| 23 Jul 21 | r01    | FK RostovFK Rostov | 0 - 2 | Dinamo MoscowDinamo Moscow |
| 24 Jul 21 | r01 | Khimki FKKhimki FK | 1 - 3 | Zenit St PetersburgZenit St Pete |
| 24 Jul 21 | r01 | Lok. MoscowLok. Moscow | 3 - 1 | Arsenal TulaArsenal Tula |
| 24 Jul 21 | r01 | FK Rubin KazanFK Rubin Kaza | 1 - 0 | Spartak MoscowSpartak Mosco |
| 25 Jul 21 | r01 | Ural S.RUral S.R | 0 - 3 | FC KrasnodarFC Krasnodar |
| 25 Jul 21 | r01 | Krylya Sovetov SamaraKrylya Soveto | 1 - 2 | Terek GroznyTerek Grozny |
| 25 Jul 21 | r01 | CSKA MoscowCSKA Moscow | 1 - 0 | FC UfaFC Ufa |
| 26 Jul 21 | r01 | Nizhny NovgorodNizhny Novgor | 1 - 0 | PFC SochiPFC Sochi |
| |
| 30 Jul 21 | r02  | Krylya Sovetov SamaraKrylya Soveto | 0 - 1 | Spartak MoscowSpartak Mosco |
| 30 Jul 21 | r02 | Arsenal TulaArsenal Tula | 0 - 3 | FK Rubin KazanFK Rubin Kaza |
| 31 Jul 21 | r02 | FC UfaFC Ufa | 2 - 3 | Dinamo MoscowDinamo Moscow |
| 31 Jul 21 | r02 | CSKA MoscowCSKA Moscow | 1 - 2 | Lok. MoscowLok. Moscow |
| 01 Aug 21 | r02 | Ural S.RUral S.R | 1 - 1 | Nizhny NovgorodNizhny Novgor |
| 01 Aug 21 | r02 | FK RostovFK Rostov | 2 - 4 | Zenit St PetersburgZenit St Pete |
| 01 Aug 21 | r02 | FC KrasnodarFC Krasnodar | 0 - 1 | Khimki FKKhimki FK |
| 02 Aug 21 | r02 | Terek GroznyTerek Grozny | 1 - 2 | PFC SochiPFC Sochi |
| |
| 06 Aug 21 | r03 | FC UfaFC Ufa | 1 - 1 | Lok. MoscowLok. Moscow |
| 07 Aug 21 | r03 | Zenit St PetersburgZenit St Pete | 3 - 2 | FC KrasnodarFC Krasnodar |
| 07 Aug 21 | r03 | Arsenal TulaArsenal Tula | 2 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 07 Aug 21 | r03 | Spartak MoscowSpartak Mosco | 1 - 2 | Nizhny NovgorodNizhny Novgor |
| 08 Aug 21 | r03 | Khimki FKKhimki FK | 1 - 1 | FK RostovFK Rostov |
| 08 Aug 21 | r03 | Dinamo MoscowDinamo Moscow | 2 - 1 | CSKA MoscowCSKA Moscow |
| 08 Aug 21 | r03 | FK Rubin KazanFK Rubin Kaza | 2 - 1 | Terek GroznyTerek Grozny |
| 09 Aug 21 | r03 | PFC SochiPFC Sochi | 2 - 0 | Ural S.RUral S.R |
| |
| 14 Aug 21 | r04 | Spartak MoscowSpartak Mosco | 1 - 0 | Ural S.RUral S.R |
| 14 Aug 21 | r04 | Nizhny NovgorodNizhny Novgor | 1 - 2 | FC UfaFC Ufa |
| 14 Aug 21 | r04 | FK RostovFK Rostov | 1 - 3 | CSKA MoscowCSKA Moscow |
| 14 Aug 21 | r04 | Terek GroznyTerek Grozny | 2 - 1 | Dinamo MoscowDinamo Moscow |
| 15 Aug 21 | r04 | Lok. MoscowLok. Moscow | 1 - 1 | Zenit St PetersburgZenit St Pete |
| 15 Aug 21 | r04 | FC KrasnodarFC Krasnodar | 3 - 2 | Arsenal TulaArsenal Tula |
| 15 Aug 21 | r04 | FK Rubin KazanFK Rubin Kaza | 1 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 16 Aug 21 | r04 | PFC SochiPFC Sochi | 3 - 0 | Khimki FKKhimki FK |
| |
| 21 Aug 21 | r05 | CSKA MoscowCSKA Moscow | 2 - 0 | Terek GroznyTerek Grozny |
| 21 Aug 21 | r05 | Arsenal TulaArsenal Tula | 1 - 1 | Spartak MoscowSpartak Mosco |
| 21 Aug 21 | r05 | FC UfaFC Ufa | 1 - 1 | Zenit St PetersburgZenit St Pete |
| 21 Aug 21 | r05 | Ural S.RUral S.R | 0 - 1 | Dinamo MoscowDinamo Moscow |
| 21 Aug 21 | r05 | Krylya Sovetov SamaraKrylya Soveto | 1 - 0 | PFC SochiPFC Sochi |
| 22 Aug 21 | r05 | Lok. MoscowLok. Moscow | 2 - 1 | FC KrasnodarFC Krasnodar |
| 22 Aug 21 | r05 | Nizhny NovgorodNizhny Novgor | 1 - 2 | FK RostovFK Rostov |
| 22 Aug 21 | r05 | Khimki FKKhimki FK | 1 - 1 | FK Rubin KazanFK Rubin Kaza |
| |
| 26 Aug 21 | r06 | FC UfaFC Ufa | 1 - 2 | Krylya Sovetov SamaraKrylya Soveto |
| 26 Aug 21 | r06 | Spartak MoscowSpartak Mosco | 1 - 2 | PFC SochiPFC Sochi |
| 26 Aug 21 | r06 | Terek GroznyTerek Grozny | 2 - 1 | Arsenal TulaArsenal Tula |
| 26 Aug 21 | r06 | Zenit St PetersburgZenit St Pete | 1 - 0 | CSKA MoscowCSKA Moscow |
| 27 Aug 21 | r06 | Ural S.RUral S.R | 1 - 1 | FK RostovFK Rostov |
| 27 Aug 21 | r06 | Khimki FKKhimki FK | 1 - 1 | Nizhny NovgorodNizhny Novgor |
| 27 Aug 21 | r06 | Dinamo MoscowDinamo Moscow | 1 - 1 | Lok. MoscowLok. Moscow |
| 27 Aug 21 | r06 | FC KrasnodarFC Krasnodar | 2 - 0 | FK Rubin KazanFK Rubin Kaza |
| |
| 11 Sep 21 | r07 | Lok. MoscowLok. Moscow | 2 - 0 | Krylya Sovetov SamaraKrylya Soveto |
| 11 Sep 21 | r07 | Zenit St PetersburgZenit St Pete | 3 - 1 | Terek GroznyTerek Grozny |
| 11 Sep 21 | r07 | Spartak MoscowSpartak Mosco | 3 - 1 | Khimki FKKhimki FK |
| 12 Sep 21 | r07 | Arsenal TulaArsenal Tula | 2 - 2 | CSKA MoscowCSKA Moscow |
| 12 Sep 21 | r07 | PFC SochiPFC Sochi | 3 - 1 | FC UfaFC Ufa |
| 12 Sep 21 | r07 | Dinamo MoscowDinamo Moscow | 1 - 2 | Nizhny NovgorodNizhny Novgor |
| 13 Sep 21 | r07 | FK Rubin KazanFK Rubin Kaza | 4 - 0 | Ural S.RUral S.R |
| 13 Sep 21 | r07 | FK RostovFK Rostov | 1 - 1 | FC KrasnodarFC Krasnodar |
| |
| 18 Sep 21 | r08 | FC UfaFC Ufa | 3 - 2 | Khimki FKKhimki FK |
| 18 Sep 21 | r08 | Krylya Sovetov SamaraKrylya Soveto | 4 - 2 | FK RostovFK Rostov |
| 18 Sep 21 | r08 | Terek GroznyTerek Grozny | 0 - 2 | FC KrasnodarFC Krasnodar |
| 19 Sep 21 | r08 | Nizhny NovgorodNizhny Novgor | 2 - 3 | Arsenal TulaArsenal Tula |
| 19 Sep 21 | r08 | PFC SochiPFC Sochi | 0 - 1 | Dinamo MoscowDinamo Moscow |
| 20 Sep 21 | r08 | Ural S.RUral S.R | 0 - 0 | Lok. MoscowLok. Moscow |
| 20 Sep 21 | r08 | FK Rubin KazanFK Rubin Kaza | 1 - 3 | Zenit St PetersburgZenit St Pete |
| 20 Sep 21 | r08 | CSKA MoscowCSKA Moscow | 1 - 0 | Spartak MoscowSpartak Mosco |
| |
| 25 Sep 21 | r09  | Khimki FKKhimki FK | 0 - 0 | Lok. MoscowLok. Moscow |
| 25 Sep 21 | r09 | Zenit St PetersburgZenit St Pete | 2 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 25 Sep 21 | r09 | Spartak MoscowSpartak Mosco | 2 - 0 | FC UfaFC Ufa |
| 26 Sep 21 | r09 | Dinamo MoscowDinamo Moscow | 2 - 0 | FK Rubin KazanFK Rubin Kaza |
| 26 Sep 21 | r09 | FK RostovFK Rostov | 1 - 2 | Terek GroznyTerek Grozny |
| 26 Sep 21 | r09 | FC KrasnodarFC Krasnodar | 3 - 0 | PFC SochiPFC Sochi |
| 27 Sep 21 | r09 | Ural S.RUral S.R | 2 - 0 | Arsenal TulaArsenal Tula |
| 27 Sep 21 | r09 | Nizhny NovgorodNizhny Novgor | 0 - 2 | CSKA MoscowCSKA Moscow |
| |
| 02 Oct 21 | r10 | FK Rubin KazanFK Rubin Kaza | 0 - 1 | Nizhny NovgorodNizhny Novgor |
| 02 Oct 21 | r10 | Dinamo MoscowDinamo Moscow | 0 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 02 Oct 21 | r10 | CSKA MoscowCSKA Moscow | 0 - 0 | FC KrasnodarFC Krasnodar |
| 02 Oct 21 | r10 | Arsenal TulaArsenal Tula | 0 - 0 | Khimki FKKhimki FK |
| 03 Oct 21 | r10 | FC UfaFC Ufa | 0 - 1 | Ural S.RUral S.R |
| 03 Oct 21 | r10 | Zenit St PetersburgZenit St Pete | 1 - 2 | PFC SochiPFC Sochi |
| 03 Oct 21 | r10 | Lok. MoscowLok. Moscow | 1 - 2 | FK RostovFK Rostov |
| 03 Oct 21 | r10 | Terek GroznyTerek Grozny | 0 - 1 | Spartak MoscowSpartak Mosco |
| |
| 16 Oct 21 | r11 | Arsenal TulaArsenal Tula | 2 - 1 | Zenit St PetersburgZenit St Pete |
| 16 Oct 21 | r11 | FK Rubin KazanFK Rubin Kaza | 2 - 2 | Lok. MoscowLok. Moscow |
| 16 Oct 21 | r11 | Spartak MoscowSpartak Mosco | 2 - 2 | Dinamo MoscowDinamo Moscow |
| 16 Oct 21 | r11 | PFC SochiPFC Sochi | 3 - 2 | FK RostovFK Rostov |
| 17 Oct 21 | r11 | Ural S.RUral S.R | 0 - 1 | CSKA MoscowCSKA Moscow |
| 17 Oct 21 | r11 | Krylya Sovetov SamaraKrylya Soveto | 2 - 0 | Nizhny NovgorodNizhny Novgor |
| 17 Oct 21 | r11 | Khimki FKKhimki FK | 2 - 0 | Terek GroznyTerek Grozny |
| 17 Oct 21 | r11 | FC KrasnodarFC Krasnodar | 1 - 1 | FC UfaFC Ufa |
| |
| 22 Oct 21 | r12 | Dinamo MoscowDinamo Moscow | 4 - 1 | Khimki FKKhimki FK |
| 23 Oct 21 | r12 | Nizhny NovgorodNizhny Novgor | 1 - 4 | FC KrasnodarFC Krasnodar |
| 23 Oct 21 | r12 | FK RostovFK Rostov | 4 - 0 | Arsenal TulaArsenal Tula |
| 23 Oct 21 | r12 | CSKA MoscowCSKA Moscow | 3 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 24 Oct 21 | r12 | FC UfaFC Ufa | 1 - 1 | FK Rubin KazanFK Rubin Kaza |
| 24 Oct 21 | r12 | Terek GroznyTerek Grozny | 1 - 0 | Ural S.RUral S.R |
| 24 Oct 21 | r12 | Zenit St PetersburgZenit St Pete | 7 - 1 | Spartak MoscowSpartak Mosco |
| 25 Oct 21 | r12 | Lok. MoscowLok. Moscow | 2 - 1 | PFC SochiPFC Sochi |
| |
| 29 Oct 21 | r13 | Zenit St PetersburgZenit St Pete | 4 - 1 | Dinamo MoscowDinamo Moscow |
| 30 Oct 21 | r13 | FK Rubin KazanFK Rubin Kaza | 1 - 0 | CSKA MoscowCSKA Moscow |
| 30 Oct 21 | r13 | Spartak MoscowSpartak Mosco | 1 - 1 | FK RostovFK Rostov |
| 30 Oct 21 | r13 | FC KrasnodarFC Krasnodar | 0 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 30 Oct 21 | r13 | Nizhny NovgorodNizhny Novgor | 1 - 2 | Lok. MoscowLok. Moscow |
| 31 Oct 21 | r13 | FC UfaFC Ufa | 1 - 0 | Terek GroznyTerek Grozny |
| 31 Oct 21 | r13 | Arsenal TulaArsenal Tula | 1 - 2 | PFC SochiPFC Sochi |
| 31 Oct 21 | r13 | Khimki FKKhimki FK | 0 - 0 | Ural S.RUral S.R |
| |
| 06 Nov 21 | r14 | Arsenal TulaArsenal Tula | 0 - 0 | FC UfaFC Ufa |
| 06 Nov 21 | r14 | Krylya Sovetov SamaraKrylya Soveto | 3 - 0 | Khimki FKKhimki FK |
| 06 Nov 21 | r14 | Dinamo MoscowDinamo Moscow | 1 - 0 | FC KrasnodarFC Krasnodar |
| 06 Nov 21 | r14 | PFC SochiPFC Sochi | 4 - 1 | CSKA MoscowCSKA Moscow |
| 07 Nov 21 | r14 | Ural S.RUral S.R | 0 - 0 | Zenit St PetersburgZenit St Pete |
| 07 Nov 21 | r14 | FK RostovFK Rostov | 5 - 1 | FK Rubin KazanFK Rubin Kaza |
| 07 Nov 21 | r14 | Spartak MoscowSpartak Mosco | 1 - 1 | Lok. MoscowLok. Moscow |
| 07 Nov 21 | r14 | Terek GroznyTerek Grozny | 3 - 1 | Nizhny NovgorodNizhny Novgor |
| |
| 19 Nov 21 | r15 | Zenit St PetersburgZenit St Pete | 5 - 1 | Nizhny NovgorodNizhny Novgor |
| 20 Nov 21 | r15 | Krylya Sovetov SamaraKrylya Soveto | 1 - 1 | Ural S.RUral S.R |
| 20 Nov 21 | r15 | Lok. MoscowLok. Moscow | 1 - 2 | Terek GroznyTerek Grozny |
| 20 Nov 21 | r15 | FC KrasnodarFC Krasnodar | 2 - 1 | Spartak MoscowSpartak Mosco |
| 21 Nov 21 | r15 | FK RostovFK Rostov | 2 - 2 | FC UfaFC Ufa |
| 21 Nov 21 | r15 | CSKA MoscowCSKA Moscow | 0 - 0 | Khimki FKKhimki FK |
| 21 Nov 21 | r15 | Dinamo MoscowDinamo Moscow | 5 - 1 | Arsenal TulaArsenal Tula |
| 21 Nov 21 | r15 | PFC SochiPFC Sochi | 1 - 2 | FK Rubin KazanFK Rubin Kaza |
| |
| 27 Nov 21 | r16 | Ural S.RUral S.R | 1 - 1 | PFC SochiPFC Sochi |
| 27 Nov 21 | r16 | Terek GroznyTerek Grozny | 2 - 0 | FK RostovFK Rostov |
| 27 Nov 21 | r16 | Khimki FKKhimki FK | 3 - 3 | FC KrasnodarFC Krasnodar |
| 28 Nov 21 | r16 | Nizhny NovgorodNizhny Novgor | 0 - 0 | Krylya Sovetov SamaraKrylya Soveto |
| 28 Nov 21 | r16 | FK Rubin KazanFK Rubin Kaza | 2 - 3 | Dinamo MoscowDinamo Moscow |
| 28 Nov 21 | r16 | CSKA MoscowCSKA Moscow | 0 - 2 | Zenit St PetersburgZenit St Pete |
| 29 Nov 21 | r16 | FC UfaFC Ufa | 1 - 1 | Spartak MoscowSpartak Mosco |
| 29 Nov 21 | r16 | Arsenal TulaArsenal Tula | 3 - 1 | Lok. MoscowLok. Moscow |
| |
| 03 Dec 21 | r17 | Zenit St PetersburgZenit St Pete | 2 - 2 | FK RostovFK Rostov |
| 04 Dec 21 | r17 | Krylya Sovetov SamaraKrylya Soveto | 0 - 1 | CSKA MoscowCSKA Moscow |
| 04 Dec 21 | r17 | Spartak MoscowSpartak Mosco | 2 - 1 | Terek GroznyTerek Grozny |
| 04 Dec 21 | r17 | Lok. MoscowLok. Moscow | 0 - 1 | Ural S.RUral S.R |
| 05 Dec 21 | r17 | Khimki FKKhimki FK | 1 - 2 | Arsenal TulaArsenal Tula |
| 05 Dec 21 | r17 | Dinamo MoscowDinamo Moscow | 2 - 0 | FC UfaFC Ufa |
| 05 Dec 21 | r17 | Nizhny NovgorodNizhny Novgor | 2 - 1 | FK Rubin KazanFK Rubin Kaza |
| 05 Dec 21 | r17 | PFC SochiPFC Sochi | 1 - 2 | FC KrasnodarFC Krasnodar |
| |
| 11 Dec 21 | r18 | Krylya Sovetov SamaraKrylya Soveto | 2 - 0 | FK Rubin KazanFK Rubin Kaza |
| 11 Dec 21 | r18 | CSKA MoscowCSKA Moscow | 2 - 0 | Arsenal TulaArsenal Tula |
| 11 Dec 21 | r18 | FK RostovFK Rostov | 1 - 4 | Ural S.RUral S.R |
| 12 Dec 21 | r18 | Dinamo MoscowDinamo Moscow | 1 - 1 | Zenit St PetersburgZenit St Pete |
| 12 Dec 21 | r18 | Terek GroznyTerek Grozny | 4 - 1 | Khimki FKKhimki FK |
| 12 Dec 21 | r18 | FC KrasnodarFC Krasnodar | 0 - 0 | Nizhny NovgorodNizhny Novgor |
| 12 Dec 21 | r18 | Lok. MoscowLok. Moscow | 2 - 0 | FC UfaFC Ufa |
| 13 Dec 21 | r18 | PFC SochiPFC Sochi | 3 - 0 | Spartak MoscowSpartak Mosco |
| |
| 26 Feb 22 | r19 | Nizhny NovgorodNizhny Novgor | 1 - 0 | Ural S.RUral S.R |
| 26 Feb 22 | r19 | Khimki FKKhimki FK | 0 - 3 | Dinamo MoscowDinamo Moscow |
| 26 Feb 22 | r19 | PFC SochiPFC Sochi | 2 - 0 | Arsenal TulaArsenal Tula |
| 26 Feb 22 | r19 | Spartak MoscowSpartak Mosco | 0 - 2 | CSKA MoscowCSKA Moscow |
| 27 Feb 22 | r19 | Terek GroznyTerek Grozny | 2 - 1 | FC UfaFC Ufa |
| 28 Feb 22 | r19 | Zenit St PetersburgZenit St Pete | 3 - 2 | FK Rubin KazanFK Rubin Kaza |
| |
| 05 Mar 22 | r20 | CSKA MoscowCSKA Moscow | 1 - 0 | Nizhny NovgorodNizhny Novgor |
| 06 Mar 22 | r20 | Krylya Sovetov SamaraKrylya Soveto | 2 - 2 | Arsenal TulaArsenal Tula |
| 06 Mar 22 | r20 | Lok. MoscowLok. Moscow | 3 - 2 | Khimki FKKhimki FK |
| 06 Mar 22 | r20 | Dinamo MoscowDinamo Moscow | 0 - 2 | Spartak MoscowSpartak Mosco |
| 07 Mar 22 | r20 | FC KrasnodarFC Krasnodar | 2 - 1 | Ural S.RUral S.R |
| 07 Mar 22 | r20 | Zenit St PetersburgZenit St Pete | 2 - 0 | FC UfaFC Ufa |
| 07 Mar 22 | r20 | FK RostovFK Rostov | 0 - 1 | PFC SochiPFC Sochi |
| 07 Mar 22 | r20 | Terek GroznyTerek Grozny | 1 - 2 | FK Rubin KazanFK Rubin Kaza |
| |
| 12 Mar 22 | r21 | FC UfaFC Ufa | 0 - 0 | Nizhny NovgorodNizhny Novgor |
| 12 Mar 22 | r21 | Arsenal TulaArsenal Tula | 1 - 4 | Dinamo MoscowDinamo Moscow |
| 12 Mar 22 | r21 | Lok. MoscowLok. Moscow | 1 - 2 | CSKA MoscowCSKA Moscow |
| 13 Mar 22 | r21 | Ural S.RUral S.R | 0 - 0 | Terek GroznyTerek Grozny |
| 13 Mar 22 | r21 | Khimki FKKhimki FK | 0 - 0 | PFC SochiPFC Sochi |
| 13 Mar 22 | r21 | Krylya Sovetov SamaraKrylya Soveto | 1 - 1 | Zenit St PetersburgZenit St Pete |
| 13 Mar 22 | r21 | Spartak MoscowSpartak Mosco | 1 - 2 | FC KrasnodarFC Krasnodar |
| 14 Mar 22 | r21 | FK Rubin KazanFK Rubin Kaza | 1 - 2 | FK RostovFK Rostov |
| |
| 19 Mar 22 | r22 | Ural S.RUral S.R | 0 - 1 | Khimki FKKhimki FK |
| 19 Mar 22 | r22 | Nizhny NovgorodNizhny Novgor | 1 - 1 | Spartak MoscowSpartak Mosco |
| 19 Mar 22 | r22 | Terek GroznyTerek Grozny | 2 - 3 | Lok. MoscowLok. Moscow |
| 19 Mar 22 | r22 | Zenit St PetersburgZenit St Pete | 3 - 0 | Arsenal TulaArsenal Tula |
| 20 Mar 22 | r22 | CSKA MoscowCSKA Moscow | 6 - 1 | FK Rubin KazanFK Rubin Kaza |
| 20 Mar 22 | r22 | FC UfaFC Ufa | 1 - 1 | FC KrasnodarFC Krasnodar |
| 20 Mar 22 | r22 | PFC SochiPFC Sochi | 2 - 3 | Krylya Sovetov SamaraKrylya Soveto |
| 20 Mar 22 | r22 | Dinamo MoscowDinamo Moscow | 1 - 1 | FK RostovFK Rostov |
| |
| 01 Apr 22 | r23 | FK Rubin KazanFK Rubin Kaza | 2 - 3 | Khimki FKKhimki FK |
| 02 Apr 22 | r23 | Krylya Sovetov SamaraKrylya Soveto | 1 - 2 | FC UfaFC Ufa |
| 02 Apr 22 | r23 | Arsenal TulaArsenal Tula | 0 - 0 | Terek GroznyTerek Grozny |
| 02 Apr 22 | r23 | FK RostovFK Rostov | 1 - 2 | Nizhny NovgorodNizhny Novgor |
| 02 Apr 22 | r23 | Lok. MoscowLok. Moscow | 1 - 0 | Spartak MoscowSpartak Mosco |
| 03 Apr 22 | r23 | FC KrasnodarFC Krasnodar | 0 - 1 | Dinamo MoscowDinamo Moscow |
| 03 Apr 22 | r23 | CSKA MoscowCSKA Moscow | 2 - 2 | Ural S.RUral S.R |
| 03 Apr 22 | r23 | PFC SochiPFC Sochi | 0 - 0 | Zenit St PetersburgZenit St Pete |
| |
| 06 Apr 22 | r19 | FK RostovFK Rostov | 1 - 0 | Krylya Sovetov SamaraKrylya Soveto |
| |
| 09 Apr 22 | r24 | Nizhny NovgorodNizhny Novgor | 0 - 1 | Dinamo MoscowDinamo Moscow |
| 09 Apr 22 | r24 | Khimki FKKhimki FK | 4 - 2 | CSKA MoscowCSKA Moscow |
| 09 Apr 22 | r24 | FK Rubin KazanFK Rubin Kaza | 0 - 1 | FC KrasnodarFC Krasnodar |
| 09 Apr 22 | r24 | Terek GroznyTerek Grozny | 0 - 2 | Zenit St PetersburgZenit St Pete |
| 10 Apr 22 | r24 | Ural S.RUral S.R | 0 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 10 Apr 22 | r24 | FC UfaFC Ufa | 1 - 2 | PFC SochiPFC Sochi |
| 10 Apr 22 | r24 | Spartak MoscowSpartak Mosco | 3 - 0 | Arsenal TulaArsenal Tula |
| 10 Apr 22 | r24 | FK RostovFK Rostov | 4 - 1 | Lok. MoscowLok. Moscow |
| |
| 15 Apr 22 | r25 | Dinamo MoscowDinamo Moscow | 2 - 0 | Terek GroznyTerek Grozny |
| 16 Apr 22 | r25 | FC UfaFC Ufa | 1 - 1 | CSKA MoscowCSKA Moscow |
| 16 Apr 22 | r25 | Zenit St PetersburgZenit St Pete | 3 - 1 | Ural S.RUral S.R |
| 16 Apr 22 | r25 | Spartak MoscowSpartak Mosco | 1 - 1 | FK Rubin KazanFK Rubin Kaza |
| 17 Apr 22 | r25 | Arsenal TulaArsenal Tula | 1 - 2 | FK RostovFK Rostov |
| 17 Apr 22 | r25 | Krylya Sovetov SamaraKrylya Soveto | 2 - 0 | FC KrasnodarFC Krasnodar |
| 17 Apr 22 | r25 | PFC SochiPFC Sochi | 2 - 2 | Lok. MoscowLok. Moscow |
| 17 Apr 22 | r25 | Nizhny NovgorodNizhny Novgor | 0 - 0 | Khimki FKKhimki FK |
| |
| 23 Apr 22 | r26 | Ural S.RUral S.R | 2 - 1 | FC UfaFC Ufa |
| 23 Apr 22 | r26 | Lok. MoscowLok. Moscow | 2 - 1 | Nizhny NovgorodNizhny Novgor |
| 23 Apr 22 | r26 | PFC SochiPFC Sochi | 3 - 2 | Terek GroznyTerek Grozny |
| 24 Apr 22 | r26 | FK Rubin KazanFK Rubin Kaza | 1 - 0 | Arsenal TulaArsenal Tula |
| 24 Apr 22 | r26 | Khimki FKKhimki FK | 4 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 24 Apr 22 | r26 | FK RostovFK Rostov | 3 - 2 | Spartak MoscowSpartak Mosco |
| 24 Apr 22 | r26 | CSKA MoscowCSKA Moscow | 1 - 0 | Dinamo MoscowDinamo Moscow |
| 25 Apr 22 | r26 | FC KrasnodarFC Krasnodar | 1 - 3 | Zenit St PetersburgZenit St Pete |
| |
| 30 Apr 22 | r27 | Dinamo MoscowDinamo Moscow | 2 - 3 | Ural S.RUral S.R |
| 30 Apr 22 | r27 | FK Rubin KazanFK Rubin Kaza | 0 - 6 | PFC SochiPFC Sochi |
| 30 Apr 22 | r27 | FC KrasnodarFC Krasnodar | 2 - 1 | FK RostovFK Rostov |
| 30 Apr 22 | r27 | Zenit St PetersburgZenit St Pete | 3 - 1 | Lok. MoscowLok. Moscow |
| 01 May 22 | r27 | Spartak MoscowSpartak Mosco | 2 - 1 | Krylya Sovetov SamaraKrylya Soveto |
| 01 May 22 | r27 | Khimki FKKhimki FK | 1 - 1 | FC UfaFC Ufa |
| 01 May 22 | r27 | Terek GroznyTerek Grozny | 2 - 0 | CSKA MoscowCSKA Moscow |
| 02 May 22 | r27 | Arsenal TulaArsenal Tula | 2 - 2 | Nizhny NovgorodNizhny Novgor |
| |
| 04 May 22 | r19 | FC KrasnodarFC Krasnodar | 1 - 0 | Lok. MoscowLok. Moscow |
| |
| 06 May 22 | r28 | Krylya Sovetov SamaraKrylya Soveto | 5 - 2 | Dinamo MoscowDinamo Moscow |
| 07 May 22 | r28 | Ural S.RUral S.R | 1 - 3 | Spartak MoscowSpartak Mosco |
| 07 May 22 | r28 | Zenit St PetersburgZenit St Pete | 1 - 0 | Khimki FKKhimki FK |
| 07 May 22 | r28 | Nizhny NovgorodNizhny Novgor | 0 - 1 | Terek GroznyTerek Grozny |
| 07 May 22 | r28 | CSKA MoscowCSKA Moscow | 0 - 1 | PFC SochiPFC Sochi |
| 08 May 22 | r28 | FC UfaFC Ufa | 0 - 0 | FK RostovFK Rostov |
| 08 May 22 | r28 | Arsenal TulaArsenal Tula | 1 - 1 | FC KrasnodarFC Krasnodar |
| 08 May 22 | r28 | Lok. MoscowLok. Moscow | 1 - 0 | FK Rubin KazanFK Rubin Kaza |
| |
| 13 May 22 | r29 | PFC SochiPFC Sochi | 0 - 0 | Nizhny NovgorodNizhny Novgor |
| 14 May 22 | r29 | FC UfaFC Ufa | 2 - 1 | Arsenal TulaArsenal Tula |
| 14 May 22 | r29 | FK RostovFK Rostov | 2 - 1 | Khimki FKKhimki FK |
| 14 May 22 | r29 | Lok. MoscowLok. Moscow | 3 - 3 | Dinamo MoscowDinamo Moscow |
| 14 May 22 | r29 | Terek GroznyTerek Grozny | 1 - 0 | Krylya Sovetov SamaraKrylya Soveto |
| 15 May 22 | r29 | Ural S.RUral S.R | 3 - 0 | FK Rubin KazanFK Rubin Kaza |
| 15 May 22 | r29 | Spartak MoscowSpartak Mosco | 1 - 1 | Zenit St PetersburgZenit St Pete |
| 15 May 22 | r29 | FC KrasnodarFC Krasnodar | 1 - 0 | CSKA MoscowCSKA Moscow |
| |
| 21 May 22 | r30 | FC KrasnodarFC Krasnodar | 1 - 1 | Terek GroznyTerek Grozny |
| 21 May 22 | r30 | Krylya Sovetov SamaraKrylya Soveto | 0 - 1 | Lok. MoscowLok. Moscow |
| 21 May 22 | r30 | CSKA MoscowCSKA Moscow | 4 - 0 | FK RostovFK Rostov |
| 21 May 22 | r30 | Dinamo MoscowDinamo Moscow | 1 - 5 | PFC SochiPFC Sochi |
| 21 May 22 | r30 | FK Rubin KazanFK Rubin Kaza | 1 - 2 | FC UfaFC Ufa |
| 21 May 22 | r30 | Arsenal TulaArsenal Tula | 1 - 2 | Ural S.RUral S.R |
| 21 May 22 | r30 | Nizhny NovgorodNizhny Novgor | 1 - 0 | Zenit St PetersburgZenit St Pete |
| 21 May 22 | r30 | Khimki FKKhimki FK | 2 - 1 | Spartak MoscowSpartak Mosco |
| |
| 25 May 22 | r00 | SKA-KhabarovskSKA-Khabarovs | 1 - 0 | Khimki FKKhimki FK |
| 25 May 22 | r00 | Gazovik OrenburgGazovik Orenb | 2 - 2 | FC UfaFC Ufa |
| 28 May 22 | r00 | Khimki FKKhimki FK | 3 - 0 | SKA-KhabarovskSKA-Khabarovs |
| 28 May 22 | r00 | FC UfaFC Ufa | 1 - 2 | Gazovik OrenburgGazovik Orenb |
Team 2021-2022 Schedules
Akhmat Grozny
Akron Tolyatti
Baltika Kaliningrad
CSKA Moscow
Dynamo Makhachkala
Dynamo Moscow
Krasnodar
Krylia Sovetov Samara
Lokomotiv Moscow
Nizhny Novgorod
Orenburg
Rostov
Rubin Kazan
Sochi
Spartak Moscow
Zenit Saint Petersburg
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