| 30 Aug 20 | r01   | Almere City FCAlmere City F | 0 - 0 | MVV MaastrichtMVV Maastrich |
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| 05 Sep 20 | r02 | MVV MaastrichtMVV Maastrich | 1 - 7 | SC CambuurSC Cambuur |
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| 13 Sep 20 | r03 | SC TelstarSC Telstar | 1 - 2 | MVV MaastrichtMVV Maastrich |
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| 22 Sep 20 | r04 | FC Den BoschFC Den Bosch | 2 - 0 | MVV MaastrichtMVV Maastrich |
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| 25 Sep 20 | r05 | MVV MaastrichtMVV Maastrich | 3 - 0 | TOP OssTOP Oss |
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| 02 Oct 20 | r06  | Jong AZJong AZ | 3 - 3 | MVV MaastrichtMVV Maastrich |
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| 10 Oct 20 | r07 | MVV MaastrichtMVV Maastrich | 0 - 2 | Go Ahead EaglesGo Ahead Eagl |
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| 16 Oct 20 | r08 | ExcelsiorExcelsior | 2 - 0 | MVV MaastrichtMVV Maastrich |
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| 23 Oct 20 | r09 | MVV MaastrichtMVV Maastrich | 1 - 5 | Jong AjaxJong Ajax |
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| 30 Oct 20 | r10 | Helmond SportHelmond Sport | 1 - 1 | MVV MaastrichtMVV Maastrich |
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| 06 Nov 20 | r11 | MVV MaastrichtMVV Maastrich | 1 - 4 | NAC BredaNAC Breda |
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| 14 Nov 20 | r12 | Roda JCRoda JC | 2 - 0 | MVV MaastrichtMVV Maastrich |
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| 20 Nov 20 | r13 | MVV MaastrichtMVV Maastrich | 3 - 3 | Jong PSVJong PSV |
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| 30 Nov 20 | r14 | NEC NijmegenNEC Nijmegen | 2 - 1 | MVV MaastrichtMVV Maastrich |
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| 04 Dec 20 | r15 | MVV MaastrichtMVV Maastrich | 2 - 3 | De GraafschapDe Graafschap |
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| 12 Dec 20 | r16 | FC EindhovenFC Eindhoven | 4 - 0 | MVV MaastrichtMVV Maastrich |
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| 18 Dec 20 | r17 | MVV MaastrichtMVV Maastrich | 3 - 1 | FC DordrechtFC Dordrecht |
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| 03 Jan 21 | r18 | FC VolendamFC Volendam | 0 - 1 | MVV MaastrichtMVV Maastrich |
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| 08 Jan 21 | r19 | MVV MaastrichtMVV Maastrich | 0 - 2 | Jong UtrechtJong Utrecht |
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| 15 Jan 21 | r20 | Go Ahead EaglesGo Ahead Eagl | 3 - 0 | MVV MaastrichtMVV Maastrich |
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| 22 Jan 21 | r21 | MVV MaastrichtMVV Maastrich | 1 - 1 | Helmond SportHelmond Sport |
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| 31 Jan 21 | r22 | SC CambuurSC Cambuur | 2 - 0 | MVV MaastrichtMVV Maastrich |
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| 06 Feb 21 | r23 | MVV MaastrichtMVV Maastrich | 2 - 1 | NEC NijmegenNEC Nijmegen |
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| 13 Feb 21 | r24 | De GraafschapDe Graafschap | 1 - 0 | MVV MaastrichtMVV Maastrich |
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| 20 Feb 21 | r25 | MVV MaastrichtMVV Maastrich | 1 - 0 | ExcelsiorExcelsior |
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| 26 Feb 21 | r26 | MVV MaastrichtMVV Maastrich | 2 - 0 | SC TelstarSC Telstar |
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| 05 Mar 21 | r27 | Jong UtrechtJong Utrecht | 0 - 1 | MVV MaastrichtMVV Maastrich |
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| 12 Mar 21 | r28 | MVV MaastrichtMVV Maastrich | 3 - 2 | Jong AZJong AZ |
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| 19 Mar 21 | r29 | Jong AjaxJong Ajax | 4 - 3 | MVV MaastrichtMVV Maastrich |
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| 26 Mar 21 | r30 | MVV MaastrichtMVV Maastrich | 2 - 0 | Almere City FCAlmere City F |
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| 02 Apr 21 | r31 | MVV MaastrichtMVV Maastrich | 2 - 0 | FC EindhovenFC Eindhoven |
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| 05 Apr 21 | r32 | Jong PSVJong PSV | 3 - 1 | MVV MaastrichtMVV Maastrich |
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| 12 Apr 21 | r33 | MVV MaastrichtMVV Maastrich | 2 - 4 | Roda JCRoda JC |
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| 16 Apr 21 | r34 | TOP OssTOP Oss | 2 - 2 | MVV MaastrichtMVV Maastrich |
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| 23 Apr 21 | r35 | FC DordrechtFC Dordrecht | 0 - 1 | MVV MaastrichtMVV Maastrich |
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| 30 Apr 21 | r36 | MVV MaastrichtMVV Maastrich | 2 - 2 | FC VolendamFC Volendam |
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| 07 May 21 | r37 | NAC BredaNAC Breda | 2 - 0 | MVV MaastrichtMVV Maastrich |
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| 12 May 21 | r38 | MVV MaastrichtMVV Maastrich | 3 - 1 | FC Den BoschFC Den Bosch |
Team 2020-2021 Schedules
ADO Den Haag
Almere City
De Graafschap
FC Den Bosch
FC Dordrecht
FC Eindhoven
FC Emmen
Helmond Sport
Jong Ajax
Jong AZ
Jong PSV
Jong Utrecht
MVV Maastricht
RKC Waalwijk
Roda JC
SC Cambuur
TOP Oss
VVV-Venlo
Willem II
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