| 24 Oct 19 | r08  | Qarabag FKQarabag FK | 2 - 2 | Apoel NicosiaApoel Nicosia |
| 24 Oct 19 | r08   | FC PortoFC Porto | 1 - 1 | RangersRangers |
| 24 Oct 19 | r08 | Young BoysYoung Boys | 2 - 0 | FeyenoordFeyenoord |
| 24 Oct 19 | r08 | GentGent | 2 - 2 | WolfsburgWolfsburg |
| 24 Oct 19 | r08 | St EtienneSt Etienne | 1 - 1 | AlessandriaAlessandria |
| 24 Oct 19 | r08 | CSKA MoscowCSKA Moscow | 0 - 1 | FerencvarosFerencvaros |
| 24 Oct 19 | r08 | Ludogorets Razgrad Ludogorets Ra | 0 - 1 | EspanolEspanol |
| 24 Oct 19 | r08 | RomaRoma | 1 - 1 | M'gladbachM'gladbach |
| 24 Oct 19 | r08 | Istanbul BasaksehirIstanbul Basa | 1 - 0 | Wolfsberger ACWolfsberger A |
| 24 Oct 19 | r08 | Partizan BelgradePartizan Belg | 0 - 1 | Manchester UnitedManchester Un |
| 24 Oct 19 | r08 | Slovan Bratislava Slovan Bratis | 1 - 2 | WolvesWolves |
| 24 Oct 19 | r08 | ArsenalArsenal | 3 - 2 | GuimaraesGuimaraes |
| 24 Oct 19 | r08 | CelticCeltic | 2 - 1 | LazioLazio |
| 24 Oct 19 | r08 | RennesRennes | 0 - 1 | CFR Cluj-NapocaCFR Cluj-Napo |
| 24 Oct 19 | r08 | Ein FrankfurtEin Frankfurt | 2 - 1 | StandardStandard |
| 24 Oct 19 | r08 | SevillaSevilla | 3 - 0 | F91 DudelangeF91 Dudelange |
| 24 Oct 19 | r08 | Dynamo KievDynamo Kiev | 1 - 1 | FC CopenhagenFC Copenhagen |
| 24 Oct 19 | r08 | Malmo FFMalmo FF | 2 - 1 | LuganoLugano |
| 24 Oct 19 | r08 | GetafeGetafe | 0 - 1 | FC BaselFC Basel |
| 24 Oct 19 | r08 | TrabzonsporTrabzonspor | 0 - 2 | Kuban KrasnodarKuban Krasnod |
| 24 Oct 19 | r08 | Sporting CPSporting CP | 1 - 0 | RosenborgRosenborg |
| 24 Oct 19 | r08 | PSV EindhovenPSV Eindhoven | 0 - 0 | LASKLASK |
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