| 20 Feb 20 | r12  | Sporting CPSporting CP | 3 - 1 | Istanbul BasaksehirIstanbul Basa |
| 20 Feb 20 | r12 | GetafeGetafe | 2 - 0 | AjaxAjax |
| 20 Feb 20 | r12 | FC CopenhagenFC Copenhagen | 1 - 1 | CelticCeltic |
| 20 Feb 20 | r12 | CFR Cluj-NapocaCFR Cluj-Napo | 1 - 1 | SevillaSevilla |
| 20 Feb 20 | r12 | Club BruggeClub Brugge | 1 - 1 | Manchester UnitedManchester Un |
| 20 Feb 20 | r12 | Ludogorets Razgrad Ludogorets Ra | 0 - 2 | InterInter |
| 20 Feb 20 | r12 | Ein FrankfurtEin Frankfurt | 4 - 1 | SV SalzburgSV Salzburg |
| 20 Feb 20 | r12 | Shakhtar DonetskShakhtar Done | 2 - 1 | BenficaBenfica |
| 20 Feb 20 | r12 | WolvesWolves | 4 - 0 | EspanolEspanol |
| 20 Feb 20 | r12 | LeverkusenLeverkusen | 2 - 1 | FC PortoFC Porto |
| 20 Feb 20 | r12 | Apoel NicosiaApoel Nicosia | 0 - 3 | FC BaselFC Basel |
| 20 Feb 20 | r12 | OlympiakosOlympiakos | 0 - 1 | ArsenalArsenal |
| 20 Feb 20 | r12 | AZ AlkmaarAZ Alkmaar | 1 - 1 | LASKLASK |
| 20 Feb 20 | r12 | WolfsburgWolfsburg | 2 - 1 | Malmo FFMalmo FF |
| 20 Feb 20 | r12 | RomaRoma | 1 - 0 | GentGent |
| 20 Feb 20 | r12 | RangersRangers | 3 - 2 | BragaBraga |
| 26 Feb 20 | r12  | BragaBraga | 0 - 1 | RangersRangers |
| 27 Feb 20 | r12 | EspanolEspanol | 3 - 2 | WolvesWolves |
| 27 Feb 20 | r12 | Istanbul BasaksehirIstanbul Basa | 4 - 1 | Sporting CPSporting CP |
| 27 Feb 20 | r12 | FC PortoFC Porto | 1 - 3 | LeverkusenLeverkusen |
| 27 Feb 20 | r12 | FC BaselFC Basel | 1 - 0 | Apoel NicosiaApoel Nicosia |
| 27 Feb 20 | r12 | LASKLASK | 2 - 0 | AZ AlkmaarAZ Alkmaar |
| 27 Feb 20 | r12 | Malmo FFMalmo FF | 0 - 3 | WolfsburgWolfsburg |
| 27 Feb 20 | r12 | GentGent | 1 - 1 | RomaRoma |
| 27 Feb 20 | r12 | AjaxAjax | 2 - 1 | GetafeGetafe |
| 27 Feb 20 | r12 | CelticCeltic | 1 - 3 | FC CopenhagenFC Copenhagen |
| 27 Feb 20 | r12 | SevillaSevilla | 0 - 0 | CFR Cluj-NapocaCFR Cluj-Napo |
| 27 Feb 20 | r12 | ArsenalArsenal | 1 - 2 | OlympiakosOlympiakos |
| 27 Feb 20 | r12 | Manchester UnitedManchester Un | 5 - 0 | Club BruggeClub Brugge |
| 27 Feb 20 | r12 | InterInter | 2 - 1 | Ludogorets Razgrad Ludogorets Ra |
| 27 Feb 20 | r12 | BenficaBenfica | 3 - 3 | Shakhtar DonetskShakhtar Done |
| 28 Feb 20 | r12 | SV SalzburgSV Salzburg | 2 - 2 | Ein FrankfurtEin Frankfurt |
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