NFL 2021 9 2021-11-07 2021-11-07 https://r2.thesportsdb.com/images/media/event/thumb/utj1bj1624804161.jpg Kliff Kingsburys Arizona Cardinals travel to Santa Clara to face Kyle Shanahans San Francisco 49ers at Levis Stadium. The 49ers have struggled against the Cardinals in recent years, winning just three of the last 13 games. 1134540