| 05 Jul 24 | r01     | PueblaPuebla | 1 - 0 | SantosSantos |
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| 14 Jul 24 | r02  | SantosSantos | 1 - 1 | PumasPumas |
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| 17 Jul 24 | r03 | AtlasAtlas | 1 - 0 | SantosSantos |
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| 21 Jul 24 | r04 | SantosSantos | 0 - 3 | TigresTigres |
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| 19 Aug 24 | r08 | TijuanaTijuana | 3 - 1 | SantosSantos |
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| 25 Aug 24 | r05 | LeonLeon | 1 - 1 | SantosSantos |
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| 02 Sep 24 | r06 | SantosSantos | 3 - 2 | NecaxaNecaxa |
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| 15 Sep 24 | r07 | SantosSantos | 0 - 2 | MonterreyMonterrey |
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| 23 Sep 24 | r09 | SantosSantos | 2 - 0 | TolucaToluca |
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| 29 Sep 24 | r10 | Atletico de San LuisAtletico de S | 3 - 1 | SantosSantos |
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| 07 Oct 24 | r11 | SantosSantos | 0 - 2 | FC JuarezFC Juarez |
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| 20 Oct 24 | r12 | CF AmericaCF America | 3 - 0 | SantosSantos |
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| 23 Oct 24 | r13 | SantosSantos | 1 - 1 | PachucaPachuca |
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| 26 Oct 24 | r14 | SantosSantos | 0 - 0 | MazatlánMazatlán |
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| 03 Nov 24 | r15 | Cruz AzulCruz Azul | 2 - 0 | SantosSantos |
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| 06 Nov 24 | r16 | SantosSantos | 0 - 2 | CD GuadalajaraCD Guadalajar |
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| 09 Nov 24 | r17 | Queretaro FCQueretaro FC | 3 - 2 | SantosSantos |
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| 12 Jan 25 | r01 | CD GuadalajaraCD Guadalajar | 1 - 0 | Santos LagunaSantos Laguna |
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| 21 Jan 25 | r02 | PachucaPachuca | 2 - 1 | Santos LagunaSantos Laguna |
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| 26 Jan 25 | r03 | Santos LagunaSantos Laguna | 1 - 4 | CF AmericaCF America |
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| 30 Jan 25 | r04 | FC JuarezFC Juarez | 1 - 0 | Santos LagunaSantos Laguna |
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| 02 Feb 25 | r05 | Santos LagunaSantos Laguna | 0 - 2 | PueblaPuebla |
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| 08 Feb 25 | r06 | NecaxaNecaxa | 3 - 2 | Santos LagunaSantos Laguna |
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| 15 Feb 25 | r07 | MazatlánMazatlán | 1 - 1 | Santos LagunaSantos Laguna |
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| 20 Feb 25 | r09 | Santos LagunaSantos Laguna | 0 - 1 | Cruz AzulCruz Azul |
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| 23 Feb 25 | r08 | Santos LagunaSantos Laguna | 2 - 0 | AtlasAtlas |
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| 03 Mar 25 | r10 | MonterreyMonterrey | 4 - 2 | Santos LagunaSantos Laguna |
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| 09 Mar 25 | r11 | Santos LagunaSantos Laguna | 2 - 1 | LeónLeón |
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| 15 Mar 25 | r12 | TigresTigres | 3 - 0 | Santos LagunaSantos Laguna |
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| 30 Mar 25 | r13 | Santos LagunaSantos Laguna | 2 - 3 | Atletico de San LuisAtletico de S |
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| 07 Apr 25 | r14 | TolucaToluca | 2 - 1 | Santos LagunaSantos Laguna |
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| 13 Apr 25 | r15 | Santos LagunaSantos Laguna | 1 - 2 | Queretaro FCQueretaro FC |
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| 17 Apr 25 | r16 | PumasPumas | 2 - 0 | Santos LagunaSantos Laguna |
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| 20 Apr 25 | r17 | Santos LagunaSantos Laguna | 0 - 4 | TijuanaTijuana |
Team 2024-2025 Schedules
América
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Atletico de San Luis
CD Guadalajara
Cruz Azul
Juárez
León
Mazatlán
Monterrey
Necaxa
Pachuca
Puebla
Pumas UNAM
Querétaro
Santos Laguna
Tigres UANL
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