14 Dec 21 | r02 | PEC Zwolle | 4 - 0 | MVV Maastric |
14 Dec 21 | r02 | ADO Den Haag | 4 - 2 | VV Gemert |
14 Dec 21 | r02 | FC Emmen | 0 - 1 | Excelsior Ma |
14 Dec 21 | r02 | NAC Breda | 3 - 2 | FC Utrecht |
14 Dec 21 | r02 | SC Telstar | 5 - 3 | SV Spakenbur |
15 Dec 21 | r02 | Vitesse | 2 - 1 | Sparta |
15 Dec 21 | r02 | AZ Alkmaar | 4 - 1 | SC Heracles |
15 Dec 21 | r02 | FC Twente | 2 - 1 | Feyenoord |
15 Dec 21 | r02 | Harkemase Bo | 0 - 5 | RKC Waalwijk |
15 Dec 21 | r02 | Excelsior | 2 - 4 | FC Groningen |
15 Dec 21 | r02 | Ajax | 4 - 0 | BVV Barendre |
15 Dec 21 | r02 | PSV Eindhove | 2 - 0 | Fortuna Sitt |
15 Dec 21 | r02 | Go Ahead Eag | 2 - 0 | Roda JC |
16 Dec 21 | r02 | SC Cambuur | 1 - 2 | NEC Nijmegen |
16 Dec 21 | r02 | Achilles Vee | 0 - 2 | DVS 33 Ermel |
16 Dec 21 | r02 | SC Heerenvee | 2 - 0 | De Treffers |