| 20 Sep 20 | r01        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 1 | OsnabrueckOsnabrueck |
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| 25 Sep 20 | r02        | AueAue | 1 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 04 Oct 20 | r03        | Wuerzburger KickersWuerzburger K | 2 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 17 Oct 20 | r04        | SPVGG Greuther FürthSPVGG Greuthe | 0 - 1 | HamburgHamburg |
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| 24 Oct 20 | r05        | Holstein KielHolstein Kiel | 1 - 3 | SPVGG Greuther FürthSPVGG Greuthe |
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| 01 Nov 20 | r06        | SPVGG Greuther FürthSPVGG Greuthe | 4 - 1 | HannoverHannover |
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| 07 Nov 20 | r07        | BochumBochum | 0 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 22 Nov 20 | r08        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 1 | Jahn RegensburgJahn Regensbu |
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| 29 Nov 20 | r09        | NurnbergNurnberg | 2 - 3 | SPVGG Greuther FürthSPVGG Greuthe |
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| 05 Dec 20 | r10        | SPVGG Greuther FürthSPVGG Greuthe | 0 - 1 | FC HeidenheimFC Heidenheim |
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| 11 Dec 20 | r11        | SandhausenSandhausen | 0 - 3 | SPVGG Greuther FürthSPVGG Greuthe |
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| 15 Dec 20 | r12        | SPVGG Greuther FürthSPVGG Greuthe | 0 - 4 | DarmstadtDarmstadt |
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| 19 Dec 20 | r13        | BraunschweigBraunschweig | 0 - 3 | SPVGG Greuther FürthSPVGG Greuthe |
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| 03 Jan 21 | r14        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 1 | St PauliSt Pauli |
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| 08 Jan 21 | r15        | KarlsruheKarlsruhe | 3 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 15 Jan 21 | r16        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 1 | PaderbornPaderborn |
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| 22 Jan 21 | r17        | Fortuna DüsseldorfFortuna Düsse | 3 - 3 | SPVGG Greuther FürthSPVGG Greuthe |
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| 26 Jan 21 | r18        | OsnabrueckOsnabrueck | 0 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 29 Jan 21 | r19        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 0 | AueAue |
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| 07 Feb 21 | r20        | SPVGG Greuther FürthSPVGG Greuthe | 4 - 1 | Wuerzburger KickersWuerzburger K |
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| 13 Feb 21 | r21        | HamburgHamburg | 0 - 0 | SPVGG Greuther FürthSPVGG Greuthe |
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| 22 Feb 21 | r22        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 1 | Holstein KielHolstein Kiel |
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| 27 Feb 21 | r23        | HannoverHannover | 2 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 06 Mar 21 | r24        | SPVGG Greuther FürthSPVGG Greuthe | 1 - 2 | BochumBochum |
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| 17 Mar 21 | r25        | Jahn RegensburgJahn Regensbu | 1 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 21 Mar 21 | r26        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | NurnbergNurnberg |
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| 03 Apr 21 | r27        | FC HeidenheimFC Heidenheim | 0 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 16 Apr 21 | r29        | DarmstadtDarmstadt | 2 - 2 | SPVGG Greuther FürthSPVGG Greuthe |
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| 20 Apr 21 | r30        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 0 | BraunschweigBraunschweig |
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| 25 Apr 21 | r31        | St PauliSt Pauli | 2 - 1 | SPVGG Greuther FürthSPVGG Greuthe |
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| 28 Apr 21 | r28        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 2 | SandhausenSandhausen |
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| 08 May 21 | r32        | SPVGG Greuther FürthSPVGG Greuthe | 2 - 2 | KarlsruheKarlsruhe |
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| 16 May 21 | r33        | PaderbornPaderborn | 2 - 4 | SPVGG Greuther FürthSPVGG Greuthe |
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| 23 May 21 | r34        | SPVGG Greuther FürthSPVGG Greuthe | 3 - 2 | Fortuna DüsseldorfFortuna Düsse |