| 12 Dec 19 | r11  | Qarabag FKQarabag FK | 1 - 1 | F91 DudelangeF91 Dudelange |
| 12 Dec 19 | r11 | Apoel NicosiaApoel Nicosia | 1 - 0 | SevillaSevilla |
| 12 Dec 19 | r11 | Dynamo KievDynamo Kiev | 1 - 1 | LuganoLugano |
| 12 Dec 19 | r11 | FC CopenhagenFC Copenhagen | 0 - 1 | Malmo FFMalmo FF |
| 12 Dec 19 | r11 | GetafeGetafe | 3 - 0 | FC KrasnodarFC Krasnodar |
| 12 Dec 19 | r11 | FC BaselFC Basel | 2 - 0 | TrabzonsporTrabzonspor |
| 12 Dec 19 | r11 | LASKLASK | 3 - 0 | Sporting CPSporting CP |
| 12 Dec 19 | r11 | PSV EindhovenPSV Eindhoven | 1 - 1 | RosenborgRosenborg |
| 12 Dec 19 | r11 | CFR Cluj-NapocaCFR Cluj-Napo | 2 - 0 | CelticCeltic |
| 12 Dec 19 | r11 | Ein FrankfurtEin Frankfurt | 2 - 3 | GuimaraesGuimaraes |
| 12 Dec 19 | r11 | StandardStandard | 2 - 2 | ArsenalArsenal |
| 12 Dec 19 | r11 | FC PortoFC Porto | 3 - 2 | FeyenoordFeyenoord |
| 12 Dec 19 | r11 | RangersRangers | 1 - 1 | Young BoysYoung Boys |
| 12 Dec 19 | r11 | Ludogorets Razgrad Ludogorets Ra | 1 - 1 | FerencvarosFerencvaros |
| 12 Dec 19 | r11 | EspanolEspanol | 0 - 1 | CSKA MoscowCSKA Moscow |
| 12 Dec 19 | r11 | GentGent | 2 - 1 | FC OlexandriaFC Olexandria |
| 12 Dec 19 | r11 | WolfsburgWolfsburg | 1 - 0 | St EtienneSt Etienne |
| 12 Dec 19 | r11 | RomaRoma | 2 - 2 | Wolfsberger ACWolfsberger A |
| 12 Dec 19 | r11 | M'gladbachM'gladbach | 1 - 2 | Istanbul BasaksehirIstanbul Basa |
| 12 Dec 19 | r11 | Slovan Bratislava Slovan Bratis | 2 - 4 | BragaBraga |
| 12 Dec 19 | r11 | WolvesWolves | 4 - 0 | BesiktasBesiktas |
| 12 Dec 19 | r11 | Manchester UnitedManchester Un | 4 - 0 | AZ AlkmaarAZ Alkmaar |
| 12 Dec 19 | r11 | Partizan BelgradePartizan Belg | 4 - 1 | FC AstanaFC Astana |
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