| 04 Apr 00 | r00  | Pittsburgh PiratesPittsburgh Pi | 2 - 11 | Houston AstrosHouston Astro |
| 05 Apr 00 | r00 | Pittsburgh PiratesPittsburgh Pi | 10 - 1 | Houston AstrosHouston Astro |
| 06 Apr 00 | r00 | Houston AstrosHouston Astro | 1 - 4 | Philadelphia PhilliesPhiladelphia |
| 07 Apr 00 | r00 | Houston AstrosHouston Astro | 8 - 5 | Philadelphia PhilliesPhiladelphia |
| 08 Apr 00 | r00 | Houston AstrosHouston Astro | 2 - 3 | Philadelphia PhilliesPhiladelphia |
| 09 Apr 00 | r00  | Houston AstrosHouston Astro | 7 - 8 | St. Louis CardinalsSt. Louis Car |
| 10 Apr 00 | r00 | Houston AstrosHouston Astro | 6 - 10 | St. Louis CardinalsSt. Louis Car |
| 11 Apr 00 | r00 | Houston AstrosHouston Astro | 7 - 5 | St. Louis CardinalsSt. Louis Car |
| 13 Apr 00 | r00 | San Diego PadresSan Diego Pad | 4 - 10 | Houston AstrosHouston Astro |
| 14 Apr 00 | r00 | San Diego PadresSan Diego Pad | 5 - 3 | Houston AstrosHouston Astro |
| 15 Apr 00 | r00 | San Diego PadresSan Diego Pad | 13 - 3 | Houston AstrosHouston Astro |
| 17 Apr 00 | r00 | Los Angeles DodgersLos Angeles D | 5 - 3 | Houston AstrosHouston Astro |
| 18 Apr 00 | r00 | Los Angeles DodgersLos Angeles D | 3 - 10 | Houston AstrosHouston Astro |
| 20 Apr 00 | r00 | Houston AstrosHouston Astro | 2 - 7 | San Diego PadresSan Diego Pad |
| 21 Apr 00 | r00 | Houston AstrosHouston Astro | 6 - 8 | San Diego PadresSan Diego Pad |
| 22 Apr 00 | r00 | Houston AstrosHouston Astro | 10 - 11 | San Diego PadresSan Diego Pad |
| 24 Apr 00 | r00 | Houston AstrosHouston Astro | 11 - 7 | Chicago CubsChicago Cubs |
| 25 Apr 00 | r00 | Houston AstrosHouston Astro | 8 - 13 | Chicago CubsChicago Cubs |
| 26 Apr 00 | r00 | Houston AstrosHouston Astro | 3 - 12 | Chicago CubsChicago Cubs |
| 27 Apr 00 | r00 | Milwaukee BrewersMilwaukee Bre | 0 - 7 | Houston AstrosHouston Astro |
| 28 Apr 00 | r00 | Milwaukee BrewersMilwaukee Bre | 3 - 10 | Houston AstrosHouston Astro |
| 29 Apr 00 | r00 | Milwaukee BrewersMilwaukee Bre | 4 - 3 | Houston AstrosHouston Astro |
| 30 Apr 00 | r00 | Milwaukee BrewersMilwaukee Bre | 0 - 5 | Houston AstrosHouston Astro |
| 01 May 00 | r00 | Chicago CubsChicago Cubs | 11 - 1 | Houston AstrosHouston Astro |
| 02 May 00 | r00 | Chicago CubsChicago Cubs | 4 - 3 | Houston AstrosHouston Astro |
| 03 May 00 | r00 | Chicago CubsChicago Cubs | 2 - 6 | Houston AstrosHouston Astro |
| 04 May 00 | r00 | Los Angeles DodgersLos Angeles D | 3 - 2 | Houston AstrosHouston Astro |
| 05 May 00 | r00 | Los Angeles DodgersLos Angeles D | 9 - 6 | Houston AstrosHouston Astro |
| 06 May 00 | r00 | Los Angeles DodgersLos Angeles D | 8 - 14 | Houston AstrosHouston Astro |
| 07 May 00 | r00 | Houston AstrosHouston Astro | 1 - 3 | Colorado RockiesColorado Rock |
| 08 May 00 | r00 | Houston AstrosHouston Astro | 13 - 8 | Colorado RockiesColorado Rock |
| 09 May 00 | r00 | Houston AstrosHouston Astro | 5 - 1 | Colorado RockiesColorado Rock |
| 11 May 00 | r00 | Houston AstrosHouston Astro | 3 - 7 | Cincinnati RedsCincinnati Re |
| 12 May 00 | r00 | Houston AstrosHouston Astro | 7 - 8 | Cincinnati RedsCincinnati Re |
| 13 May 00 | r00 | Houston AstrosHouston Astro | 10 - 3 | Cincinnati RedsCincinnati Re |
| 14 May 00 | r00 | Houston AstrosHouston Astro | 3 - 4 | Cincinnati RedsCincinnati Re |
| 15 May 00 | r00 | Milwaukee BrewersMilwaukee Bre | 6 - 5 | Houston AstrosHouston Astro |
| 18 May 00 | r00 | Washington NationalsWashington Na | 3 - 2 | Houston AstrosHouston Astro |
| 19 May 00 | r00 | Washington NationalsWashington Na | 8 - 7 | Houston AstrosHouston Astro |
| 20 May 00 | r00 | Washington NationalsWashington Na | 8 - 3 | Houston AstrosHouston Astro |
| 21 May 00 | r00 | Milwaukee BrewersMilwaukee Bre | 10 - 9 | Houston AstrosHouston Astro |
| 22 May 00 | r00 | Houston AstrosHouston Astro | 10 - 2 | Philadelphia PhilliesPhiladelphia |
| 23 May 00 | r00 | Houston AstrosHouston Astro | 7 - 9 | Philadelphia PhilliesPhiladelphia |
| 24 May 00 | r00 | Houston AstrosHouston Astro | 10 - 6 | Philadelphia PhilliesPhiladelphia |
| 25 May 00 | r00 | Houston AstrosHouston Astro | 5 - 4 | Atlanta BravesAtlanta Brave |
| 26 May 00 | r00 | Houston AstrosHouston Astro | 5 - 6 | Atlanta BravesAtlanta Brave |
| 27 May 00 | r00 | Houston AstrosHouston Astro | 4 - 3 | Atlanta BravesAtlanta Brave |
| 28 May 00 | r00 | Colorado RockiesColorado Rock | 8 - 7 | Houston AstrosHouston Astro |
| 29 May 00 | r00 | Colorado RockiesColorado Rock | 10 - 7 | Houston AstrosHouston Astro |
| 30 May 00 | r00 | Colorado RockiesColorado Rock | 8 - 6 | Houston AstrosHouston Astro |
| 01 Jun 00 | r00 | Houston AstrosHouston Astro | 4 - 7 | Chicago White SoxChicago White |
| 02 Jun 00 | r00 | Houston AstrosHouston Astro | 6 - 1 | Chicago White SoxChicago White |
| 03 Jun 00 | r00 | Houston AstrosHouston Astro | 3 - 7 | Chicago White SoxChicago White |
| 04 Jun 00 | r00 | Houston AstrosHouston Astro | 8 - 2 | Minnesota TwinsMinnesota Twi |
| 05 Jun 00 | r00 | Houston AstrosHouston Astro | 1 - 3 | Minnesota TwinsMinnesota Twi |
| 06 Jun 00 | r00 | Houston AstrosHouston Astro | 0 - 2 | Minnesota TwinsMinnesota Twi |
| 07 Jun 00 | r00 | Los Angeles DodgersLos Angeles D | 5 - 2 | Houston AstrosHouston Astro |
| 08 Jun 00 | r00 | San Diego PadresSan Diego Pad | 6 - 7 | Houston AstrosHouston Astro |
| 09 Jun 00 | r00 | San Diego PadresSan Diego Pad | 13 - 3 | Houston AstrosHouston Astro |
| 10 Jun 00 | r00 | San Diego PadresSan Diego Pad | 4 - 1 | Houston AstrosHouston Astro |
| 12 Jun 00 | r00 | Colorado RockiesColorado Rock | 3 - 6 | Houston AstrosHouston Astro |
| 13 Jun 00 | r00 | Colorado RockiesColorado Rock | 4 - 8 | Houston AstrosHouston Astro |
| 14 Jun 00 | r00 | Colorado RockiesColorado Rock | 5 - 4 | Houston AstrosHouston Astro |
| 15 Jun 00 | r00 | San Francisco GiantsSan Francisco | 7 - 4 | Houston AstrosHouston Astro |
| 16 Jun 00 | r00 | San Francisco GiantsSan Francisco | 6 - 4 | Houston AstrosHouston Astro |
| 17 Jun 00 | r00 | San Francisco GiantsSan Francisco | 2 - 4 | Houston AstrosHouston Astro |
| 19 Jun 00 | r00 | Houston AstrosHouston Astro | 6 - 9 | Los Angeles DodgersLos Angeles D |
| 20 Jun 00 | r00 | Houston AstrosHouston Astro | 6 - 7 | Los Angeles DodgersLos Angeles D |
| 21 Jun 00 | r00 | Houston AstrosHouston Astro | 6 - 3 | Los Angeles DodgersLos Angeles D |
| 22 Jun 00 | r00 | Houston AstrosHouston Astro | 3 - 10 | San Francisco GiantsSan Francisco |
| 23 Jun 00 | r00 | Houston AstrosHouston Astro | 4 - 13 | San Francisco GiantsSan Francisco |
| 24 Jun 00 | r00 | Houston AstrosHouston Astro | 2 - 4 | San Francisco GiantsSan Francisco |
| 25 Jun 00 | r00 | Arizona DiamondbacksArizona Diamo | 6 - 1 | Houston AstrosHouston Astro |
| 26 Jun 00 | r00 | Arizona DiamondbacksArizona Diamo | 4 - 12 | Houston AstrosHouston Astro |
| 27 Jun 00 | r00 | Arizona DiamondbacksArizona Diamo | 6 - 2 | Houston AstrosHouston Astro |
| 28 Jun 00 | r00 | Arizona DiamondbacksArizona Diamo | 7 - 1 | Houston AstrosHouston Astro |
| 29 Jun 00 | r00 | St. Louis CardinalsSt. Louis Car | 5 - 4 | Houston AstrosHouston Astro |
| 30 Jun 00 | r00 | St. Louis CardinalsSt. Louis Car | 10 - 9 | Houston AstrosHouston Astro |
| 01 Jul 00 | r00 | St. Louis CardinalsSt. Louis Car | 3 - 6 | Houston AstrosHouston Astro |
| 03 Jul 00 | r00 | Houston AstrosHouston Astro | 4 - 10 | Arizona DiamondbacksArizona Diamo |
| 04 Jul 00 | r00 | Houston AstrosHouston Astro | 9 - 12 | Arizona DiamondbacksArizona Diamo |
| 05 Jul 00 | r00 | Houston AstrosHouston Astro | 1 - 2 | Arizona DiamondbacksArizona Diamo |
| 06 Jul 00 | r00 | Houston AstrosHouston Astro | 9 - 5 | Kansas City RoyalsKansas City R |
| 07 Jul 00 | r00 | Houston AstrosHouston Astro | 2 - 5 | Kansas City RoyalsKansas City R |
| 08 Jul 00 | r00 | Houston AstrosHouston Astro | 9 - 6 | Kansas City RoyalsKansas City R |
| 12 Jul 00 | r00 | Detroit TigersDetroit Tiger | 8 - 2 | Houston AstrosHouston Astro |
| 13 Jul 00 | r00 | Detroit TigersDetroit Tiger | 4 - 9 | Houston AstrosHouston Astro |
| 14 Jul 00 | r00 | Detroit TigersDetroit Tiger | 11 - 6 | Houston AstrosHouston Astro |
| 15 Jul 00 | r00 | Cleveland IndiansCleveland Ind | 1 - 5 | Houston AstrosHouston Astro |
| 16 Jul 00 | r00 | Cleveland IndiansCleveland Ind | 8 - 6 | Houston AstrosHouston Astro |
| 17 Jul 00 | r00 | Cleveland IndiansCleveland Ind | 8 - 2 | Houston AstrosHouston Astro |
| 18 Jul 00 | r00 | Houston AstrosHouston Astro | 0 - 4 | Cincinnati RedsCincinnati Re |
| 19 Jul 00 | r00 | Houston AstrosHouston Astro | 6 - 2 | Cincinnati RedsCincinnati Re |
| 20 Jul 00 | r00 | Houston AstrosHouston Astro | 1 - 12 | St. Louis CardinalsSt. Louis Car |
| 21 Jul 00 | r00 | Houston AstrosHouston Astro | 10 - 5 | St. Louis CardinalsSt. Louis Car |
| 22 Jul 00 | r00 | Houston AstrosHouston Astro | 15 - 7 | St. Louis CardinalsSt. Louis Car |
| 23 Jul 00 | r00 | Cincinnati RedsCincinnati Re | 5 - 7 | Houston AstrosHouston Astro |
| 24 Jul 00 | r00 | Cincinnati RedsCincinnati Re | 4 - 7 | Houston AstrosHouston Astro |
| 25 Jul 00 | r00 | Cincinnati RedsCincinnati Re | 2 - 3 | Houston AstrosHouston Astro |
| 27 Jul 00 | r00 | Atlanta BravesAtlanta Brave | 5 - 2 | Houston AstrosHouston Astro |
| 28 Jul 00 | r00 | Atlanta BravesAtlanta Brave | 13 - 5 | Houston AstrosHouston Astro |
| 29 Jul 00 | r00 | Atlanta BravesAtlanta Brave | 6 - 3 | Houston AstrosHouston Astro |
| 30 Jul 00 | r00 | Miami MarlinsMiami Marlins | 2 - 4 | Houston AstrosHouston Astro |
| 31 Jul 00 | r00 | Miami MarlinsMiami Marlins | 3 - 4 | Houston AstrosHouston Astro |
| 01 Aug 00 | r00 | Miami MarlinsMiami Marlins | 5 - 4 | Houston AstrosHouston Astro |
| 02 Aug 00 | r00 | Miami MarlinsMiami Marlins | 4 - 3 | Houston AstrosHouston Astro |
| 03 Aug 00 | r00 | Houston AstrosHouston Astro | 7 - 6 | Washington NationalsWashington Na |
| 04 Aug 00 | r00 | Houston AstrosHouston Astro | 9 - 10 | Washington NationalsWashington Na |
| 05 Aug 00 | r00 | Houston AstrosHouston Astro | 8 - 1 | Washington NationalsWashington Na |
| 06 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 6 | New York MetsNew York Mets |
| 07 Aug 00 | r00 | Houston AstrosHouston Astro | 9 - 3 | New York MetsNew York Mets |
| 08 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 12 | New York MetsNew York Mets |
| 09 Aug 00 | r00 | Houston AstrosHouston Astro | 3 - 10 | New York MetsNew York Mets |
| 10 Aug 00 | r00 | Philadelphia PhilliesPhiladelphia | 2 - 7 | Houston AstrosHouston Astro |
| 11 Aug 00 | r00 | Philadelphia PhilliesPhiladelphia | 3 - 2 | Houston AstrosHouston Astro |
| 12 Aug 00 | r00 | Philadelphia PhilliesPhiladelphia | 7 - 14 | Houston AstrosHouston Astro |
| 13 Aug 00 | r00 | Houston AstrosHouston Astro | 16 - 2 | Pittsburgh PiratesPittsburgh Pi |
| 14 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 4 | Pittsburgh PiratesPittsburgh Pi |
| 15 Aug 00 | r00 | Houston AstrosHouston Astro | 11 - 10 | Pittsburgh PiratesPittsburgh Pi |
| 17 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 4 | Milwaukee BrewersMilwaukee Bre |
| 18 Aug 00 | r00 | Houston AstrosHouston Astro | 10 - 8 | Milwaukee BrewersMilwaukee Bre |
| 19 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 6 | Milwaukee BrewersMilwaukee Bre |
| 20 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 4 | Chicago CubsChicago Cubs |
| 21 Aug 00 | r00 | Houston AstrosHouston Astro | 10 - 7 | Chicago CubsChicago Cubs |
| 22 Aug 00 | r00 | Houston AstrosHouston Astro | 5 - 15 | Chicago CubsChicago Cubs |
| 24 Aug 00 | r00 | Washington NationalsWashington Na | 1 - 3 | Houston AstrosHouston Astro |
| 25 Aug 00 | r00 | Washington NationalsWashington Na | 5 - 4 | Houston AstrosHouston Astro |
| 26 Aug 00 | r00 | Washington NationalsWashington Na | 3 - 7 | Houston AstrosHouston Astro |
| 27 Aug 00 | r00 | New York MetsNew York Mets | 4 - 2 | Houston AstrosHouston Astro |
| 28 Aug 00 | r00 | New York MetsNew York Mets | 1 - 11 | Houston AstrosHouston Astro |
| 29 Aug 00 | r00 | New York MetsNew York Mets | 1 - 0 | Houston AstrosHouston Astro |
| 31 Aug 00 | r00 | Houston AstrosHouston Astro | 3 - 2 | Atlanta BravesAtlanta Brave |
| 01 Sep 00 | r00 | Houston AstrosHouston Astro | 6 - 8 | Atlanta BravesAtlanta Brave |
| 02 Sep 00 | r00 | Houston AstrosHouston Astro | 9 - 3 | Atlanta BravesAtlanta Brave |
| 03 Sep 00 | r00 | Houston AstrosHouston Astro | 2 - 5 | Miami MarlinsMiami Marlins |
| 04 Sep 00 | r00 | Houston AstrosHouston Astro | 9 - 5 | Miami MarlinsMiami Marlins |
| 05 Sep 00 | r00 | Houston AstrosHouston Astro | 13 - 5 | Miami MarlinsMiami Marlins |
| 06 Sep 00 | r00 | Houston AstrosHouston Astro | 7 - 3 | Miami MarlinsMiami Marlins |
| 07 Sep 00 | r00 | Chicago CubsChicago Cubs | 10 - 13 | Houston AstrosHouston Astro |
| 08 Sep 00 | r00 | Chicago CubsChicago Cubs | 4 - 14 | Houston AstrosHouston Astro |
| 09 Sep 00 | r00 | Chicago CubsChicago Cubs | 6 - 7 | Houston AstrosHouston Astro |
| 10 Sep 00 | r00 | Houston AstrosHouston Astro | 7 - 8 | San Francisco GiantsSan Francisco |
| 11 Sep 00 | r00 | Houston AstrosHouston Astro | 5 - 9 | San Francisco GiantsSan Francisco |
| 12 Sep 00 | r00 | Houston AstrosHouston Astro | 2 - 3 | San Francisco GiantsSan Francisco |
| 13 Sep 00 | r00 | Houston AstrosHouston Astro | 8 - 7 | Pittsburgh PiratesPittsburgh Pi |
| 14 Sep 00 | r00 | Houston AstrosHouston Astro | 16 - 7 | Pittsburgh PiratesPittsburgh Pi |
| 15 Sep 00 | r00 | Houston AstrosHouston Astro | 10 - 9 | Pittsburgh PiratesPittsburgh Pi |
| 16 Sep 00 | r00 | Houston AstrosHouston Astro | 5 - 3 | Pittsburgh PiratesPittsburgh Pi |
| 18 Sep 00 | r00 | St. Louis CardinalsSt. Louis Car | 6 - 8 | Houston AstrosHouston Astro |
| 19 Sep 00 | r00 | St. Louis CardinalsSt. Louis Car | 11 - 6 | Houston AstrosHouston Astro |
| 20 Sep 00 | r00 | St. Louis CardinalsSt. Louis Car | 5 - 7 | Houston AstrosHouston Astro |
| 21 Sep 00 | r00 | Cincinnati RedsCincinnati Re | 12 - 5 | Houston AstrosHouston Astro |
| 22 Sep 00 | r00 | Cincinnati RedsCincinnati Re | 6 - 4 | Houston AstrosHouston Astro |
| 23 Sep 00 | r00 | Cincinnati RedsCincinnati Re | 4 - 3 | Houston AstrosHouston Astro |
| 25 Sep 00 | r00 | Pittsburgh PiratesPittsburgh Pi | 9 - 4 | Houston AstrosHouston Astro |
| 26 Sep 00 | r00 | Pittsburgh PiratesPittsburgh Pi | 1 - 10 | Houston AstrosHouston Astro |
| 27 Sep 00 | r00 | Pittsburgh PiratesPittsburgh Pi | 3 - 2 | Houston AstrosHouston Astro |
| 28 Sep 00 | r00 | Houston AstrosHouston Astro | 3 - 13 | Milwaukee BrewersMilwaukee Bre |
| 29 Sep 00 | r00 | Houston AstrosHouston Astro | 7 - 6 | Milwaukee BrewersMilwaukee Bre |
| 30 Sep 00 | r00 | Houston AstrosHouston Astro | 6 - 1 | Milwaukee BrewersMilwaukee Bre |
Team 2000 Schedules
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