| 05 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 107 - 121 | Golden State WarriorsGolden State |
| 12 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 93 - 107 | Sacramento KingsSacramento Ki |
| 13 Oct 21 | r00        | Phoenix SunsPhoenix Suns | 119 - 74 | Portland Trail BlazersPortland Trai |
| 16 Oct 21 | r00        | Golden State WarriorsGolden State | 119 - 97 | Portland Trail BlazersPortland Trai |
| 21 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 121 - 124 | Sacramento KingsSacramento Ki |
| 24 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 134 - 105 | Phoenix SunsPhoenix Suns |
| 26 Oct 21 | r00        | Los Angeles ClippersLos Angeles C | 116 - 86 | Portland Trail BlazersPortland Trai |
| 28 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 116 - 96 | Memphis GrizzliesMemphis Grizz |
| 30 Oct 21 | r00        | Portland Trail BlazersPortland Trai | 111 - 92 | Los Angeles ClippersLos Angeles C |
| 31 Oct 21 | r00        | Charlotte HornetsCharlotte Hor | 125 - 113 | Portland Trail BlazersPortland Trai |
| 01 Nov 21 | r00        | Philadelphia 76ersPhiladelphia | 113 - 103 | Portland Trail BlazersPortland Trai |
| 03 Nov 21 | r00        | Cleveland CavaliersCleveland Cav | 107 - 104 | Portland Trail BlazersPortland Trai |
| 06 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 110 - 106 | Indiana PacersIndiana Pacer |
| 07 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 105 - 90 | Los Angeles LakersLos Angeles L |
| 10 Nov 21 | r00        | Los Angeles ClippersLos Angeles C | 117 - 109 | Portland Trail BlazersPortland Trai |
| 11 Nov 21 | r00        | Phoenix SunsPhoenix Suns | 119 - 109 | Portland Trail BlazersPortland Trai |
| 13 Nov 21 | r00        | Houston RocketsHouston Rocke | 92 - 104 | Portland Trail BlazersPortland Trai |
| 15 Nov 21 | r00        | Denver NuggetsDenver Nugget | 124 - 95 | Portland Trail BlazersPortland Trai |
| 16 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 118 - 113 | Toronto RaptorsToronto Rapto |
| 18 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 112 - 107 | Chicago BullsChicago Bulls |
| 21 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 118 - 111 | Philadelphia 76ersPhiladelphia |
| 24 Nov 21 | r00        | Portland Trail BlazersPortland Trai | 119 - 100 | Denver NuggetsDenver Nugget |
| 25 Nov 21 | r00        | Sacramento KingsSacramento Ki | 125 - 121 | Portland Trail BlazersPortland Trai |
| 27 Nov 21 | r00        | Golden State WarriorsGolden State | 118 - 103 | Portland Trail BlazersPortland Trai |
| 30 Nov 21 | r00        | Utah JazzUtah Jazz | 129 - 107 | Portland Trail BlazersPortland Trai |
| 01 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 110 - 92 | Detroit PistonsDetroit Pisto |
| 03 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 83 - 114 | San Antonio SpursSan Antonio S |
| 05 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 117 - 145 | Boston CelticsBoston Celtic |
| 07 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 90 - 102 | Los Angeles ClippersLos Angeles C |
| 09 Dec 21 | r00        | Golden State WarriorsGolden State | 104 - 94 | Portland Trail BlazersPortland Trai |
| 13 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 111 - 116 | Minnesota TimberwolvesMinnesota Tim |
| 15 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 107 - 111 | Phoenix SunsPhoenix Suns |
| 16 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 103 - 113 | Memphis GrizzliesMemphis Grizz |
| 18 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 125 - 116 | Charlotte HornetsCharlotte Hor |
| 19 Dec 21 | r00        | Memphis GrizzliesMemphis Grizz | 100 - 105 | Portland Trail BlazersPortland Trai |
| 22 Dec 21 | r00        | New Orleans PelicansNew Orleans P | 111 - 97 | Portland Trail BlazersPortland Trai |
| 28 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 117 - 132 | Dallas MavericksDallas Maveri |
| 30 Dec 21 | r00        | Portland Trail BlazersPortland Trai | 105 - 120 | Utah JazzUtah Jazz |
| 01 Jan 22 | r00        | Los Angeles LakersLos Angeles L | 139 - 106 | Portland Trail BlazersPortland Trai |
| 04 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 136 - 131 | Atlanta HawksAtlanta Hawks |
| 06 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 109 - 115 | Miami HeatMiami Heat |
| 08 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 101 - 114 | Cleveland CavaliersCleveland Cav |
| 10 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 103 - 88 | Sacramento KingsSacramento Ki |
| 11 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 114 - 108 | Brooklyn NetsBrooklyn Nets |
| 14 Jan 22 | r00        | Denver NuggetsDenver Nugget | 140 - 108 | Portland Trail BlazersPortland Trai |
| 16 Jan 22 | r00        | Washington WizardsWashington Wi | 110 - 115 | Portland Trail BlazersPortland Trai |
| 18 Jan 22 | r00        | Orlando MagicOrlando Magic | 88 - 98 | Portland Trail BlazersPortland Trai |
| 20 Jan 22 | r00        | Miami HeatMiami Heat | 104 - 92 | Portland Trail BlazersPortland Trai |
| 22 Jan 22 | r00        | Boston CelticsBoston Celtic | 105 - 109 | Portland Trail BlazersPortland Trai |
| 23 Jan 22 | r00        | Toronto RaptorsToronto Rapto | 105 - 114 | Portland Trail BlazersPortland Trai |
| 26 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 107 - 109 | Minnesota TimberwolvesMinnesota Tim |
| 27 Jan 22 | r00        | Portland Trail BlazersPortland Trai | 112 - 132 | Dallas MavericksDallas Maveri |
| 29 Jan 22 | r00        | Houston RocketsHouston Rocke | 110 - 125 | Portland Trail BlazersPortland Trai |
| 30 Jan 22 | r00        | Chicago BullsChicago Bulls | 130 - 116 | Portland Trail BlazersPortland Trai |
| 01 Feb 22 | r00        | Oklahoma City ThunderOklahoma City | 98 - 81 | Portland Trail BlazersPortland Trai |
| 03 Feb 22 | r00        | Los Angeles LakersLos Angeles L | 99 - 94 | Portland Trail BlazersPortland Trai |
| 05 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 93 - 96 | Oklahoma City ThunderOklahoma City |
| 06 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 108 - 137 | Milwaukee BucksMilwaukee Buc |
| 09 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 95 - 113 | Orlando MagicOrlando Magic |
| 10 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 107 - 105 | Los Angeles LakersLos Angeles L |
| 12 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 112 - 103 | New York KnicksNew York Knic |
| 15 Feb 22 | r00        | Milwaukee BucksMilwaukee Buc | 107 - 122 | Portland Trail BlazersPortland Trai |
| 17 Feb 22 | r00        | Memphis GrizzliesMemphis Grizz | 119 - 123 | Portland Trail BlazersPortland Trai |
| 25 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 95 - 132 | Golden State WarriorsGolden State |
| 28 Feb 22 | r00        | Portland Trail BlazersPortland Trai | 92 - 124 | Denver NuggetsDenver Nugget |
| 03 Mar 22 | r00        | Phoenix SunsPhoenix Suns | 120 - 90 | Portland Trail BlazersPortland Trai |
| 06 Mar 22 | r00        | Minnesota TimberwolvesMinnesota Tim | 135 - 121 | Portland Trail BlazersPortland Trai |
| 08 Mar 22 | r00        | Minnesota TimberwolvesMinnesota Tim | 124 - 81 | Portland Trail BlazersPortland Trai |
| 10 Mar 22 | r00        | Utah JazzUtah Jazz | 123 - 85 | Portland Trail BlazersPortland Trai |
| 13 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 127 - 118 | Washington WizardsWashington Wi |
| 14 Mar 22 | r00        | Atlanta HawksAtlanta Hawks | 122 - 113 | Portland Trail BlazersPortland Trai |
| 16 Mar 22 | r00        | New York KnicksNew York Knic | 128 - 98 | Portland Trail BlazersPortland Trai |
| 18 Mar 22 | r00        | Brooklyn NetsBrooklyn Nets | 128 - 123 | Portland Trail BlazersPortland Trai |
| 20 Mar 22 | r00        | Indiana PacersIndiana Pacer | 129 - 98 | Portland Trail BlazersPortland Trai |
| 21 Mar 22 | r00        | Detroit PistonsDetroit Pisto | 115 - 119 | Portland Trail BlazersPortland Trai |
| 24 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 96 - 133 | San Antonio SpursSan Antonio S |
| 26 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 106 - 125 | Houston RocketsHouston Rocke |
| 27 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 98 - 115 | Houston RocketsHouston Rocke |
| 29 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 131 - 134 | Oklahoma City ThunderOklahoma City |
| 31 Mar 22 | r00        | Portland Trail BlazersPortland Trai | 107 - 117 | New Orleans PelicansNew Orleans P |
| 02 Apr 22 | r00        | San Antonio SpursSan Antonio S | 130 - 111 | Portland Trail BlazersPortland Trai |
| 04 Apr 22 | r00        | San Antonio SpursSan Antonio S | 113 - 92 | Portland Trail BlazersPortland Trai |
| 06 Apr 22 | r00        | Oklahoma City ThunderOklahoma City | 98 - 94 | Portland Trail BlazersPortland Trai |
| 08 Apr 22 | r00        | New Orleans PelicansNew Orleans P | 127 - 94 | Portland Trail BlazersPortland Trai |
| 09 Apr 22 | r00        | Dallas MavericksDallas Maveri | 128 - 78 | Portland Trail BlazersPortland Trai |
| 11 Apr 22 | r00        | Portland Trail BlazersPortland Trai | 80 - 111 | Utah JazzUtah Jazz |