| 16 Jul 22 | r01        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | Holstein KielHolstein Kiel |
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| 23 Jul 22 | r02        | NurnbergNurnberg | 2 - 0 | SPVGG Greuther FürthSPVGG Greuthe |
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| 05 Aug 22 | r03        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 1 | KarlsruheKarlsruhe |
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| 14 Aug 22 | r04        | Fortuna DüsseldorfFortuna Düsse | 2 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 21 Aug 22 | r05        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 3 | KaiserslauternKaiserslauter |
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| 28 Aug 22 | r06        | HannoverHannover | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 03 Sep 22 | r07        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | St PauliSt Pauli |
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| 11 Sep 22 | r08        | MagdeburgMagdeburg | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 18 Sep 22 | r09        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 1 | PaderbornPaderborn |
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| 01 Oct 22 | r10        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 1 | SandhausenSandhausen |
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| 07 Oct 22 | r11        | Jahn RegensburgJahn Regensbu | 2 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 14 Oct 22 | r12        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | Hansa RostockHansa Rostock |
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| 23 Oct 22 | r13        | FC HeidenheimFC Heidenheim | 3 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 28 Oct 22 | r14        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 0 | BielefeldBielefeld |
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| 06 Nov 22 | r15        | BraunschweigBraunschweig | 0 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 09 Nov 22 | r16        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 0 | HamburgHamburg |
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| 13 Nov 22 | r17        | DarmstadtDarmstadt | 1 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 28 Jan 23 | r18        | Holstein KielHolstein Kiel | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 04 Feb 23 | r19        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 0 | NurnbergNurnberg |
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| 10 Feb 23 | r20        | KarlsruheKarlsruhe | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 18 Feb 23 | r21        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 1 | Fortuna DüsseldorfFortuna Düsse |
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| 25 Feb 23 | r22        | KaiserslauternKaiserslauter | 3 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 05 Mar 23 | r23        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 1 | HannoverHannover |
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| 11 Mar 23 | r24        | St PauliSt Pauli | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 18 Mar 23 | r25        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 0 | MagdeburgMagdeburg |
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| 02 Apr 23 | r26        | PaderbornPaderborn | 3 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 09 Apr 23 | r27        | SandhausenSandhausen | 0 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 14 Apr 23 | r28        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 1 | Jahn RegensburgJahn Regensbu |
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| 22 Apr 23 | r29        | Hansa RostockHansa Rostock | 2 - 0 | SPVGG Greuther FürthSPVGG Greuthe |
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| 28 Apr 23 | r30        | SPVGG Greuther FürthSPVGG Greuthe | 0 - 2 | FC HeidenheimFC Heidenheim |
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| 05 May 23 | r31        | BielefeldBielefeld | 1 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 13 May 23 | r32        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | BraunschweigBraunschweig |
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| 20 May 23 | r33        | HamburgHamburg | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 28 May 23 | r34        | SPVGG Greuther FürthSPVGG Greuthe | 4 - 0 | DarmstadtDarmstadt |