| 10 Oct 21 | r01        | Hapoel Beer Sheva BCHapoel Beer S | 83 - 69 | Hapoel Gilboa GalilHapoel Gilboa |
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| 17 Oct 21 | r02        | Hapoel Gilboa GalilHapoel Gilboa | 87 - 83 | Maccabi Tel Aviv BCMaccabi Tel A |
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| 24 Oct 21 | r03        | Hapoel HolonHapoel Holon | 84 - 82 | Hapoel Gilboa GalilHapoel Gilboa |
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| 31 Oct 21 | r04        | Hapoel Gilboa GalilHapoel Gilboa | 94 - 86 | Hapoel Eilat BCHapoel Eilat |
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| 07 Nov 21 | r05        | Hapoel Jerusalem BCHapoel Jerusa | 80 - 68 | Hapoel Gilboa GalilHapoel Gilboa |
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| 14 Nov 21 | r06        | Hapoel Galil ElyonHapoel Galil | 74 - 85 | Hapoel Gilboa GalilHapoel Gilboa |
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| 21 Nov 21 | r07        | Hapoel Gilboa GalilHapoel Gilboa | 78 - 89 | Ironi Nes Ziona BCIroni Nes Zio |
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| 06 Dec 21 | r08        | Maccabi Rishon LeZionMaccabi Risho | 94 - 100 | Hapoel Gilboa GalilHapoel Gilboa |
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| 12 Dec 21 | r09        | Hapoel Gilboa GalilHapoel Gilboa | 71 - 80 | Hapoel Haifa BCHapoel Haifa |
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| 20 Dec 21 | r10        | Hapoel Tel Aviv BCHapoel Tel Av | 89 - 68 | Hapoel Gilboa GalilHapoel Gilboa |
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| 27 Dec 21 | r11        | Hapoel Gilboa GalilHapoel Gilboa | 82 - 94 | Bnei Herzliya BasketBnei Herzliya |
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| 02 Jan 22 | r13        | Hapoel Gilboa GalilHapoel Gilboa | 73 - 87 | Hapoel Tel Aviv BCHapoel Tel Av |
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| 08 Jan 22 | r14        | Hapoel Gilboa GalilHapoel Gilboa | 78 - 72 | Hapoel Jerusalem BCHapoel Jerusa |
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| 20 Jan 22 | r12        | Hapoel Haifa BCHapoel Haifa | 72 - 68 | Hapoel Gilboa GalilHapoel Gilboa |
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| 24 Jan 22 | r15        | Bnei Herzliya BasketBnei Herzliya | 80 - 71 | Hapoel Gilboa GalilHapoel Gilboa |
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| 03 Feb 22 | r16        | Hapoel Gilboa GalilHapoel Gilboa | 71 - 62 | Hapoel Galil ElyonHapoel Galil |
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| 19 Feb 22 | r18        | Hapoel Gilboa GalilHapoel Gilboa | 74 - 81 | Hapoel HolonHapoel Holon |
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| 07 Mar 22 | r19        | Hapoel Gilboa GalilHapoel Gilboa | 72 - 60 | Hapoel Beer Sheva BCHapoel Beer S |
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| 14 Mar 22 | r20        | Hapoel Eilat BCHapoel Eilat | 94 - 97 | Hapoel Gilboa GalilHapoel Gilboa |
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| 21 Mar 22 | r21        | Hapoel Gilboa GalilHapoel Gilboa | 96 - 88 | Maccabi Rishon LeZionMaccabi Risho |
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| 25 Mar 22 | r22        | Ironi Nes Ziona BCIroni Nes Zio | 81 - 71 | Hapoel Gilboa GalilHapoel Gilboa |
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| 04 Apr 22 | r17        | Maccabi Tel Aviv BCMaccabi Tel A | 84 - 61 | Hapoel Gilboa GalilHapoel Gilboa |
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| 11 Apr 22 | r23        | Hapoel Gilboa GalilHapoel Gilboa | 91 - 81 | Hapoel Eilat BCHapoel Eilat |
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| 18 Apr 22 | r24        | Maccabi Rishon LeZionMaccabi Risho | 79 - 85 | Hapoel Gilboa GalilHapoel Gilboa |
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| 24 Apr 22 | r25        | Hapoel Gilboa GalilHapoel Gilboa | 84 - 75 | Hapoel Tel Aviv BCHapoel Tel Av |
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| 02 May 22 | r26        | Hapoel Gilboa GalilHapoel Gilboa | 102 - 89 | Hapoel Beer Sheva BCHapoel Beer S |
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| 08 May 22 | r27        | Ironi Nes Ziona BCIroni Nes Zio | 93 - 73 | Hapoel Gilboa GalilHapoel Gilboa |
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| 12 May 22 | r00        | Hapoel Jerusalem BCHapoel Jerusa | 85 - 88 | Hapoel Gilboa GalilHapoel Gilboa |
| 17 May 22 | r00        | Hapoel Gilboa GalilHapoel Gilboa | 61 - 96 | Hapoel Jerusalem BCHapoel Jerusa |
| 20 May 22 | r00        | Hapoel Jerusalem BCHapoel Jerusa | 87 - 60 | Hapoel Gilboa GalilHapoel Gilboa |
| 23 May 22 | r00        | Hapoel Gilboa GalilHapoel Gilboa | 42 - 84 | Hapoel Jerusalem BCHapoel Jerusa |