| 15 Mar 19 | r01        | Newcastle Knights Newcastle Kni | 14 - 8 | Cronulla SharksCronulla Shar |
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| 23 Mar 19 | r02        | Newcastle Knights Newcastle Kni | 14 - 16 | Penrith PanthersPenrith Panth |
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| 29 Mar 19 | r03        | Canberra RaidersCanberra Raid | 17 - 10 | Newcastle Knights Newcastle Kni |
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| 07 Apr 19 | r04        | Newcastle Knights Newcastle Kni | 12 - 13 | St. George Illawara DragoSt. George Il |
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| 13 Apr 19 | r05        | Newcastle Knights Newcastle Kni | 18 - 26 | Manly Sea EaglesManly Sea Eag |
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| 21 Apr 19 | r06        | Gold Coast TitansGold Coast Ti | 38 - 14 | Newcastle Knights Newcastle Kni |
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| 28 Apr 19 | r07        | Newcastle Knights Newcastle Kni | 28 - 14 | Parramatta EelsParramatta Ee |
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| 05 May 19 | r08        | New Zealand WarriorsNew Zealand W | 18 - 36 | Newcastle Knights Newcastle Kni |
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| 11 May 19 | r00        | Canterbury Bankstown BullCanterbury Ba | 10 - 22 | Newcastle Knights Newcastle Kni |
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| 19 May 19 | r10        | St. George Illawara DragoSt. George Il | 12 - 45 | Newcastle Knights Newcastle Kni |
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| 24 May 19 | r11        | Newcastle Knights Newcastle Kni | 38 - 12 | Sydney RoostersSydney Rooste |
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| 07 Jun 19 | r13        | South Sydney RabbitohsSouth Sydney | 12 - 20 | Newcastle Knights Newcastle Kni |
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| 15 Jun 19 | r14        | Melbourne StormMelbourne Sto | 34 - 4 | Newcastle Knights Newcastle Kni |
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| 29 Jun 19 | r15        | Newcastle Knights Newcastle Kni | 26 - 12 | Brisbane BroncosBrisbane Bron |
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| 06 Jul 19 | r16        | Newcastle Knights Newcastle Kni | 20 - 24 | New Zealand WarriorsNew Zealand W |
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| 12 Jul 19 | r17        | Newcastle Knights Newcastle Kni | 14 - 20 | Canterbury Bankstown BullCanterbury Ba |
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| 20 Jul 19 | r18        | Sydney RoostersSydney Rooste | 48 - 10 | Newcastle Knights Newcastle Kni |
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| 26 Jul 19 | r19        | Newcastle Knights Newcastle Kni | 26 - 28 | Wests TigersWests Tigers |
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| 03 Aug 19 | r20        | Manly Sea EaglesManly Sea Eag | 30 - 6 | Newcastle Knights Newcastle Kni |
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| 10 Aug 19 | r21        | Parramatta EelsParramatta Ee | 20 - 14 | Newcastle Knights Newcastle Kni |
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| 17 Aug 19 | r22        | Newcastle Knights Newcastle Kni | 42 - 6 | North Queensland Cowboys North Queensl |
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| 24 Aug 19 | r23        | Wests TigersWests Tigers | 46 - 4 | Newcastle Knights Newcastle Kni |
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| 31 Aug 19 | r24        | Newcastle Knights Newcastle Kni | 38 - 4 | Gold Coast TitansGold Coast Ti |
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| 08 Sep 19 | r25        | Penrith PanthersPenrith Panth | 54 - 10 | Newcastle Knights Newcastle Kni |