| 13 Aug 21 | r01     | Go Ahead EaglesGo Ahead Eagl | 0 - 1 | SC HeerenveenSC Heerenveen |
| 14 Aug 21 | r01 | RKC WaalwijkRKC Waalwijk | 1 - 0 | AZ AlkmaarAZ Alkmaar |
| 14 Aug 21 | r01 | SC Heracles AlmeloSC Heracles A | 0 - 2 | PSV EindhovenPSV Eindhoven |
| 14 Aug 21 | r01 | Fortuna SittardFortuna Sitta | 2 - 1 | FC TwenteFC Twente |
| 14 Aug 21 | r01 | AjaxAjax | 5 - 0 | NEC NijmegenNEC Nijmegen |
| 15 Aug 21 | r01 | SC CambuurSC Cambuur | 1 - 2 | FC GroningenFC Groningen |
| 15 Aug 21 | r01 | PEC ZwollePEC Zwolle | 0 - 1 | VitesseVitesse |
| 15 Aug 21 | r01 | FC UtrechtFC Utrecht | 4 - 0 | SpartaSparta |
| 15 Aug 21 | r01 | Willem IIWillem II | 0 - 4 | FeyenoordFeyenoord |
| |
| 20 Aug 21 | r02 | NEC NijmegenNEC Nijmegen | 2 - 0 | PEC ZwollePEC Zwolle |
| 21 Aug 21 | r02 | SC HeerenveenSC Heerenveen | 3 - 2 | RKC WaalwijkRKC Waalwijk |
| 21 Aug 21 | r02 | PSV EindhovenPSV Eindhoven | 4 - 1 | SC CambuurSC Cambuur |
| 21 Aug 21 | r02 | SpartaSparta | 1 - 1 | SC Heracles AlmeloSC Heracles A |
| 21 Aug 21 | r02 | FC GroningenFC Groningen | 0 - 0 | FC UtrechtFC Utrecht |
| 22 Aug 21 | r02 | FC TwenteFC Twente | 1 - 1 | AjaxAjax |
| 22 Aug 21 | r02 | FeyenoordFeyenoord | 2 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 22 Aug 21 | r02 | VitesseVitesse | 0 - 3 | Willem IIWillem II |
| |
| 27 Aug 21 | r03 | Fortuna SittardFortuna Sitta | 2 - 2 | RKC WaalwijkRKC Waalwijk |
| 28 Aug 21 | r03 | SC CambuurSC Cambuur | 2 - 0 | FC TwenteFC Twente |
| 28 Aug 21 | r03 | Go Ahead EaglesGo Ahead Eagl | 2 - 0 | SpartaSparta |
| 28 Aug 21 | r03 | PSV EindhovenPSV Eindhoven | 5 - 2 | FC GroningenFC Groningen |
| 28 Aug 21 | r03 | Willem IIWillem II | 1 - 0 | PEC ZwollePEC Zwolle |
| 29 Aug 21 | r03 | FC UtrechtFC Utrecht | 3 - 1 | FeyenoordFeyenoord |
| 29 Aug 21 | r03 | AjaxAjax | 5 - 0 | VitesseVitesse |
| 29 Aug 21 | r03 | SC Heracles AlmeloSC Heracles A | 0 - 1 | NEC NijmegenNEC Nijmegen |
| 29 Aug 21 | r03 | SC HeerenveenSC Heerenveen | 1 - 3 | AZ AlkmaarAZ Alkmaar |
| |
| 11 Sep 21 | r04 | FC TwenteFC Twente | 1 - 0 | FC UtrechtFC Utrecht |
| 11 Sep 21 | r04 | PEC ZwollePEC Zwolle | 0 - 2 | AjaxAjax |
| 11 Sep 21 | r04 | SC CambuurSC Cambuur | 5 - 2 | Go Ahead EaglesGo Ahead Eagl |
| 11 Sep 21 | r04 | AZ AlkmaarAZ Alkmaar | 0 - 3 | PSV EindhovenPSV Eindhoven |
| 12 Sep 21 | r04 | NEC NijmegenNEC Nijmegen | 0 - 0 | Willem IIWillem II |
| 12 Sep 21 | r04 | SpartaSparta | 3 - 1 | Fortuna SittardFortuna Sitta |
| 12 Sep 21 | r04 | FC GroningenFC Groningen | 1 - 1 | SC HeerenveenSC Heerenveen |
| 12 Sep 21 | r04 | RKC WaalwijkRKC Waalwijk | 1 - 2 | VitesseVitesse |
| |
| 17 Sep 21 | r05 | SpartaSparta | 1 - 1 | NEC NijmegenNEC Nijmegen |
| 18 Sep 21 | r05 | SC HeerenveenSC Heerenveen | 1 - 0 | Fortuna SittardFortuna Sitta |
| 18 Sep 21 | r05 | Willem IIWillem II | 2 - 1 | FC GroningenFC Groningen |
| 18 Sep 21 | r05 | AjaxAjax | 9 - 0 | SC CambuurSC Cambuur |
| 18 Sep 21 | r05 | FC UtrechtFC Utrecht | 2 - 2 | RKC WaalwijkRKC Waalwijk |
| 19 Sep 21 | r05 | Go Ahead EaglesGo Ahead Eagl | 1 - 0 | PEC ZwollePEC Zwolle |
| 19 Sep 21 | r05 | PSV EindhovenPSV Eindhoven | 0 - 4 | FeyenoordFeyenoord |
| 19 Sep 21 | r05 | VitesseVitesse | 1 - 4 | FC TwenteFC Twente |
| 19 Sep 21 | r05 | SC Heracles AlmeloSC Heracles A | 3 - 2 | AZ AlkmaarAZ Alkmaar |
| |
| 21 Sep 21 | r06 | Fortuna SittardFortuna Sitta | 0 - 5 | AjaxAjax |
| 21 Sep 21 | r06 | RKC WaalwijkRKC Waalwijk | 1 - 2 | Willem IIWillem II |
| 22 Sep 21 | r06 | Go Ahead EaglesGo Ahead Eagl | 1 - 2 | PSV EindhovenPSV Eindhoven |
| 22 Sep 21 | r06 | NEC NijmegenNEC Nijmegen | 0 - 3 | FC UtrechtFC Utrecht |
| 22 Sep 21 | r06 | FC GroningenFC Groningen | 0 - 1 | VitesseVitesse |
| 22 Sep 21 | r06 | PEC ZwollePEC Zwolle | 1 - 1 | SpartaSparta |
| 22 Sep 21 | r06 | FeyenoordFeyenoord | 3 - 1 | SC HeerenveenSC Heerenveen |
| 23 Sep 21 | r06 | SC CambuurSC Cambuur | 2 - 1 | SC Heracles AlmeloSC Heracles A |
| 23 Sep 21 | r06 | FC TwenteFC Twente | 3 - 1 | AZ AlkmaarAZ Alkmaar |
| |
| 25 Sep 21 | r07 | Willem IIWillem II | 2 - 1 | PSV EindhovenPSV Eindhoven |
| 25 Sep 21 | r07 | AjaxAjax | 3 - 0 | FC GroningenFC Groningen |
| 25 Sep 21 | r07 | VitesseVitesse | 1 - 1 | Fortuna SittardFortuna Sitta |
| 25 Sep 21 | r07 | FeyenoordFeyenoord | 5 - 3 | NEC NijmegenNEC Nijmegen |
| 25 Sep 21 | r07 | FC UtrechtFC Utrecht | 5 - 1 | PEC ZwollePEC Zwolle |
| 26 Sep 21 | r07 | SpartaSparta | 0 - 4 | SC CambuurSC Cambuur |
| 26 Sep 21 | r07 | AZ AlkmaarAZ Alkmaar | 5 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 26 Sep 21 | r07 | SC HeerenveenSC Heerenveen | 2 - 3 | FC TwenteFC Twente |
| 26 Sep 21 | r07 | SC Heracles AlmeloSC Heracles A | 1 - 0 | RKC WaalwijkRKC Waalwijk |
| |
| 01 Oct 21 | r08 | FC GroningenFC Groningen | 1 - 1 | FC TwenteFC Twente |
| 02 Oct 21 | r08 | RKC WaalwijkRKC Waalwijk | 1 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 02 Oct 21 | r08 | PEC ZwollePEC Zwolle | 0 - 1 | SC HeerenveenSC Heerenveen |
| 02 Oct 21 | r08 | SC Heracles AlmeloSC Heracles A | 3 - 2 | Willem IIWillem II |
| 02 Oct 21 | r08 | Fortuna SittardFortuna Sitta | 1 - 3 | NEC NijmegenNEC Nijmegen |
| 03 Oct 21 | r08 | AjaxAjax | 0 - 1 | FC UtrechtFC Utrecht |
| 03 Oct 21 | r08 | SC CambuurSC Cambuur | 1 - 3 | AZ AlkmaarAZ Alkmaar |
| 03 Oct 21 | r08 | VitesseVitesse | 2 - 1 | FeyenoordFeyenoord |
| 03 Oct 21 | r08 | PSV EindhovenPSV Eindhoven | 2 - 1 | SpartaSparta |
| |
| 16 Oct 21 | r09 | FeyenoordFeyenoord | 2 - 2 | RKC WaalwijkRKC Waalwijk |
| 16 Oct 21 | r09 | SC HeerenveenSC Heerenveen | 0 - 2 | AjaxAjax |
| 16 Oct 21 | r09 | Go Ahead EaglesGo Ahead Eagl | 4 - 2 | SC Heracles AlmeloSC Heracles A |
| 16 Oct 21 | r09 | Fortuna SittardFortuna Sitta | 1 - 0 | SC CambuurSC Cambuur |
| 16 Oct 21 | r09 | PSV EindhovenPSV Eindhoven | 3 - 1 | PEC ZwollePEC Zwolle |
| 17 Oct 21 | r09 | AZ AlkmaarAZ Alkmaar | 5 - 1 | FC UtrechtFC Utrecht |
| 17 Oct 21 | r09 | NEC NijmegenNEC Nijmegen | 0 - 1 | VitesseVitesse |
| 17 Oct 21 | r09 | SpartaSparta | 1 - 1 | FC GroningenFC Groningen |
| 17 Oct 21 | r09 | FC TwenteFC Twente | 1 - 1 | Willem IIWillem II |
| |
| 22 Oct 21 | r10 | Willem IIWillem II | 1 - 1 | Fortuna SittardFortuna Sitta |
| 23 Oct 21 | r10 | FC UtrechtFC Utrecht | 2 - 1 | SC HeerenveenSC Heerenveen |
| 23 Oct 21 | r10 | PEC ZwollePEC Zwolle | 1 - 0 | SC Heracles AlmeloSC Heracles A |
| 23 Oct 21 | r10 | RKC WaalwijkRKC Waalwijk | 1 - 0 | SpartaSparta |
| 24 Oct 21 | r10 | FC TwenteFC Twente | 1 - 2 | NEC NijmegenNEC Nijmegen |
| 24 Oct 21 | r10 | SC CambuurSC Cambuur | 2 - 3 | FeyenoordFeyenoord |
| 24 Oct 21 | r10 | VitesseVitesse | 1 - 2 | Go Ahead EaglesGo Ahead Eagl |
| 24 Oct 21 | r10 | AjaxAjax | 5 - 0 | PSV EindhovenPSV Eindhoven |
| 24 Oct 21 | r10 | FC GroningenFC Groningen | 2 - 0 | AZ AlkmaarAZ Alkmaar |
| |
| 30 Oct 21 | r11 | PSV EindhovenPSV Eindhoven | 5 - 2 | FC TwenteFC Twente |
| 30 Oct 21 | r11 | SC Heracles AlmeloSC Heracles A | 0 - 0 | AjaxAjax |
| 30 Oct 21 | r11 | SC HeerenveenSC Heerenveen | 1 - 2 | VitesseVitesse |
| 30 Oct 21 | r11 | AZ AlkmaarAZ Alkmaar | 3 - 2 | PEC ZwollePEC Zwolle |
| 31 Oct 21 | r11 | SpartaSparta | 0 - 1 | FeyenoordFeyenoord |
| 31 Oct 21 | r11 | NEC NijmegenNEC Nijmegen | 3 - 0 | FC GroningenFC Groningen |
| 31 Oct 21 | r11 | FC UtrechtFC Utrecht | 5 - 1 | Willem IIWillem II |
| 31 Oct 21 | r11 | RKC WaalwijkRKC Waalwijk | 0 - 1 | SC CambuurSC Cambuur |
| 31 Oct 21 | r11 | Go Ahead EaglesGo Ahead Eagl | 4 - 3 | Fortuna SittardFortuna Sitta |
| |
| 05 Nov 21 | r12 | FC TwenteFC Twente | 1 - 0 | SC Heracles AlmeloSC Heracles A |
| 06 Nov 21 | r12 | NEC NijmegenNEC Nijmegen | 1 - 1 | SC HeerenveenSC Heerenveen |
| 06 Nov 21 | r12 | Willem IIWillem II | 0 - 3 | SpartaSparta |
| 06 Nov 21 | r12 | PEC ZwollePEC Zwolle | 1 - 2 | SC CambuurSC Cambuur |
| 07 Nov 21 | r12 | FC GroningenFC Groningen | 1 - 1 | RKC WaalwijkRKC Waalwijk |
| 07 Nov 21 | r12 | Fortuna SittardFortuna Sitta | 1 - 4 | PSV EindhovenPSV Eindhoven |
| 07 Nov 21 | r12 | VitesseVitesse | 2 - 1 | FC UtrechtFC Utrecht |
| 07 Nov 21 | r12 | FeyenoordFeyenoord | 1 - 0 | AZ AlkmaarAZ Alkmaar |
| 07 Nov 21 | r12 | AjaxAjax | 0 - 0 | Go Ahead EaglesGo Ahead Eagl |
| |
| 20 Nov 21 | r13 | PSV EindhovenPSV Eindhoven | 2 - 0 | VitesseVitesse |
| 20 Nov 21 | r13 | SpartaSparta | 0 - 1 | FC TwenteFC Twente |
| 20 Nov 21 | r13 | AZ AlkmaarAZ Alkmaar | 1 - 1 | NEC NijmegenNEC Nijmegen |
| 20 Nov 21 | r13 | SC Heracles AlmeloSC Heracles A | 3 - 1 | Fortuna SittardFortuna Sitta |
| 21 Nov 21 | r13 | Go Ahead EaglesGo Ahead Eagl | 0 - 1 | FC GroningenFC Groningen |
| 21 Nov 21 | r13 | FeyenoordFeyenoord | 4 - 0 | PEC ZwollePEC Zwolle |
| 21 Nov 21 | r13 | SC HeerenveenSC Heerenveen | 2 - 1 | Willem IIWillem II |
| 21 Nov 21 | r13 | RKC WaalwijkRKC Waalwijk | 0 - 5 | AjaxAjax |
| 21 Nov 21 | r13 | SC CambuurSC Cambuur | 2 - 1 | FC UtrechtFC Utrecht |
| |
| 26 Nov 21 | r14 | NEC NijmegenNEC Nijmegen | 2 - 3 | SC CambuurSC Cambuur |
| 27 Nov 21 | r14 | Fortuna SittardFortuna Sitta | 1 - 4 | FC GroningenFC Groningen |
| 27 Nov 21 | r14 | PEC ZwollePEC Zwolle | 0 - 0 | RKC WaalwijkRKC Waalwijk |
| 27 Nov 21 | r14 | Willem IIWillem II | 0 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 28 Nov 21 | r14 | SpartaSparta | 0 - 1 | AjaxAjax |
| 28 Nov 21 | r14 | FC TwenteFC Twente | 0 - 0 | FeyenoordFeyenoord |
| 28 Nov 21 | r14 | FC UtrechtFC Utrecht | 1 - 0 | SC Heracles AlmeloSC Heracles A |
| 28 Nov 21 | r14 | SC HeerenveenSC Heerenveen | 1 - 1 | PSV EindhovenPSV Eindhoven |
| 28 Nov 21 | r14 | VitesseVitesse | 0 - 0 | AZ AlkmaarAZ Alkmaar |
| |
| 01 Dec 21 | r04 | FeyenoordFeyenoord | 2 - 1 | SC Heracles AlmeloSC Heracles A |
| |
| 02 Dec 21 | r02 | AZ AlkmaarAZ Alkmaar | 2 - 1 | Fortuna SittardFortuna Sitta |
| |
| 02 Dec 21 | r15 | AjaxAjax | 5 - 0 | Willem IIWillem II |
| 03 Dec 21 | r15 | FC GroningenFC Groningen | 1 - 1 | PEC ZwollePEC Zwolle |
| 04 Dec 21 | r15 | PSV EindhovenPSV Eindhoven | 4 - 1 | FC UtrechtFC Utrecht |
| 04 Dec 21 | r15 | SC CambuurSC Cambuur | 1 - 6 | VitesseVitesse |
| 04 Dec 21 | r15 | SC Heracles AlmeloSC Heracles A | 0 - 1 | SC HeerenveenSC Heerenveen |
| 05 Dec 21 | r15 | RKC WaalwijkRKC Waalwijk | 2 - 1 | NEC NijmegenNEC Nijmegen |
| 05 Dec 21 | r15 | AZ AlkmaarAZ Alkmaar | 3 - 1 | SpartaSparta |
| 05 Dec 21 | r15 | Go Ahead EaglesGo Ahead Eagl | 1 - 2 | FC TwenteFC Twente |
| 05 Dec 21 | r15 | FeyenoordFeyenoord | 5 - 0 | Fortuna SittardFortuna Sitta |
| |
| 10 Dec 21 | r16 | Willem IIWillem II | 1 - 3 | SC CambuurSC Cambuur |
| 11 Dec 21 | r16 | FC UtrechtFC Utrecht | 0 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 11 Dec 21 | r16 | SC HeerenveenSC Heerenveen | 0 - 0 | SpartaSparta |
| 11 Dec 21 | r16 | PEC ZwollePEC Zwolle | 0 - 1 | Fortuna SittardFortuna Sitta |
| 12 Dec 21 | r16 | FC TwenteFC Twente | 2 - 1 | RKC WaalwijkRKC Waalwijk |
| 12 Dec 21 | r16 | FC GroningenFC Groningen | 1 - 1 | FeyenoordFeyenoord |
| 12 Dec 21 | r16 | VitesseVitesse | 2 - 1 | SC Heracles AlmeloSC Heracles A |
| 12 Dec 21 | r16 | AjaxAjax | 1 - 2 | AZ AlkmaarAZ Alkmaar |
| 12 Dec 21 | r16 | NEC NijmegenNEC Nijmegen | 1 - 2 | PSV EindhovenPSV Eindhoven |
| |
| 18 Dec 21 | r17 | Fortuna SittardFortuna Sitta | 2 - 2 | FC UtrechtFC Utrecht |
| 18 Dec 21 | r17 | SpartaSparta | 2 - 2 | VitesseVitesse |
| 18 Dec 21 | r17 | AZ AlkmaarAZ Alkmaar | 4 - 1 | Willem IIWillem II |
| 18 Dec 21 | r17 | SC Heracles AlmeloSC Heracles A | 4 - 2 | FC GroningenFC Groningen |
| 18 Dec 21 | r17 | PEC ZwollePEC Zwolle | 1 - 3 | FC TwenteFC Twente |
| 19 Dec 21 | r17 | SC CambuurSC Cambuur | 1 - 2 | SC HeerenveenSC Heerenveen |
| 19 Dec 21 | r17 | FeyenoordFeyenoord | 0 - 2 | AjaxAjax |
| 19 Dec 21 | r17 | Go Ahead EaglesGo Ahead Eagl | 0 - 2 | NEC NijmegenNEC Nijmegen |
| 19 Dec 21 | r17 | RKC WaalwijkRKC Waalwijk | 1 - 4 | PSV EindhovenPSV Eindhoven |
| |
| 21 Dec 21 | r18 | VitesseVitesse | 1 - 0 | PEC ZwollePEC Zwolle |
| 21 Dec 21 | r18 | AZ AlkmaarAZ Alkmaar | 1 - 0 | FC GroningenFC Groningen |
| 22 Dec 21 | r18 | SC HeerenveenSC Heerenveen | 0 - 3 | FeyenoordFeyenoord |
| 22 Dec 21 | r18 | Willem IIWillem II | 0 - 1 | NEC NijmegenNEC Nijmegen |
| 22 Dec 21 | r18 | SC Heracles AlmeloSC Heracles A | 1 - 1 | SC CambuurSC Cambuur |
| 22 Dec 21 | r18 | FC UtrechtFC Utrecht | 1 - 1 | FC TwenteFC Twente |
| 22 Dec 21 | r18 | AjaxAjax | 5 - 0 | Fortuna SittardFortuna Sitta |
| 23 Dec 21 | r18 | PSV EindhovenPSV Eindhoven | 2 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 23 Dec 21 | r18 | SpartaSparta | 1 - 1 | RKC WaalwijkRKC Waalwijk |
| |
| 14 Jan 22 | r19 | PEC ZwollePEC Zwolle | 2 - 0 | Willem IIWillem II |
| 15 Jan 22 | r19 | NEC NijmegenNEC Nijmegen | 0 - 0 | SC Heracles AlmeloSC Heracles A |
| 15 Jan 22 | r19 | FeyenoordFeyenoord | 0 - 1 | VitesseVitesse |
| 15 Jan 22 | r19 | FC TwenteFC Twente | 2 - 0 | SC HeerenveenSC Heerenveen |
| 15 Jan 22 | r19 | Go Ahead EaglesGo Ahead Eagl | 0 - 2 | RKC WaalwijkRKC Waalwijk |
| 16 Jan 22 | r19  | FC UtrechtFC Utrecht | 0 - 3 | AjaxAjax |
| 16 Jan 22 | r19 | FC GroningenFC Groningen | 0 - 1 | PSV EindhovenPSV Eindhoven |
| 16 Jan 22 | r19 | SC CambuurSC Cambuur | 1 - 1 | SpartaSparta |
| 16 Jan 22 | r19 | Fortuna SittardFortuna Sitta | 1 - 2 | AZ AlkmaarAZ Alkmaar |
| |
| 22 Jan 22 | r20 | VitesseVitesse | 1 - 3 | FC GroningenFC Groningen |
| 22 Jan 22 | r20 | AZ AlkmaarAZ Alkmaar | 0 - 0 | SC CambuurSC Cambuur |
| 22 Jan 22 | r20 | SC HeerenveenSC Heerenveen | 0 - 1 | PEC ZwollePEC Zwolle |
| 22 Jan 22 | r20 | Willem IIWillem II | 0 - 1 | FC TwenteFC Twente |
| 23 Jan 22 | r20 | NEC NijmegenNEC Nijmegen | 1 - 4 | FeyenoordFeyenoord |
| 23 Jan 22 | r20 | SC Heracles AlmeloSC Heracles A | 1 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 23 Jan 22 | r20 | PSV EindhovenPSV Eindhoven | 1 - 2 | AjaxAjax |
| 23 Jan 22 | r20 | SpartaSparta | 0 - 3 | FC UtrechtFC Utrecht |
| 23 Jan 22 | r20 | RKC WaalwijkRKC Waalwijk | 2 - 1 | Fortuna SittardFortuna Sitta |
| |
| 05 Feb 22 | r21 | FC UtrechtFC Utrecht | 3 - 2 | SC CambuurSC Cambuur |
| 05 Feb 22 | r21 | Fortuna SittardFortuna Sitta | 2 - 0 | SC HeerenveenSC Heerenveen |
| 05 Feb 22 | r21 | PEC ZwollePEC Zwolle | 1 - 1 | NEC NijmegenNEC Nijmegen |
| 05 Feb 22 | r21 | PSV EindhovenPSV Eindhoven | 1 - 2 | AZ AlkmaarAZ Alkmaar |
| 05 Feb 22 | r21 | FC TwenteFC Twente | 3 - 0 | VitesseVitesse |
| 06 Feb 22 | r21 | FeyenoordFeyenoord | 4 - 0 | SpartaSparta |
| 06 Feb 22 | r21 | FC GroningenFC Groningen | 2 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 06 Feb 22 | r21 | Willem IIWillem II | 3 - 1 | RKC WaalwijkRKC Waalwijk |
| 06 Feb 22 | r21 | AjaxAjax | 3 - 0 | SC Heracles AlmeloSC Heracles A |
| |
| 11 Feb 22 | r22 | SC Heracles AlmeloSC Heracles A | 1 - 0 | FC UtrechtFC Utrecht |
| 12 Feb 22 | r22 | FC GroningenFC Groningen | 0 - 1 | Fortuna SittardFortuna Sitta |
| 12 Feb 22 | r22 | SC CambuurSC Cambuur | 3 - 4 | PEC ZwollePEC Zwolle |
| 12 Feb 22 | r22 | VitesseVitesse | 0 - 5 | PSV EindhovenPSV Eindhoven |
| 13 Feb 22 | r22 | Go Ahead EaglesGo Ahead Eagl | 1 - 4 | AZ AlkmaarAZ Alkmaar |
| 13 Feb 22 | r22 | SpartaSparta | 1 - 0 | Willem IIWillem II |
| 13 Feb 22 | r22 | RKC WaalwijkRKC Waalwijk | 0 - 2 | FeyenoordFeyenoord |
| 13 Feb 22 | r22 | SC HeerenveenSC Heerenveen | 0 - 1 | NEC NijmegenNEC Nijmegen |
| 13 Feb 22 | r22 | AjaxAjax | 5 - 0 | FC TwenteFC Twente |
| |
| 19 Feb 22 | r23 | NEC NijmegenNEC Nijmegen | 1 - 1 | RKC WaalwijkRKC Waalwijk |
| 19 Feb 22 | r23 | Willem IIWillem II | 0 - 1 | AjaxAjax |
| 19 Feb 22 | r23 | AZ AlkmaarAZ Alkmaar | 2 - 1 | SC Heracles AlmeloSC Heracles A |
| 20 Feb 22 | r23 | PEC ZwollePEC Zwolle | 1 - 1 | FC GroningenFC Groningen |
| 20 Feb 22 | r23 | FC TwenteFC Twente | 2 - 2 | Go Ahead EaglesGo Ahead Eagl |
| 20 Feb 22 | r23 | FeyenoordFeyenoord | 3 - 1 | SC CambuurSC Cambuur |
| 20 Feb 22 | r23 | FC UtrechtFC Utrecht | 1 - 1 | VitesseVitesse |
| 20 Feb 22 | r23 | PSV EindhovenPSV Eindhoven | 3 - 1 | SC HeerenveenSC Heerenveen |
| |
| 25 Feb 22 | r24 | RKC WaalwijkRKC Waalwijk | 1 - 2 | FC TwenteFC Twente |
| 26 Feb 22 | r24 | SC Heracles AlmeloSC Heracles A | 2 - 0 | PEC ZwollePEC Zwolle |
| 26 Feb 22 | r24 | FC GroningenFC Groningen | 1 - 0 | Willem IIWillem II |
| 26 Feb 22 | r24 | SC CambuurSC Cambuur | 2 - 1 | Fortuna SittardFortuna Sitta |
| 27 Feb 22 | r24 | AZ AlkmaarAZ Alkmaar | 2 - 1 | FeyenoordFeyenoord |
| 27 Feb 22 | r24 | VitesseVitesse | 4 - 1 | NEC NijmegenNEC Nijmegen |
| 27 Feb 22 | r24 | SpartaSparta | 1 - 2 | PSV EindhovenPSV Eindhoven |
| 27 Feb 22 | r24 | Go Ahead EaglesGo Ahead Eagl | 2 - 1 | AjaxAjax |
| 27 Feb 22 | r24 | SC HeerenveenSC Heerenveen | 1 - 2 | FC UtrechtFC Utrecht |
| |
| 05 Mar 22 | r25 | Willem IIWillem II | 0 - 0 | SC HeerenveenSC Heerenveen |
| 05 Mar 22 | r25 | Go Ahead EaglesGo Ahead Eagl | 1 - 1 | FC UtrechtFC Utrecht |
| 05 Mar 22 | r25 | FeyenoordFeyenoord | 1 - 1 | FC GroningenFC Groningen |
| 06 Mar 22 | r25 | PSV EindhovenPSV Eindhoven | 3 - 1 | SC Heracles AlmeloSC Heracles A |
| 06 Mar 22 | r25 | FC TwenteFC Twente | 1 - 0 | SC CambuurSC Cambuur |
| 06 Mar 22 | r25 | AjaxAjax | 3 - 2 | RKC WaalwijkRKC Waalwijk |
| 06 Mar 22 | r25 | NEC NijmegenNEC Nijmegen | 1 - 3 | AZ AlkmaarAZ Alkmaar |
| 06 Mar 22 | r25 | Fortuna SittardFortuna Sitta | 0 - 1 | PEC ZwollePEC Zwolle |
| |
| 11 Mar 22 | r26 | SC CambuurSC Cambuur | 2 - 3 | AjaxAjax |
| 12 Mar 22 | r26 | SpartaSparta | 1 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 12 Mar 22 | r26 | FC GroningenFC Groningen | 4 - 3 | NEC NijmegenNEC Nijmegen |
| 12 Mar 22 | r26 | RKC WaalwijkRKC Waalwijk | 0 - 0 | SC HeerenveenSC Heerenveen |
| 13 Mar 22 | r26 | Fortuna SittardFortuna Sitta | 1 - 0 | Willem IIWillem II |
| 13 Mar 22 | r26 | FC UtrechtFC Utrecht | 0 - 1 | PSV EindhovenPSV Eindhoven |
| 13 Mar 22 | r26 | SC Heracles AlmeloSC Heracles A | 0 - 0 | VitesseVitesse |
| 13 Mar 22 | r26 | PEC ZwollePEC Zwolle | 1 - 2 | FeyenoordFeyenoord |
| 13 Mar 22 | r26 | AZ AlkmaarAZ Alkmaar | 0 - 1 | FC TwenteFC Twente |
| |
| 18 Mar 22 | r27 | SC HeerenveenSC Heerenveen | 2 - 0 | SC Heracles AlmeloSC Heracles A |
| 19 Mar 22 | r27 | Go Ahead EaglesGo Ahead Eagl | 3 - 0 | SC CambuurSC Cambuur |
| 19 Mar 22 | r27 | FC TwenteFC Twente | 1 - 0 | PEC ZwollePEC Zwolle |
| 19 Mar 22 | r27 | NEC NijmegenNEC Nijmegen | 0 - 0 | SpartaSparta |
| 20 Mar 22 | r27 | FC UtrechtFC Utrecht | 1 - 3 | FC GroningenFC Groningen |
| 20 Mar 22 | r27 | AjaxAjax | 3 - 2 | FeyenoordFeyenoord |
| 20 Mar 22 | r27 | PSV EindhovenPSV Eindhoven | 5 - 0 | Fortuna SittardFortuna Sitta |
| 20 Mar 22 | r27 | VitesseVitesse | 1 - 2 | RKC WaalwijkRKC Waalwijk |
| 20 Mar 22 | r27 | Willem IIWillem II | 2 - 2 | AZ AlkmaarAZ Alkmaar |
| |
| 02 Apr 22 | r28 | FC GroningenFC Groningen | 1 - 3 | AjaxAjax |
| 02 Apr 22 | r28 | FC TwenteFC Twente | 3 - 3 | PSV EindhovenPSV Eindhoven |
| 02 Apr 22 | r28 | AZ AlkmaarAZ Alkmaar | 3 - 1 | VitesseVitesse |
| 02 Apr 22 | r28 | RKC WaalwijkRKC Waalwijk | 1 - 1 | FC UtrechtFC Utrecht |
| 02 Apr 22 | r28 | FeyenoordFeyenoord | 2 - 0 | Willem IIWillem II |
| 03 Apr 22 | r28 | PEC ZwollePEC Zwolle | 0 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 03 Apr 22 | r28 | Fortuna SittardFortuna Sitta | 0 - 2 | SC Heracles AlmeloSC Heracles A |
| 03 Apr 22 | r28 | SpartaSparta | 1 - 1 | SC HeerenveenSC Heerenveen |
| 03 Apr 22 | r28 | SC CambuurSC Cambuur | 1 - 2 | NEC NijmegenNEC Nijmegen |
| |
| 08 Apr 22 | r29 | Go Ahead EaglesGo Ahead Eagl | 4 - 0 | Willem IIWillem II |
| 09 Apr 22 | r29 | FC UtrechtFC Utrecht | 1 - 1 | Fortuna SittardFortuna Sitta |
| 09 Apr 22 | r29 | AjaxAjax | 2 - 1 | SpartaSparta |
| 09 Apr 22 | r29 | NEC NijmegenNEC Nijmegen | 0 - 2 | FC TwenteFC Twente |
| 10 Apr 22 | r29 | SC HeerenveenSC Heerenveen | 3 - 1 | FC GroningenFC Groningen |
| 10 Apr 22 | r29 | PSV EindhovenPSV Eindhoven | 2 - 0 | RKC WaalwijkRKC Waalwijk |
| 10 Apr 22 | r29 | VitesseVitesse | 1 - 0 | SC CambuurSC Cambuur |
| 10 Apr 22 | r29 | SC Heracles AlmeloSC Heracles A | 1 - 4 | FeyenoordFeyenoord |
| 10 Apr 22 | r29 | PEC ZwollePEC Zwolle | 2 - 1 | AZ AlkmaarAZ Alkmaar |
| |
| 16 Apr 22 | r23 | Fortuna SittardFortuna Sitta | 3 - 0 | SpartaSparta |
| |
| 19 Apr 22 | r25 | VitesseVitesse | 0 - 1 | SpartaSparta |
| |
| 22 Apr 22 | r30 | FC TwenteFC Twente | 2 - 0 | SpartaSparta |
| 23 Apr 22 | r30 | NEC NijmegenNEC Nijmegen | 0 - 1 | AjaxAjax |
| 23 Apr 22 | r30 | AZ AlkmaarAZ Alkmaar | 2 - 1 | SC HeerenveenSC Heerenveen |
| 23 Apr 22 | r30 | RKC WaalwijkRKC Waalwijk | 0 - 2 | PEC ZwollePEC Zwolle |
| 23 Apr 22 | r30 | SC CambuurSC Cambuur | 1 - 2 | PSV EindhovenPSV Eindhoven |
| 24 Apr 22 | r30 | Willem IIWillem II | 1 - 0 | VitesseVitesse |
| 24 Apr 22 | r30 | FC GroningenFC Groningen | 0 - 1 | SC Heracles AlmeloSC Heracles A |
| 24 Apr 22 | r30 | FeyenoordFeyenoord | 2 - 1 | FC UtrechtFC Utrecht |
| 24 Apr 22 | r30 | Fortuna SittardFortuna Sitta | 1 - 0 | Go Ahead EaglesGo Ahead Eagl |
| |
| 29 Apr 22 | r31 | FC UtrechtFC Utrecht | 1 - 0 | NEC NijmegenNEC Nijmegen |
| 30 Apr 22 | r31 | AjaxAjax | 3 - 0 | PEC ZwollePEC Zwolle |
| 30 Apr 22 | r31 | SC Heracles AlmeloSC Heracles A | 1 - 1 | FC TwenteFC Twente |
| 30 Apr 22 | r31 | SpartaSparta | 1 - 1 | AZ AlkmaarAZ Alkmaar |
| 01 May 22 | r31 | SC HeerenveenSC Heerenveen | 3 - 3 | SC CambuurSC Cambuur |
| 01 May 22 | r31 | Go Ahead EaglesGo Ahead Eagl | 1 - 2 | VitesseVitesse |
| 01 May 22 | r31 | PSV EindhovenPSV Eindhoven | 4 - 2 | Willem IIWillem II |
| 01 May 22 | r31 | Fortuna SittardFortuna Sitta | 1 - 3 | FeyenoordFeyenoord |
| 01 May 22 | r31 | RKC WaalwijkRKC Waalwijk | 3 - 1 | FC GroningenFC Groningen |
| |
| 06 May 22 | r32 | SC CambuurSC Cambuur | 1 - 1 | RKC WaalwijkRKC Waalwijk |
| 07 May 22 | r32 | FC TwenteFC Twente | 1 - 2 | Fortuna SittardFortuna Sitta |
| 07 May 22 | r32 | PEC ZwollePEC Zwolle | 1 - 1 | FC UtrechtFC Utrecht |
| 07 May 22 | r32 | Willem IIWillem II | 2 - 0 | SC Heracles AlmeloSC Heracles A |
| 07 May 22 | r32 | FC GroningenFC Groningen | 1 - 2 | SpartaSparta |
| 08 May 22 | r32 | NEC NijmegenNEC Nijmegen | 1 - 0 | Go Ahead EaglesGo Ahead Eagl |
| 08 May 22 | r32 | AZ AlkmaarAZ Alkmaar | 2 - 2 | AjaxAjax |
| 08 May 22 | r32 | VitesseVitesse | 1 - 2 | SC HeerenveenSC Heerenveen |
| 08 May 22 | r32 | FeyenoordFeyenoord | 2 - 2 | PSV EindhovenPSV Eindhoven |
| |
| 09 May 22 | Playoff | De GraafschapDe Graafschap | 1 - 1 | FC EindhovenFC Eindhoven |
| 10 May 22 | Playoff | NAC BredaNAC Breda | 1 - 2 | ADO Den HaagADO Den Haag |
| 10 May 22 | Playoff | ExcelsiorExcelsior | 2 - 2 | Roda JCRoda JC |
| |
| 11 May 22 | r33 | AjaxAjax | 5 - 0 | SC HeerenveenSC Heerenveen |
| 11 May 22 | r33 | SC CambuurSC Cambuur | 1 - 1 | Willem IIWillem II |
| 11 May 22 | r33 | Fortuna SittardFortuna Sitta | 1 - 2 | VitesseVitesse |
| 11 May 22 | r33 | Go Ahead EaglesGo Ahead Eagl | 0 - 1 | FeyenoordFeyenoord |
| 11 May 22 | r33 | PSV EindhovenPSV Eindhoven | 3 - 2 | NEC NijmegenNEC Nijmegen |
| 11 May 22 | r33 | RKC WaalwijkRKC Waalwijk | 2 - 0 | SC Heracles AlmeloSC Heracles A |
| 11 May 22 | r33 | SpartaSparta | 2 - 0 | PEC ZwollePEC Zwolle |
| 11 May 22 | r33 | FC TwenteFC Twente | 3 - 0 | FC GroningenFC Groningen |
| 11 May 22 | r33 | FC UtrechtFC Utrecht | 2 - 2 | AZ AlkmaarAZ Alkmaar |
| |
| 13 May 22 | Playoff | FC EindhovenFC Eindhoven | 3 - 1 | De GraafschapDe Graafschap |
| 14 May 22 | Playoff | ADO Den HaagADO Den Haag | 2 - 1 | NAC BredaNAC Breda |
| 14 May 22 | Playoff | Roda JCRoda JC | 0 - 2 | ExcelsiorExcelsior |
| |
| 15 May 22 | r34 | PEC ZwollePEC Zwolle | 1 - 2 | PSV EindhovenPSV Eindhoven |
| 15 May 22 | r34 | AZ AlkmaarAZ Alkmaar | 1 - 3 | RKC WaalwijkRKC Waalwijk |
| 15 May 22 | r34 | FeyenoordFeyenoord | 1 - 2 | FC TwenteFC Twente |
| 15 May 22 | r34 | FC GroningenFC Groningen | 2 - 3 | SC CambuurSC Cambuur |
| 15 May 22 | r34 | SC Heracles AlmeloSC Heracles A | 1 - 3 | SpartaSparta |
| 15 May 22 | r34 | SC HeerenveenSC Heerenveen | 3 - 1 | Go Ahead EaglesGo Ahead Eagl |
| 15 May 22 | r34 | NEC NijmegenNEC Nijmegen | 0 - 1 | Fortuna SittardFortuna Sitta |
| 15 May 22 | r34 | VitesseVitesse | 2 - 2 | AjaxAjax |
| 15 May 22 | r34 | Willem IIWillem II | 3 - 0 | FC UtrechtFC Utrecht |
| |
| 17 May 22 | Playoff | ADO Den HaagADO Den Haag | 2 - 1 | FC EindhovenFC Eindhoven |
| 18 May 22 | Playoff | ExcelsiorExcelsior | 3 - 0 | SC Heracles AlmeloSC Heracles A |
| 19 May 22 | Playoff | SC HeerenveenSC Heerenveen | 3 - 2 | AZ AlkmaarAZ Alkmaar |
| 19 May 22 | Playoff | FC UtrechtFC Utrecht | 3 - 1 | VitesseVitesse |
| 21 May 22 | Playoff | FC EindhovenFC Eindhoven | 1 - 2 | ADO Den HaagADO Den Haag |
| 21 May 22 | Playoff | SC Heracles AlmeloSC Heracles A | 1 - 3 | ExcelsiorExcelsior |
| 22 May 22 | Playoff | AZ AlkmaarAZ Alkmaar | 2 - 0 | SC HeerenveenSC Heerenveen |
| 22 May 22 | Playoff | VitesseVitesse | 3 - 0 | FC UtrechtFC Utrecht |
| 24 May 22 | Playoff | ExcelsiorExcelsior | 1 - 1 | ADO Den HaagADO Den Haag |
| 26 May 22 | Playoff | VitesseVitesse | 2 - 1 | AZ AlkmaarAZ Alkmaar |
| 29 May 22 | Playoff | AZ AlkmaarAZ Alkmaar | 6 - 1 | VitesseVitesse |
| 29 May 22 | Playoff | ADO Den HaagADO Den Haag | 4 - 4 | ExcelsiorExcelsior |
Team 2021-2022 Schedules
Ajax
AZ Alkmaar
Excelsior
FC Volendam
Feyenoord
Fortuna Sittard
Go Ahead Eagles
Groningen
Heerenveen
Heracles Almelo
NAC Breda
NEC Nijmegen
PEC Zwolle
PSV Eindhoven
SC Telstar
Sparta Rotterdam
Twente
Utrecht
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