| 04 Oct 20 | r01  | HSG WetzlarHSG Wetzlar | 27 - 29 | SG Flensburg-HandewittSG Flensburg- |
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| 07 Oct 20 | r02 | GWD MindenGWD Minden | 24 - 29 | HSG WetzlarHSG Wetzlar |
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| 10 Oct 20 | r03 | HSG WetzlarHSG Wetzlar | 31 - 22 | THW KielTHW Kiel |
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| 15 Oct 20 | r04 | Bergischer HCBergischer HC | 20 - 22 | HSG WetzlarHSG Wetzlar |
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| 25 Oct 20 | r05 | HSG WetzlarHSG Wetzlar | 25 - 33 | MT MelsungenMT Melsungen |
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| 01 Nov 20 | r06 | Füchse BerlinFüchse Berlin | 35 - 28 | HSG WetzlarHSG Wetzlar |
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| 12 Nov 20 | r07 | HSG WetzlarHSG Wetzlar | 31 - 22 | HSC 2000 CoburgHSC 2000 Cobu |
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| 19 Nov 20 | r09 | HSG WetzlarHSG Wetzlar | 29 - 11 | TSG FriesenheimTSG Friesenhe |
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| 22 Nov 20 | r08 | TPSG Frisch Auf GöppingenTPSG Frisch A | 33 - 30 | HSG WetzlarHSG Wetzlar |
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| 26 Nov 20 | r10 | Rhein-Neckar LöwenRhein-Neckar | 37 - 24 | HSG WetzlarHSG Wetzlar |
| 06 Dec 20 | r10 | HSG WetzlarHSG Wetzlar | 30 - 25 | TVB 1898 StuttgartTVB 1898 Stut |
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| 10 Dec 20 | r12 | SC DHfK LeipzigSC DHfK Leipz | 32 - 28 | HSG WetzlarHSG Wetzlar |
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| 15 Dec 20 | r13 | HSG WetzlarHSG Wetzlar | 36 - 26 | HBW Balingen-WeilstettenHBW Balingen- |
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| 17 Dec 20 | r14 | TBV LemgoTBV Lemgo | 28 - 27 | HSG WetzlarHSG Wetzlar |
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| 22 Dec 20 | r15 | HSG WetzlarHSG Wetzlar | 24 - 24 | SC MagdeburgSC Magdeburg |
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| 27 Dec 20 | r16 | TUSEM EssenTUSEM Essen | 29 - 36 | HSG WetzlarHSG Wetzlar |
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| 18 Feb 21 | r19 | HSG WetzlarHSG Wetzlar | 26 - 24 | TSV Hannover-BurgdorfTSV Hannover- |
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| 25 Feb 21 | r17 | HSG WetzlarHSG Wetzlar | 28 - 28 | HC ErlangenHC Erlangen |
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| 04 Mar 21 | r20 | TSG FriesenheimTSG Friesenhe | 27 - 27 | HSG WetzlarHSG Wetzlar |
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| 17 Mar 21 | r21 | HSG WetzlarHSG Wetzlar | 31 - 32 | TPSG Frisch Auf GöppingenTPSG Frisch A |
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| 20 Mar 21 | r20 | THW KielTHW Kiel | 23 - 19 | HSG WetzlarHSG Wetzlar |
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| 25 Mar 21 | r23 | HSC 2000 CoburgHSC 2000 Cobu | 30 - 30 | HSG WetzlarHSG Wetzlar |
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| 04 Apr 21 | r24 | HSG WetzlarHSG Wetzlar | 34 - 32 | Rhein-Neckar LöwenRhein-Neckar |
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| 11 Apr 21 | r25 | TVB 1898 StuttgartTVB 1898 Stut | 24 - 31 | HSG WetzlarHSG Wetzlar |
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| 15 Apr 21 | r26 | HSG WetzlarHSG Wetzlar | 29 - 27 | Füchse BerlinFüchse Berlin |
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| 22 Apr 21 | r27 | TSV Hannover-BurgdorfTSV Hannover- | 25 - 24 | HSG WetzlarHSG Wetzlar |
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| 25 Apr 21 | r18 | HSG Nordhorn-LingenHSG Nordhorn- | 29 - 30 | HSG WetzlarHSG Wetzlar |
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| 05 May 21 | r28 | HSG WetzlarHSG Wetzlar | 21 - 27 | TBV LemgoTBV Lemgo |
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| 08 May 21 | r29 | SG Flensburg-HandewittSG Flensburg- | 32 - 24 | HSG WetzlarHSG Wetzlar |
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| 13 May 21 | r30 | HSG WetzlarHSG Wetzlar | 35 - 26 | HSG Nordhorn-LingenHSG Nordhorn- |
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| 26 May 21 | r31 | HC ErlangenHC Erlangen | 28 - 36 | HSG WetzlarHSG Wetzlar |
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| 29 May 21 | r32 | HSG WetzlarHSG Wetzlar | 30 - 22 | Bergischer HCBergischer HC |
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| 06 Jun 21 | r33 | MT MelsungenMT Melsungen | 30 - 28 | HSG WetzlarHSG Wetzlar |
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| 10 Jun 21 | r34 | HSG WetzlarHSG Wetzlar | 26 - 30 | TUSEM EssenTUSEM Essen |
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| 16 Jun 21 | r35 | HBW Balingen-WeilstettenHBW Balingen- | 30 - 28 | HSG WetzlarHSG Wetzlar |
| |
| 19 Jun 21 | r36 | HSG WetzlarHSG Wetzlar | 29 - 26 | SC DHfK LeipzigSC DHfK Leipz |
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| 24 Jun 21 | r37 | SC MagdeburgSC Magdeburg | 27 - 27 | HSG WetzlarHSG Wetzlar |
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| 27 Jun 21 | r38 | HSG WetzlarHSG Wetzlar | 28 - 25 | GWD MindenGWD Minden |
Team 2020-2021 Schedules
Bergischer HC
Füchse Berlin
GWD Minden
Handball Sport Verein Hamburg
HC Erlangen
HSG Wetzlar
MT Melsungen
Rhein-Neckar Löwen
SC DHfK Leipzig
SC Magdeburg
SG Flensburg-Handewitt
TBV Lemgo
ThSV Eisenach
THW Kiel
TPSG Frisch Auf Göppingen
TSV Hannover-Burgdorf
TVB 1898 Stuttgart
VfL Gummersbach
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