| 04 Sep 79 | r01        | New England PatriotsNew England P | 13 - 16 | Pittsburgh SteelersPittsburgh St |
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| 09 Sep 79 | r02        | New England PatriotsNew England P | 56 - 3 | New York JetsNew York Jets |
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| 16 Sep 79 | r03        | Cincinnati BengalsCincinnati Be | 14 - 20 | New England PatriotsNew England P |
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| 23 Sep 79 | r04        | New England PatriotsNew England P | 27 - 21 | Los Angeles ChargersLos Angeles C |
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| 02 Oct 79 | r05        | Green Bay PackersGreen Bay Pac | 27 - 14 | New England PatriotsNew England P |
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| 07 Oct 79 | r06        | New England PatriotsNew England P | 24 - 17 | Detroit LionsDetroit Lions |
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| 14 Oct 79 | r07        | Chicago BearsChicago Bears | 7 - 27 | New England PatriotsNew England P |
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| 21 Oct 79 | r08        | New England PatriotsNew England P | 28 - 13 | Miami DolphinsMiami Dolphin |
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| 28 Oct 79 | r09        | Indianapolis ColtsIndianapolis | 31 - 26 | New England PatriotsNew England P |
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| 04 Nov 79 | r10        | Buffalo BillsBuffalo Bills | 6 - 26 | New England PatriotsNew England P |
| 11 Nov 79 | r10        | Denver BroncosDenver Bronco | 45 - 10 | New England PatriotsNew England P |
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| 18 Nov 79 | r12        | New England PatriotsNew England P | 50 - 21 | Indianapolis ColtsIndianapolis |
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| 25 Nov 79 | r13        | New England PatriotsNew England P | 13 - 16 | Buffalo BillsBuffalo Bills |
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| 30 Nov 79 | r14        | Miami DolphinsMiami Dolphin | 39 - 24 | New England PatriotsNew England P |
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| 09 Dec 79 | r15        | New York JetsNew York Jets | 27 - 26 | New England PatriotsNew England P |
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| 16 Dec 79 | r16        | New England PatriotsNew England P | 27 - 23 | Minnesota VikingsMinnesota Vik |