| 25 Jul 21 | r01    | CD GuadalajaraCD Guadalajar | 1 - 2 | Atletico de San LuisAtletico de S |
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| 31 Jul 21 | r02 | PueblaPuebla | 0 - 2 | CD GuadalajaraCD Guadalajar |
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| 07 Aug 21 | r03  | CD GuadalajaraCD Guadalajar | 2 - 2 | FC JuarezFC Juarez |
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| 16 Aug 21 | r04 | SantosSantos | 0 - 0 | CD GuadalajaraCD Guadalajar |
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| 19 Aug 21 | r05 | CD GuadalajaraCD Guadalajar | 0 - 3 | LeonLeon |
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| 22 Aug 21 | r06 | MonterreyMonterrey | 0 - 0 | CD GuadalajaraCD Guadalajar |
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| 28 Aug 21 | r07 | CD GuadalajaraCD Guadalajar | 2 - 1 | NecaxaNecaxa |
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| 12 Sep 21 | r08 | PumasPumas | 0 - 0 | CD GuadalajaraCD Guadalajar |
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| 19 Sep 21 | r09 | CD GuadalajaraCD Guadalajar | 1 - 0 | PachucaPachuca |
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| 26 Sep 21 | r10 | CF AmericaCF America | 0 - 0 | CD GuadalajaraCD Guadalajar |
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| 30 Sep 21 | r11 | Queretaro FCQueretaro FC | 1 - 0 | CD GuadalajaraCD Guadalajar |
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| 03 Oct 21 | r12 | CD GuadalajaraCD Guadalajar | 0 - 1 | AtlasAtlas |
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| 17 Oct 21 | r13 | CD GuadalajaraCD Guadalajar | 2 - 0 | TolucaToluca |
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| 21 Oct 21 | r14 | TijuanaTijuana | 0 - 0 | CD GuadalajaraCD Guadalajar |
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| 24 Oct 21 | r15 | CD GuadalajaraCD Guadalajar | 1 - 1 | Cruz AzulCruz Azul |
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| 31 Oct 21 | r16 | TigresTigres | 2 - 1 | CD GuadalajaraCD Guadalajar |
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| 06 Nov 21 | r17 | MazatlánMazatlán | 0 - 1 | CD GuadalajaraCD Guadalajar |
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| 21 Nov 21 | r00  | PueblaPuebla | 2 - 2 | CD GuadalajaraCD Guadalajar |
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| 10 Jan 22 | r01 | CD GuadalajaraCD Guadalajar | 3 - 0 | MazatlánMazatlán |
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| 16 Jan 22 | r02 | PachucaPachuca | 2 - 1 | CD GuadalajaraCD Guadalajar |
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| 22 Jan 22 | r03 | CD GuadalajaraCD Guadalajar | 1 - 1 | Queretaro FCQueretaro FC |
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| 10 Feb 22 | r04 | FC JuarezFC Juarez | 1 - 3 | CD GuadalajaraCD Guadalajar |
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| 12 Feb 22 | r05 | CD GuadalajaraCD Guadalajar | 1 - 3 | TigresTigres |
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| 20 Feb 22 | r06 | LeonLeon | 2 - 1 | CD GuadalajaraCD Guadalajar |
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| 27 Feb 22 | r07 | CD GuadalajaraCD Guadalajar | 2 - 3 | PueblaPuebla |
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| 03 Mar 22 | r08 | Atletico de San LuisAtletico de S | 2 - 2 | CD GuadalajaraCD Guadalajar |
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| 06 Mar 22 | r09 | CD GuadalajaraCD Guadalajar | 1 - 0 | SantosSantos |
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| 13 Mar 22 | r10 | CD GuadalajaraCD Guadalajar | 0 - 0 | CF AmericaCF America |
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| 21 Mar 22 | r11 | AtlasAtlas | 1 - 1 | CD GuadalajaraCD Guadalajar |
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| 10 Apr 22 | r13 | TolucaToluca | 1 - 1 | CD GuadalajaraCD Guadalajar |
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| 14 Apr 22 | r12 | CD GuadalajaraCD Guadalajar | 1 - 3 | MonterreyMonterrey |
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| 17 Apr 22 | r14 | Cruz AzulCruz Azul | 0 - 1 | CD GuadalajaraCD Guadalajar |
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| 20 Apr 22 | r15 | CD GuadalajaraCD Guadalajar | 2 - 1 | TijuanaTijuana |
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| 24 Apr 22 | r16 | CD GuadalajaraCD Guadalajar | 3 - 1 | PumasPumas |
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| 30 Apr 22 | r17 | NecaxaNecaxa | 0 - 1 | CD GuadalajaraCD Guadalajar |
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| 09 May 22 | Qualifier | CD GuadalajaraCD Guadalajar | 4 - 1 | PumasPumas |
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| 13 May 22 | Playoff | CD GuadalajaraCD Guadalajar | 1 - 2 | AtlasAtlas |
| 15 May 22 | Playoff | AtlasAtlas | 1 - 1 | CD GuadalajaraCD Guadalajar |
Team 2021-2022 Schedules
América
Atlas
Atletico de San Luis
CD Guadalajara
Cruz Azul
Juárez
León
Mazatlán
Monterrey
Necaxa
Pachuca
Puebla
Pumas UNAM
Querétaro
Santos Laguna
Tigres UANL
Tijuana
Toluca
League Table
List
Poster
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