikvešTikveš |
| |
| 30 Apr 23 | r30 | Bregalnica ŠtipBregalnica Št | 0 - 3 | StrugaStruga |
| |
| 07 May 23 | r31 | StrugaStruga | 3 - 0 | SileksSileks |
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| 10 May 23 | r32 | Shkendija 79Shkendija 79 | 1 - 2 | StrugaStruga |
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| 14 May 23 | r33 | StrugaStruga | 2 - 1 | ShkupiShkupi |
Team 2022-2023 Schedules
Arsimi
Bashkimi
Brera Strumica
Makedonija Gjorche Petrov
Pelister
Rabotnichki
Shkëndija
Shkupi
Sileks
Struga
Tikvesh
Vardar
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