| 17 Aug 25 | r01        | Nottingham ForestNottingham Fo | 3 - 1 | BrentfordBrentford |
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| 23 Aug 25 | r02        | BrentfordBrentford | 1 - 0 | Aston VillaAston Villa |
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| 30 Aug 25 | r03        | SunderlandSunderland | 2 - 1 | BrentfordBrentford |
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| 13 Sep 25 | r04        | BrentfordBrentford | 2 - 2 | ChelseaChelsea |
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| 20 Sep 25 | r05        | FulhamFulham | 3 - 1 | BrentfordBrentford |
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| 27 Sep 25 | r06        | BrentfordBrentford | 3 - 1 | Manchester UnitedManchester Un |
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| 05 Oct 25 | r07        | BrentfordBrentford | 0 - 1 | Manchester CityManchester Ci |
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| 20 Oct 25 | r08        | West Ham UnitedWest Ham Unit | 0 - 2 | BrentfordBrentford |
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| 25 Oct 25 | r09        | BrentfordBrentford | 3 - 2 | LiverpoolLiverpool |
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| 01 Nov 25 | r10        | Crystal PalaceCrystal Palac | 2 - 0 | BrentfordBrentford |
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| 09 Nov 25 | r11        | BrentfordBrentford | 3 - 1 | Newcastle UnitedNewcastle Uni |
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| 22 Nov 25 | r12        | Brighton and Hove AlbionBrighton and | 2 - 1 | BrentfordBrentford |
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| 29 Nov 25 | r13        | BrentfordBrentford | 3 - 1 | BurnleyBurnley |
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| 03 Dec 25 | r14        | ArsenalArsenal | 2 - 0 | BrentfordBrentford |
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| 06 Dec 25 | r15        | Tottenham HotspurTottenham Hot | 2 - 0 | BrentfordBrentford |
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| 14 Dec 25 | r16        | BrentfordBrentford | 1 - 1 | Leeds UnitedLeeds United |
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| 20 Dec 25 | r17        | Wolverhampton WanderersWolverhampton | 0 - 2 | BrentfordBrentford |
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| 27 Dec 25 | r18        | BrentfordBrentford | 4 - 1 | BournemouthBournemouth |
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| 01 Jan 26 | r19        | BrentfordBrentford | 0 - 0 | Tottenham HotspurTottenham Hot |
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| 04 Jan 26 | r20        | EvertonEverton | 2 - 4 | BrentfordBrentford |
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| 07 Jan 26 | r21        | BrentfordBrentford | 3 - 0 | SunderlandSunderland |
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| 17 Jan 26 | r22        | ChelseaChelsea | 2 - 0 | BrentfordBrentford |
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| 25 Jan 26 | r23        | BrentfordBrentford | 0 - 2 | Nottingham ForestNottingham Fo |
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| 01 Feb 26 | r24        | Aston VillaAston Villa | 0 - 1 | BrentfordBrentford |
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| 07 Feb 26 | r25        | Newcastle UnitedNewcastle Uni | 2 - 3 | BrentfordBrentford |
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| 12 Feb 26 | r26        | BrentfordBrentford | 1 - 1 | ArsenalArsenal |
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| 21 Feb 26 | r27        | BrentfordBrentford | 0 - 2 | Brighton and Hove AlbionBrighton and |
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| 28 Feb 26 | r28        | BurnleyBurnley | 3 - 4 | BrentfordBrentford |
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| 03 Mar 26 | r29        | BournemouthBournemouth | 0 - 0 | BrentfordBrentford |
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| 16 Mar 26 | r30        | BrentfordBrentford | 2 - 2 | Wolverhampton WanderersWolverhampton |
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| 21 Mar 26 | r31        | Leeds UnitedLeeds United | 0 - 0 | BrentfordBrentford |
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| 11 Apr 26 | r32        | BrentfordBrentford | 2 - 2 | EvertonEverton |
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| 18 Apr 26 | r33        | BrentfordBrentford | 0 - 0 | FulhamFulham |
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| 27 Apr 26 | r34        | Manchester UnitedManchester Un | 2 - 1 | BrentfordBrentford |
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| 02 May 26 | r35        | BrentfordBrentford | 3 - 0 | West Ham UnitedWest Ham Unit |
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| 09 May 26 | r36        | Manchester CityManchester Ci | 3 - 0 | BrentfordBrentford |
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| 17 May 26 | r37        | BrentfordBrentford | 2 - 2 | Crystal PalaceCrystal Palac |
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| 24 May 26 | r38        | LiverpoolLiverpool | 1 - 1 | BrentfordBrentford |