| 11 Feb 22 | r01    | Castleford TigersCastleford Ti | 16 - 26 | Salford Red DevilsSalford Red D |
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| 17 Feb 22 | r02  | Warrington WolvesWarrington Wo | 34 - 10 | Castleford TigersCastleford Ti |
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| 25 Feb 22 | r03 | Hull Kingston RoversHull Kingston | 26 - 10 | Castleford TigersCastleford Ti |
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| 06 Mar 22 | r04 | Castleford TigersCastleford Ti | 33 - 26 | Hull F.C.Hull F.C. |
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| 12 Mar 22 | r05 | Huddersfield GiantsHuddersfield | 36 - 24 | Castleford TigersCastleford Ti |
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| 17 Mar 22 | r06 | Wigan WarriorsWigan Warrior | 32 - 22 | Castleford TigersCastleford Ti |
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| 01 Apr 22 | r07 | Castleford TigersCastleford Ti | 32 - 6 | Toulouse OlympiqueToulouse Olym |
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| 14 Apr 22 | r08 | Wakefield Trinity WildcatWakefield Tri | 4 - 34 | Castleford TigersCastleford Ti |
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| 18 Apr 22 | r09 | Castleford TigersCastleford Ti | 16 - 14 | Leeds RhinosLeeds Rhinos |
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| 22 Apr 22 | r10 | Castleford TigersCastleford Ti | 30 - 10 | St HelensSt Helens |
| 29 Apr 22 | r10 | Catalans DragonsCatalans Drag | 44 - 12 | Castleford TigersCastleford Ti |
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| 15 May 22 | r12 | Castleford TigersCastleford Ti | 32 - 0 | Hull Kingston RoversHull Kingston |
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| 20 May 22 | r13 | Salford Red DevilsSalford Red D | 30 - 14 | Castleford TigersCastleford Ti |
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| 04 Jun 22 | r14 | Castleford TigersCastleford Ti | 12 - 32 | Wigan WarriorsWigan Warrior |
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| 12 Jun 22 | r15 | Toulouse OlympiqueToulouse Olym | 14 - 20 | Castleford TigersCastleford Ti |
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| 26 Jun 22 | r16 | Castleford TigersCastleford Ti | 17 - 16 | Catalans DragonsCatalans Drag |
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| 01 Jul 22 | r17 | Castleford TigersCastleford Ti | 26 - 18 | Huddersfield GiantsHuddersfield |
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| 09 Jul 22 | r18 | Leeds RhinosLeeds Rhinos | 34 - 20 | Castleford TigersCastleford Ti |
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| 16 Jul 22 | r19 | Castleford TigersCastleford Ti | 35 - 22 | Warrington WolvesWarrington Wo |
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| 22 Jul 22 | r20 | Hull F.C.Hull F.C. | 18 - 46 | Castleford TigersCastleford Ti |
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| 29 Jul 22 | r21 | Castleford TigersCastleford Ti | 6 - 32 | Wakefield Trinity WildcatWakefield Tri |
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| 07 Aug 22 | r20 | St HelensSt Helens | 20 - 12 | Castleford TigersCastleford Ti |
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| 12 Aug 22 | r23 | Castleford TigersCastleford Ti | 18 - 8 | Catalans DragonsCatalans Drag |
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| 18 Aug 22 | r24 | Huddersfield GiantsHuddersfield | 36 - 10 | Castleford TigersCastleford Ti |
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| 25 Aug 22 | r25 | Warrington WolvesWarrington Wo | 18 - 19 | Castleford TigersCastleford Ti |
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| 29 Aug 22 | r26 | Castleford TigersCastleford Ti | 10 - 50 | Salford Red DevilsSalford Red D |
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| 03 Sep 22 | r27 | Leeds RhinosLeeds Rhinos | 14 - 8 | Castleford TigersCastleford Ti |
Team 2022 Schedules
Bradford Bulls
Castleford Tigers
Catalans Dragons
Huddersfield Giants
Hull F.C.
Hull Kingston Rovers
Leeds Rhinos
Leigh Leopards
St Helens
Toulouse Olympique
Wakefield Trinity Wildcats
Warrington Wolves
Wigan Warriors
York City Knights
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