| 06 Nov 19 | r09  | GuimaraesGuimaraes | 1 - 1 | ArsenalArsenal |
| 07 Nov 19 | r09  | FC AstanaFC Astana | 0 - 5 | AZ AlkmaarAZ Alkmaar |
| 07 Nov 19 | r09 | LazioLazio | 1 - 2 | CelticCeltic |
| 07 Nov 19 | r09 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 0 | RennesRennes |
| 07 Nov 19 | r09 | StandardStandard | 2 - 1 | Ein FrankfurtEin Frankfurt |
| 07 Nov 19 | r09 | Apoel NicosiaApoel Nicosia | 2 - 1 | Qarabag FKQarabag FK |
| 07 Nov 19 | r09 | F91 DudelangeF91 Dudelange | 2 - 5 | SevillaSevilla |
| 07 Nov 19 | r09 | FC CopenhagenFC Copenhagen | 1 - 1 | Dynamo KievDynamo Kiev |
| 07 Nov 19 | r09 | LuganoLugano | 0 - 0 | Malmo FFMalmo FF |
| 07 Nov 19 | r09 | FC BaselFC Basel | 2 - 1 | GetafeGetafe |
| 07 Nov 19 | r09 | Kuban KrasnodarKuban Krasnod | 3 - 1 | TrabzonsporTrabzonspor |
| 07 Nov 19 | r09 | RosenborgRosenborg | 0 - 2 | Sporting CPSporting CP |
| 07 Nov 19 | r09 | LASKLASK | 4 - 1 | PSV EindhovenPSV Eindhoven |
| 07 Nov 19 | r09 | FeyenoordFeyenoord | 1 - 1 | Young BoysYoung Boys |
| 07 Nov 19 | r09 | RangersRangers | 2 - 0 | FC PortoFC Porto |
| 07 Nov 19 | r09 | WolfsburgWolfsburg | 1 - 3 | GentGent |
| 07 Nov 19 | r09 | AlessandriaAlessandria | 2 - 2 | St EtienneSt Etienne |
| 07 Nov 19 | r09 | EspanolEspanol | 6 - 0 | Ludogorets Razgrad Ludogorets Ra |
| 07 Nov 19 | r09 | FerencvarosFerencvaros | 0 - 0 | CSKA MoscowCSKA Moscow |
| 07 Nov 19 | r09 | M'gladbachM'gladbach | 2 - 1 | RomaRoma |
| 07 Nov 19 | r09 | Wolfsberger ACWolfsberger A | 0 - 3 | Istanbul BasaksehirIstanbul Basa |
| 07 Nov 19 | r09 | BragaBraga | 3 - 1 | BesiktasBesiktas |
| 07 Nov 19 | r09 | WolvesWolves | 1 - 0 | Slovan Bratislava Slovan Bratis |
| 07 Nov 19 | r09 | Manchester UnitedManchester Un | 3 - 0 | Partizan BelgradePartizan Belg |
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