| 06 Oct 91 | r06        | Chicago BearsChicago Bears | 7 - 20 | Washington CommandersWashington Co |
| 06 Oct 91 | r06        | Cincinnati BengalsCincinnati Be | 7 - 13 | Seattle SeahawksSeattle Seaha |
| 06 Oct 91 | r06        | Cleveland BrownsCleveland Bro | 14 - 17 | New York JetsNew York Jets |
| 06 Oct 91 | r06        | Detroit LionsDetroit Lions | 24 - 20 | Minnesota VikingsMinnesota Vik |
| 06 Oct 91 | r06        | Green Bay PackersGreen Bay Pac | 17 - 20 | Dallas CowboysDallas Cowboy |
| 06 Oct 91 | r06        | New England PatriotsNew England P | 10 - 20 | Miami DolphinsMiami Dolphin |
| 06 Oct 91 | r06        | Tampa Bay BuccaneersTampa Bay Buc | 14 - 13 | Philadelphia EaglesPhiladelphia |
| 06 Oct 91 | r06        | Tennessee TitansTennessee Tit | 42 - 14 | Denver BroncosDenver Bronco |
| 06 Oct 91 | r06        | Las Vegas RaidersLas Vegas Rai | 13 - 21 | Los Angeles ChargersLos Angeles C |
| 06 Oct 91 | r06        | New York GiantsNew York Gian | 20 - 9 | Arizona CardinalsArizona Cardi |
| 06 Oct 91 | r06        | Indianapolis ColtsIndianapolis | 3 - 21 | Pittsburgh SteelersPittsburgh St |
| 08 Oct 91 | r06        | Kansas City ChiefsKansas City C | 33 - 6 | Buffalo BillsBuffalo Bills |