| 03 Mar 23 | r01        | New Zealand WarriorsNew Zealand W | 20 - 12 | Newcastle KnightsNewcastle Kni |
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| 12 Mar 23 | r02        | Wests TigersWests Tigers | 12 - 14 | Newcastle KnightsNewcastle Kni |
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| 17 Mar 23 | r03        | Newcastle KnightsNewcastle Kni | 20 - 36 | DolphinsDolphins |
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| 26 Mar 23 | r04        | Newcastle KnightsNewcastle Kni | 24 - 14 | Canberra RaidersCanberra Raid |
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| 01 Apr 23 | r05        | Manly Sea EaglesManly Sea Eag | 32 - 32 | Newcastle KnightsNewcastle Kni |
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| 09 Apr 23 | r06        | Newcastle KnightsNewcastle Kni | 34 - 24 | New Zealand WarriorsNew Zealand W |
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| 15 Apr 23 | r07        | Newcastle KnightsNewcastle Kni | 15 - 16 | Penrith PanthersPenrith Panth |
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| 22 Apr 23 | r08        | North Queensland CowboysNorth Queensl | 18 - 16 | Newcastle KnightsNewcastle Kni |
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| 28 Apr 23 | r09        | Parramatta EelsParramatta Ee | 43 - 12 | Newcastle KnightsNewcastle Kni |
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| 14 May 23 | r11        | Newcastle KnightsNewcastle Kni | 46 - 26 | Gold Coast TitansGold Coast Ti |
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| 20 May 23 | r12        | Cronulla SharksCronulla Shar | 26 - 6 | Newcastle KnightsNewcastle Kni |
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| 28 May 23 | r13        | Newcastle KnightsNewcastle Kni | 28 - 18 | Manly Sea EaglesManly Sea Eag |
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| 10 Jun 23 | r15        | Brisbane BroncosBrisbane Bron | 24 - 20 | Newcastle KnightsNewcastle Kni |
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| 17 Jun 23 | r16        | Newcastle KnightsNewcastle Kni | 16 - 18 | Sydney RoostersSydney Rooste |
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| 24 Jun 23 | r17        | Penrith PanthersPenrith Panth | 20 - 12 | Newcastle KnightsNewcastle Kni |
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| 02 Jul 23 | r18        | Canterbury Bankstown BullCanterbury Ba | 0 - 66 | Newcastle KnightsNewcastle Kni |
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| 14 Jul 23 | r20        | Newcastle KnightsNewcastle Kni | 34 - 18 | Wests TigersWests Tigers |
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| 22 Jul 23 | r21        | Newcastle KnightsNewcastle Kni | 26 - 18 | Melbourne StormMelbourne Sto |
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| 29 Jul 23 | r22        | Canberra RaidersCanberra Raid | 6 - 28 | Newcastle KnightsNewcastle Kni |
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| 05 Aug 23 | r23        | DolphinsDolphins | 28 - 30 | Newcastle KnightsNewcastle Kni |
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| 13 Aug 23 | r24        | Newcastle KnightsNewcastle Kni | 42 - 6 | Canterbury Bankstown BullCanterbury Ba |
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| 20 Aug 23 | r25        | Newcastle KnightsNewcastle Kni | 29 - 10 | South Sydney RabbitohsSouth Sydney |
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| 27 Aug 23 | r26        | Newcastle KnightsNewcastle Kni | 32 - 6 | Cronulla SharksCronulla Shar |
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| 02 Sep 23 | r27        | St. George Illawara DragoSt. George Il | 12 - 32 | Newcastle KnightsNewcastle Kni |
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| 10 Sep 23 | QF        | Newcastle KnightsNewcastle Kni | 30 - 28 | Canberra RaidersCanberra Raid |
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| 16 Sep 23 | SF        | New Zealand WarriorsNew Zealand W | 40 - 10 | Newcastle KnightsNewcastle Kni |